6-Methoxy-1,2-dihydropyridine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 6-Methoxy-1,2-dihydropyridine
• 化学式: C₆H₉NO
• 分子量: 111.14
• InChiKey: DGTLQLPXXAIBQB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  21.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• PYRAZOLO-PYRROLIDIN-4-ONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE
  申请人：Novartis AG

  公开号：EP3004112B1

  公开（公告）日：2017-08-30
• [EN] 1H-PIRIDO[3, 4-B]INDOL-1-ONE DERIVATIVES<br/>[FR] DERIVES DE 1H-PIRIDO[3, 4-B]INDOL-1-UN
  申请人：NOVUSPHARMA SPA

  公开号：WO2001009129A2

  公开（公告）日：2001-02-08

  Compounds of formula (I) wherein: R is hydrogen; C1-C6 alkyl optionally substituted with one or more primary, secondary or tertiary amino groups, hydroxy or carboxy groups; C5-C6 cycloalkyl; aralkyl; heteroalkyl; aryl; heteroaryl; R1 is hydrogen; C1-C6 alkyl optionally substituted with one or more primary, secondary or tertiary amino groups, hydroxy or carboxy groups; C5-C6 cycloalkyl; aralkyl; heteroalkyl; R2 is hydrogen; C1-C6 alkyl optionally substituted with one or more primary, secondary or tertiary amino groups, hydroxy or carboxy groups; C5-C6 cycloalkyl; aralkyl; aryl; heteroaryl; heteroarylalkyl; C1-C6 acyl; X is one or more groups independently selected from hydrogen, C1-C6 alkyl, hydroxy, C1-C4 alkoxy, C1-C3 haloalkoxy, amino, C1-C3 alkylamino, C1-C3- acylamino, C1-C3 alkylsulfonylamino, halogen, nitro, cyano, carboxy, C1-C3 alkoxycarbonyl, sulfonyl, C1-C3- alkylsulfonyl, aminosulfonyl, C1-C3-alkylaminosulfonyl, trifluoromethyl with antitumor activity.