2-(3'-nitrophenyl)-4-[4"-(N-methyl-N-allylaminomethyl)phenyl]thiazole | 311312-86-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(3'-nitrophenyl)-4-[4"-(N-methyl-N-allylaminomethyl)phenyl]thiazole
• 英文别名: Benzenemethanamine, N-methyl-4-[2-(3-nitrophenyl)-4-thiazolyl]-N-2-propenyl-；N-methyl-N-[[4-[2-(3-nitrophenyl)-1,3-thiazol-4-yl]phenyl]methyl]prop-2-en-1-amine
• CAS: 311312-86-4
• 化学式: C₂₀H₁₉N₃O₂S
• 分子量: 365.456
• InChiKey: QCTLYDUOQFWFND-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  90.2
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• PYRIDYL SUBSTITUTED THIAZOLES
  申请人：——

  公开号：US20010000178A1

  公开（公告）日：2001-04-05

  Disclosed is a novel class of thiazole, thiadiazole, and oxadiazole compounds which are substituted at their nuclear carbons by aromatic moieties. These compounds exhibit antifungal activity against a variety of fungi including strains which have proven to be resistant to treatment with known antifungal agents such as Fluconazole.

  本发明涉及一类新型的噻唑、噻二唑和噁二唑化合物，其核碳被芳香基取代。这些化合物对多种真菌具有抗真菌活性，包括那些已被证明对已知抗真菌药物如氟康唑治疗产生抗药性的菌株。
• Novel class of thiomorpholino substituted thiazoles
  申请人：——

  公开号：US20010000177A1

  公开（公告）日：2001-04-05

  Disclosed is a novel class of thiazole, thiadiazole, and oxadiazole compounds which are substituted at their nuclear carbons by aromatic moieties. These compounds exhibit antifungal activity against a variety of fungi including strains which have proven to be resistant to treatment with known antifungal agents such as Fluconazole.

  本发明涉及一类新型的噻唑、噻二唑和噁二唑化合物，其核碳原子被芳香族基团取代。这些化合物对多种真菌表现出抗真菌活性，包括那些已被已知抗真菌药物如氟康唑治疗后仍然耐药的菌株。
• Novel class of piperazino substituted thiazoles
  申请人：——

  公开号：US20010000512A1

  公开（公告）日：2001-04-26

  Disclosed is a novel class of thiazole, thiadiazole, and oxadiazole compounds which are substituted at their nuclear carbons by aromatic moieties. These compounds exhibit antifungal activity against a variety of fungi including strains which have proven to be resistant to treatment with known antifungal agents such as Fluconazole.

  本发明涉及一类新型的噻唑、噻二唑和噁二唑化合物，它们的核碳被芳香族基替代。这些化合物对多种真菌表现出抗真菌活性，包括那些已被证明对已知的抗真菌药物如氟康唑的治疗具有抗药性的菌株。
• Thiadiazole antifungal agents
  申请人：——

  公开号：US20020002193A1

  公开（公告）日：2002-01-03

  Disclosed is a novel class of thiazole, thiadiazole, and oxadiazole compounds which are substituted at their nuclear carbons by aromatic moieties. These compounds exhibit antifungal activity against a variety of fungi including strains which have proven to be resistant to treatment with known antifungal agents such as Fluconazole.

  本发明涉及一种新型的噻唑、噻二唑和噁二唑化合物类，其核碳被芳香基团取代。这些化合物对各种真菌表现出抗真菌活性，包括那些已被证明对已知抗真菌药物如氟康唑治疗产生抗药性的菌株。
• US6156776A
  申请人：——

  公开号：US6156776A

  公开（公告）日：2000-12-05