5-oxo-1-(4-sulfophenyl)-4-[(4-sulfophenyl)hydrazinylidene]pyrazole-3-carboxylic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 5-oxo-1-(4-sulfophenyl)-4-[(4-sulfophenyl)hydrazinylidene]pyrazole-3-carboxylic acid
• 化学式: C₁₆H₁₂N₄O₉S₂
• 分子量: 468.4
• InChiKey: HOSOJXUREVIOMO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  31
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  220
• 氢给体数：
  4
• 氢受体数：
  12

文献信息

• Antiseptic solutions comprising chlorhexidine or its salt and an anionic dye and their preparation
  申请人：Combino Pharm, S.L.

  公开号：EP2499913A1

  公开（公告）日：2012-09-19

  The present invention relates to a stable antiseptic solution comprising: at least one di(4-chloro-phenyldiguanido) derivative or a pharmaceutically acceptable salt thereof, wherein said di(4-chloro-phenyldiguanido) derivative or a pharmaceutically acceptable salt thereof is a compound of formula (I) or a pharmaceutically acceptable salt thereof; and an at least one anionic dye, wherein the anionic dye or the total amount of anionic dyes present in the antiseptic solution are in an amount sufficient to stain a patient's skin or surgical field before surgery, when applied; wherein the antiseptic solution is essentially free of any cationic excipient.

  本发明涉及一种稳定的防腐溶液，包括：至少一种二（4-氯-苯基二胍基）衍生物或其药学上可接受的盐，其中所述二（4-氯-苯基二胍基）衍生物或其药学上可接受的盐是式 (I) 的化合物或其药学上可接受的盐； 和至少一种阴离子染料，其中阴离子染料或防腐溶液中存在的阴离子染料的总量足以在施用时使病人的皮肤或手术野在手术前染色；其中防腐溶液基本上不含任何阳离子赋形剂。
• Sealing agents, methods of making and uses thereof
  申请人：JAMES HARDIE TECHNOLOGY LIMITED

  公开号：US10259946B1

  公开（公告）日：2019-04-16

  Embodiments of the present disclosure relate generally to coating compositions which are suitable for use as sealing agents, methods of making and uses thereof. The disclosed coating compositions may be particularly suitable for application as a sealing agent to a burnished surface of a cementitious substrate, such as the cut face of a fiber cement board.

  本公开的实施方案一般涉及适合用作密封剂的涂层组合物及其制造方法和用途。所公开的涂料组合物可能特别适合用作水泥基材（如纤维水泥板的切割面）烧制表面的密封剂。
• Apparatuses and methods for generating a high-concentration protein product from a blanched biomass
  申请人：PARABEL LTD.

  公开号：US10194684B2

  公开（公告）日：2019-02-05

  The present disclosure relates, according to some embodiments, to apparatuses and methods for blanching (e.g., continuously) a microcrop (e.g., aquatic species, Lemna) and a high-concentration protein product derived therefrom. The present disclosure relates, according to some embodiments, to an apparatus for blanching a microcrop (e.g., Lemna, Wolffia) where the apparatus may include: a conveyance mechanism operable to transport a biomass to a blanching tray; an applicator operable to dispense a blanching solution onto at least one surface of the biomass within the blanching tray; the blanching tray oriented to receive a volume of the blanching solution from the applicator; and a vibratory mechanism capable of vibrating the blanching tray to generate a net motion of the received volume of the blanching solution within blanching tray such that a wave of blanching solution is formed. In some embodiments, a vibratory mechanism may be operable to generate a motive force capable of directing a biomass from a first side of a blanching tray to a second side of the blanching tray. In some embodiments, an apparatus may be capable of processing a biomass at a product flow rate ratio of about 7:1.

  根据一些实施例，本公开涉及用于焯水（例如连续焯水）微型作物（例如水生物种Lemna）和由此衍生的高浓度蛋白质产品的装置和方法。根据某些实施例，本公开涉及一种用于焯烫微型作物（例如、Lemna, Wolffia），该装置可包括：输送机构，可将生物质输送到焯水盘中；涂抹器，可将焯水溶液涂抹到焯水盘中生物质的至少一个表面上；焯水盘，可从涂抹器接收一定量的焯水溶液；以及振动机构，可振动焯水盘，使焯水盘中接收的焯水溶液产生净运动，从而形成焯水溶液波。在一些实施例中，振动机构可产生动力，将生物质从焯烫盘的第一侧导向焯烫盘的第二侧。在某些实施例中，设备可按约 7:1 的产品流速比处理生物质。
• Antimicrobial skin cream
  申请人：Ganga, Sr. Yvon Samba

  公开号：US10603337B1

  公开（公告）日：2020-03-31

  A cream for treating the skin may include gray clay kaolin; sodium lauryl ether sulfate; blue tartrazine; sodium chloride; menthol; metabisulfite sodium; gelatin; mineral oil; olive oil; oil of cloves; water; green tea; honey; talc; and aloe vera. The cream may also include apple perfume, vitamin E, vitamin D, vitamin C, vitamin B2, vitamin B5, vitamin H, vitamin B6, and vitamin D. The cream may also include fatty acids.

  用于治疗皮肤的面霜可包括灰色粘土高岭土、月桂醇醚硫酸钠、蓝色酒石酸、氯化钠、薄荷醇、焦亚硫酸钠、明胶、矿物油、橄榄油、丁香油、水、绿茶、蜂蜜、滑石粉和芦荟。膏霜还可包括苹果香水、维生素 E、维生素 D、维生素 C、维生素 B2、维生素 B5、维生素 H、维生素 B6 和维生素 D。
• Methods and systems for extracting reduced oxalic acid protein from aquatic species and compositions thereof
  申请人：Parabel Nutrition, Inc.

  公开号：US11325941B2

  公开（公告）日：2022-05-10

  The present disclosure relates, according to some embodiments, to methods and systems for purifying proteins having a reduced oxalic acid content from aquatic species and compositions thereof.

  根据一些实施例，本公开涉及从水生物种中纯化草酸含量降低的蛋白质及其组合物的方法和系统。