benzyl 2-methylimidazo[1,2-a]pyridine-3-carboxylate | 1304065-70-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: benzyl 2-methylimidazo[1,2-a]pyridine-3-carboxylate
• 英文别名: Benzyl 2-methylimidazo[1,2-a]pyridine-3-carboxylate
• CAS: 1304065-70-0
• 化学式: C₁₆H₁₄N₂O₂
• 分子量: 266.299
• InChiKey: VGPSLNFSAFJGPP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  43.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  吡啶 、 benzyl 3-[(2-methylpropan-2-yl)oxycarbonyldiazenyl]but-2-enoate 以 neat (no solvent) 为溶剂， 反应 4.0h， 以82%的产率得到benzyl 2-methylimidazo[1,2-a]pyridine-3-carboxylate
  参考文献：
  名称：

  A Novel Solvent-Free Approach to Imidazole Containing Nitrogen-Bridgehead Heterocycles

  摘要：

  A very simple domino reaction under solvent-free conditions of various pyridine-like heterocycles with 1,2-diaza-1,3-dienes produces in good yields imidazo[1,2-a]pyridines, imidazo[1,2-a]quinolines, and imidazo[2,1-a]isoquinolines. The advantage of this one-pot transformation lies in the use of simple pyridine-like compounds without prefunctionalization of the starting heterocycles.

  DOI：

  10.1021/ol4015267

文献信息

• Thermal and Microwave-Assisted Rapid Syntheses of Substituted Imidazo[1,2-a]pyridines Under Solvent- and Catalyst-Free Conditions
  作者：Subbarayappa Adimurthy、Kaushik Chunavala、Girdhar Joshi、Eringathodi Suresh

  DOI：10.1055/s-0030-1258405

  日期：2011.2

  microwave-assisted rapid syntheses of highly substituted imidazo[1,2-a]pyridine derivatives by reaction of aminopyridines and α-bromo-β-keto esters under solvent-free conditions are described. Reactions carried out under microwave irradiation give the highest yields of products in reaction times of less than two minutes. aminopyridines - α-bromo-β-keto esters - imidazo[1,2-a]pyridines - microwave irradiation

  描述了在无溶剂条件下通过氨基吡啶与α-溴-β-酮酯的反应进行热取代和微波辅助快速合成高度取代的咪唑并[1,2- a ]吡啶衍生物。在少于两分钟的反应时间内，在微波辐射下进行的反应可获得最高的产物收率。 氨基吡啶-α-溴-β-酮酸酯-咪唑并[1,2- a ]吡啶-微波辐射-无溶剂-热
• Polycyclic compound and organic light-emitting device including the same
  申请人：SAMSUNG DISPLAY CO., LTD.

  公开号：US10205104B2

  公开（公告）日：2019-02-12

  A polycyclic compound and an organic light-emitting device, the compound being represented by Formula 1:

  一种多环化合物和一种有机发光器件，该化合物由式 1 表示：
• Condensed-cyclic compound and organic light emitting device including the same
  申请人：SAMSUNG DISPLAY CO., LTD.

  公开号：US10186666B2

  公开（公告）日：2019-01-22

  A condensed-cyclic compound and an organic light-emitting device, the compound being represented by Formula 1:

  一种缩合环状化合物和一种有机发光器件，该化合物由式 1 表示：
• Organic light-emitting device
  申请人：SAMSUNG DISPLAY CO., LTD.

  公开号：US10361372B2

  公开（公告）日：2019-07-23

  An organic light-emitting device includes a first electrode; a second electrode facing the first electrode; and an organic layer between the first electrode and the second electrode, the organic layer including an emission layer and a first compound and a second compound, where the first compound includes at least one selected from compounds represented by Formula 1, and the second compound includes at least one selected from compounds represented by Formula 2:

  一种有机发光器件包括一个第一电极；一个面向第一电极的第二电极；以及一个位于第一电极和第二电极之间的有机层，该有机层包括一个发射层以及一个第一化合物和一个第二化合物，其中第一化合物包括从式 1 所代表的化合物中选出的至少一种，而第二化合物包括从式 2 所代表的化合物中选出的至少一种：
• Condensed cyclic compound and an organic light-emitting device including the same
  申请人：SAMSUNG DISPLAY CO., LTD.

  公开号：US10461262B2

  公开（公告）日：2019-10-29

  A condensed cyclic compound represented by Formula 1 and an organic light-emitting device including the same.

  一种由式 1 表示的缩合环状化合物和一种包括该化合物的有机发光器件。