cis-2,4-bisbenzoyloxytetraline | 72582-15-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: cis-2,4-bisbenzoyloxytetraline
• 英文别名: cis-2,3-bis-benzoyloxy-1,2,3,4-tetrahydro-naphthalene；cis-2,3-Bis-benzoyloxy-1,2,3,4-tetrahydro-naphthalin；2,3-Bis-benzoyloxy-1,2,3,4-tetrahydro-naphthalin；[(2R,3S)-3-benzoyloxy-1,2,3,4-tetrahydronaphthalen-2-yl] benzoate
• CAS: 72582-15-1
• 化学式: C₂₄H₂₀O₄
• 分子量: 372.42
• InChiKey: SXGDTDUFKVGOHA-SZPZYZBQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  cis-1,2,3,4-tetrahydro-naphthalene-2,3-diol 、 苯甲酰氯 生成 cis-2,4-bisbenzoyloxytetraline
  参考文献：
  名称：

  Bamberger; Lodter, Justus Liebigs Annalen der Chemie, 1895, vol. 288, p. 114

  摘要：

  DOI：

文献信息

• [EN] SYNTHETIC EPIGALLOCATECHIN GALLATE (EGCG) ANALOGS<br/>[FR] ANALOGUES SYNTHÉTIQUES DE GALLATE D'ÉPIGALLOCATÉCHINE (EGCG)
  申请人：UNIV MCGILL

  公开号：WO2012171114A1

  公开（公告）日：2012-12-20

  Synthetic polyphenolic compounds of formula (I), their modes of synthesis, and pharmaceutical compositions thereof are provided herein. Use of the compounds and compositions described herein for treating cancer and for treating metabolic disorders is also provided.

  本文提供了式（I）的合成多酚化合物，它们的合成方式以及药物组合物。本文还提供了利用所述化合物和组合物治疗癌症和治疗代谢紊乱的方法。
• Truncated Cinchona alkaloids as catalysts in enantioselective monobenzoylation of meso-1,2-diols
  作者：E. Peter Kündig、Alvaro Enriquez Garcia、Thierry Lomberget、Pablo Perez Garcia、Patrick Romanens

  DOI：10.1039/b808268e

  日期：——

  Readily synthesised quincorine and quincoridine derived chiral diamines efficiently catalyse the asymmetric monobenzoylation of cyclic and acyclic meso-1,2-diols.

  容易合成的喹啉和喹吖啶衍生手性二胺可高效催化环状和非环状介-1,2-二醇的不对称单苯甲酰化反应。
• Highly efficient catalytic asymmetric acylation of meso-1,2-diols with benzoyl chloride in the presence of a chirai diamine combined with Et3N
  作者：Takeshi Oriyama、Keisuke Imai、Tomohumi Sano、Takeshi Hosoya

  DOI：10.1016/s0040-4039(98)00523-1

  日期：1998.5

  Catalytic asymmetric acylation of meso-1,2-diols has been successfully performed by the reaction with benzoyl chloride in the presence of 0.5 mol% of chiral diamine derived from (S)-proline combined with a stoichiometric amount of triethylamine to give the corresponding monobenzoate with good to excellent enantioselectivities.

  在0.5摩尔％衍生自（S）-脯氨酸的手性二胺与化学计算量的三乙胺混合存在下，通过与苯甲酰氯反应成功地完成了内消旋-1,2-二醇的催化不对称酰化反应，得到了相应的单苯甲酸酯具有良好至优异的对映选择性。
• Asymmetric acylation of meso-diols with benzoyl halide in the presence of a chiral diamine
  作者：Takeshi Oriyama、Keisuke Imai、Takeshi Hosoya、Tomohumi Sano

  DOI：10.1016/s0040-4039(97)10558-5

  日期：1998.1

  Nonenzymatic desymmetrization of cis-1,2-cyclohexanediol by the asymmetric acylation with achiral benzoyl chloride in the presence of a chiral diamine derived from (S)-proline took place to give monobenzoate in high optical yield. (C) 1997 Elsevier Science Ltd. All rights reserved.
• Bamberger; Lodter, Justus Liebigs Annalen der Chemie, 1895, vol. 288, p. 114
  作者：Bamberger、Lodter

  DOI：——

  日期：——