8-hydroxy-14-[2-(2-hydroxyethylamino)ethyl]-10-[2-(methylamino)ethylamino]-14,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1,4,7,9,11,13(16)-hexaene-3,6-dione

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 8-hydroxy-14-[2-(2-hydroxyethylamino)ethyl]-10-[2-(methylamino)ethylamino]-14,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1,4,7,9,11,13(16)-hexaene-3,6-dione
• 化学式: C₂₁H₂₅N₅O₄
• 分子量: 411.5
• InChiKey: QDZIHWBJFUNKOF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  30
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  126
• 氢给体数：
  6
• 氢受体数：
  9

文献信息

• [EN] COMBINATION OF CIMETIDINE AND CYSTEINE DERIVATIVES FOR TREATING CANCER<br/>[FR] COMBINAISON DE DERIVES DE CIMETIDINE ET DE CYSTEINE POUR TRAITER LE CANCER
  申请人：ASTION ONCOLOGY APS

  公开号：WO2003045359A2

  公开（公告）日：2003-06-05

  The present invention relates to new substances in the form of chemical complexes comprising cimetidine or a derivative thereof and a cysteine derivative and to compositions comprising said complexes or combination. The invention further relates to the therapeutic effect of such combinations in relation to treating cancer, cancer chemoprevention or the suppression of hypersensitivity and/or inflammatory reactions of a mammal.