5,10,15,20-Tetrakis(4-chlorophenyl)porphyrin

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• 英文名称: 5,10,15,20-Tetrakis(4-chlorophenyl)porphyrin
• 化学式: C₄₄H₂₄Cl₄N₄
• 分子量: 750.5
• InChiKey: QWHDKEJNDCLNAD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.1
• 重原子数：
  52
• 可旋转键数：
  4
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  49.4
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] PLATINUM(II) RING-FUSED CHLORINS, METHODS AND USES THEREOF<br/>[FR] CHLORINES FUSIONNÉES À UN CYCLE PLATINE (II), PROCÉDÉS ET LEURS UTILISATIONS
  申请人：UNIV DE COIMBRA

  公开号：WO2017145092A1

  公开（公告）日：2017-08-31

  The present disclosure relates derivatives of platinum (II) ring-fused chlorins with a general formula I or II, more particularly derivatives, which are novel and stable near infrared luminescent compounds for imaging, sensing, optoelectronics applications and use in medicine or as a medicament. (Formula I and Formula II) (I) (II) This disclosure describes a series of novel, stable near infrared luminescent compounds based on platinum (II) ring-fused chlorins with the general formula I or II. This, coupled with excellent thermal and photochemical stability, makes them excellent materials for use in biological imaging, oxygen sensing and as emitting materials in optoelectronic applications, such as organic light emitting diodes (OLEDs) or bulk heterojunction photovoltaic cells. In addition, their chemical properties allow them to be chemically attached to specific biologically relevant molecules for targeted applications in imaging and theranostics.

  本公开涉及一种铂（II）环融合氯菊酯衍生物，其具有一般式I或II的衍生物，更具体地说，是一种新颖且稳定的近红外发光化合物，可用于成像、传感、光电子应用以及医学或作为药物。 (公式I和公式II) (I) (II) 本公开描述了一系列基于铂（II）环融合氯菊酯的新颖、稳定的近红外发光化合物，其具有优异的热稳定性和光化学稳定性，使它们成为生物成像、氧气传感和作为有机发光二极管（OLEDs）或体异质结光伏电池中的发射材料的优秀材料。此外，它们的化学性质使它们可以化学地连接到特定的生物相关分子上，用于成像和治疗学中的定向应用。
• Confined porphyrin Co(II) and preparation method and application thereof
  申请人：Zhejiang University of Technology

  公开号：US11420991B2

  公开（公告）日：2022-08-23

  A confined porphyrin Co(II), which is prepared by the following method: Equimolar amounts of aromatic aldehyde and pyrrole are condensed under acidic conditions to synthesize phenyl porphyrin compounds; the phenyl porphyrin compounds are metallized in a chloroform-methanol solution to obtain porphyrin Cu(II), which is brominated and demetallized to obtain confined porphyrin; the confined porphyrin is stirred and refluxed in a methanol solution for 12.0-24.0 h to obtain confined porphyrin Co(II). Its application is as follows: The confined porphyrin Co(II) is dissolved in cycloalkanes; the reaction system is sealed, and heated to 100 to 130° C. with stirring, to which oxygen is introduced to 0.2 to 3.0 MPa; the reaction is carried out for 3.0 to 24.0 h with stirring with the set temperature and oxygen pressure being maintained; and then the reaction solution is subjected to post-treatment to obtain the products.

  一种封闭的卟啉 Co(II)，其制备方法如下：等摩尔量的芳香醛和吡咯在酸性条件下缩合，合成苯基卟啉化合物；苯基卟啉化合物在氯仿-甲醇溶液中金属化，得到卟啉 Cu(II)，Cu(II)溴化后脱金属，得到封闭卟啉；封闭卟啉在甲醇溶液中搅拌回流 12.0-24.0 小时，得到封闭卟啉 Co(II)。其应用如下：将封闭卟啉 Co(II) 溶于环烷中；密封反应体系，在搅拌下加热至 100 至 130 摄氏度，通入 0.2 至 3.0 兆帕的氧气；在保持设定温度和氧气压力的情况下，在搅拌下反应 3.0 至 24.0 小时；然后对反应溶液进行后处理，得到产物。
• PLATINUM(II) RING-FUSED CHLORINS, METHODS AND USES THEREOF
  申请人：Universidade de Coimbra

  公开号：EP3419977A1

  公开（公告）日：2019-01-02
• CONFINED PORPHYRIN CO(II) AND PREPARATION METHOD AND APPLICATION THEREOF
  申请人：Zhejiang University of Technology

  公开号：US20210155650A1

  公开（公告）日：2021-05-27

  A confined porphyrin Co(II), which is prepared by the following method: Equimolar amounts of aromatic aldehyde and pyrrole are condensed under acidic conditions to synthesize phenyl porphyrin compounds; the phenyl porphyrin compounds are metallized in a chloroform-methanol solution to obtain porphyrin Cu(II), which is brominated and demetallized to obtain confined porphyrin; the confined porphyrin is stirred and refluxed in a methanol solution for 12.0-24.0 h to obtain confined porphyrin Co(II). Its application is as follows: The confined porphyrin Co(II) is dissolved in cycloalkanes; the reaction system is sealed, and heated to 100 to 130° C. with stirring, to which oxygen is introduced to 0.2 to 3.0 MPa; the reaction is carried out for 3.0 to 24.0 h with stirring with the set temperature and oxygen pressure being maintained; and then the reaction solution is subjected to post-treatment to obtain the products.
• US5103027A
  申请人：——

  公开号：US5103027A

  公开（公告）日：1992-04-07