toluenesulfonyl iodide | 42880-77-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: toluenesulfonyl iodide
• 英文别名: Phenylmethanesulfonyl iodide
• CAS: 42880-77-3
• 化学式: C₇H₇IO₂S
• 分子量: 282.102
• InChiKey: VZHBVOBRFKMADH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  42.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  硝基甲苯 、 toluenesulfonyl iodide 生成 Nitrodibenzyl sulfone
  参考文献：
  名称：

  Zeilstra,J.J.; Engberts,J.B.F.N., Recueil des Travaux Chimiques des Pays-Bas, 1974, vol. 93, p. 11 - 14

  摘要：

  DOI：

文献信息

• [EN] PYRROLO[2,3-D] PYRIMIDINE COMPOUNDS<br/>[FR] COMPOSÉS PYRROLO[2,3-D]PYRIMIDINE
  申请人：PFIZER

  公开号：WO2011045702A1

  公开（公告）日：2011-04-21

  Described herein are pyrrolo[2,3-d]pyrimidine compounds, their use as Janus Kinase (JAK) inhibitors, pharmaceutical compositions containing these compounds, and methods for their preparation.

  本文描述了吡咯并[2,3-d]嘧啶化合物，它们作为Janus激酶（JAK）抑制剂的用途，含有这些化合物的药物组合物，以及它们的制备方法。
• Polyethylene glycol derivative and preparation method thereof
  申请人：Hanmi Fine Chemical Co., Ltd.

  公开号：US11168180B2

  公开（公告）日：2021-11-09

  The present invention relates to a polyethylene glycol derivative and a preparation method thereof. A preparation process of a polyethylene glycol derivative, according to the present invention, may provide a novel polyethylene glycol derivative which can be utilized in various ways as a drug linker, and is appropriate and effective for mass production and is advantageous in reproducible mass production of high-quality products.

  本发明涉及聚乙二醇衍生物及其制备方法。根据本发明的聚乙二醇衍生物的制备过程，可以提供一种新型聚乙二醇衍生物，可以作为药物连接剂在各种方面得到利用，适用于大规模生产，有利于高质量产品的可重复生产。
• POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREOF
  申请人：Hanmi Fine Chemical Co., Ltd.

  公开号：EP3708561A2

  公开（公告）日：2020-09-16

  The present invention relates to a polyethylene glycol derivative and a preparation method thereof. A preparation process of a polyethylene glycol derivative, according to the present invention, may provide a novel polyethylene glycol derivative which can be utilized in various ways as a drug linker, and is appropriate and effective for mass production and is advantageous in reproducible mass production of high-quality products.

  本发明涉及一种聚乙二醇衍生物及其制备方法。根据本发明的聚乙二醇衍生物的制备方法，可以提供一种新型的聚乙二醇衍生物，该衍生物可以以各种方式用作药物连接剂，并且适合于大规模生产，效果显著，有利于高质量产品的可重复性大规模生产。
• REVERSE IODINE TRANSFER POLYMERIZATION METHOD AND COMPOSITIONS THEREFROM
  申请人：Dow Global Technologies LLC

  公开号：EP3924396A1

  公开（公告）日：2021-12-22
• Polyethylene Glycol Derivative And Preparation Method Thereof
  申请人：Hanmi Fine Chemical Co., Ltd.

  公开号：US20200231749A1

  公开（公告）日：2020-07-23

  The present invention relates to a polyethylene glycol derivative and a preparation method thereof. A preparation process of a polyethylene glycol derivative, according to the present invention, may provide a novel polyethylene glycol derivative which can be utilized in various ways as a drug linker, and is appropriate and effective for mass production and is advantageous in reproducible mass production of high-quality products.