acetophenone 4-aminobenzoylhydrazone

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: acetophenone 4-aminobenzoylhydrazone
• 英文别名: 4-amino-N-[(Z)-1-phenylethylideneamino]benzamide
• 化学式: C₁₅H₁₅N₃O
• 分子量: 253.304
• InChiKey: BZZLCHCWTXIPCQ-BOPFTXTBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  67.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  aqueous cadmium chloride 、 acetophenone 4-aminobenzoylhydrazone 以 乙醇 、 水 为溶剂， 以68%的产率得到poly[dichloroaqua(acetophenone 4-aminobenzoylhydrazone-κ2N(2),O,:μN(4'))cadmium(II)]
  参考文献：
  名称：

  Studies on Complexes of Co(II), Ni(II), Cu(II), and Cd(II) with Acetophenone and 4-Hydroxyacetophenone 4-Aminobenzoylhydrazones

  摘要：

  Metal(II) complexes of the types [M(L)Cl-2(H2O)] and [M(L')(2)Cl-2] [M = Co(II), Ni(II), Cu(II) and Cd(II), L = acetophenone- 4-aminobenzoylhydrazone (APABH), NH2C6H4CONHN=C(CH3)C6H5 and L'=4-hydroxyacetophenone 4-aminobenzoylhydrazone (HAPABH), NH2C6H4CONHN=C(CH3)C6H4OH were prepared and characterized by elemental and thermal analyses, molar conductance, magnetic susceptibility, infrared, NMR and electronic spectral studies. Some of the complexes were screened against E. coli, and Aspergillus niger for biological activity. The antibacterial activity of hydrazones and their complexes increases with increase of the concentration of solutions. At each concentration copper(II) complexes are more active than the Zinc(II) complexes with both hydrazones. The antifungal activity of the complexes is less than their parent ligands.

  DOI：

  10.1081/sim-120021935

文献信息

• Studies on Complexes of Co(II), Ni(II), Cu(II), and Cd(II) with Acetophenone and 4-Hydroxyacetophenone 4-Aminobenzoylhydrazones
  作者：B. Singh、K. K. Narang、Rachana Srivastava

  DOI：10.1081/sim-120021935

  日期：2003.1.7

  Metal(II) complexes of the types [M(L)Cl-2(H2O)] and [M(L')(2)Cl-2] [M = Co(II), Ni(II), Cu(II) and Cd(II), L = acetophenone- 4-aminobenzoylhydrazone (APABH), NH2C6H4CONHN=C(CH3)C6H5 and L'=4-hydroxyacetophenone 4-aminobenzoylhydrazone (HAPABH), NH2C6H4CONHN=C(CH3)C6H4OH were prepared and characterized by elemental and thermal analyses, molar conductance, magnetic susceptibility, infrared, NMR and electronic spectral studies. Some of the complexes were screened against E. coli, and Aspergillus niger for biological activity. The antibacterial activity of hydrazones and their complexes increases with increase of the concentration of solutions. At each concentration copper(II) complexes are more active than the Zinc(II) complexes with both hydrazones. The antifungal activity of the complexes is less than their parent ligands.