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    —— (6S)-6-N-cycloheptyl-2-N-(3-fluorophenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H28FN5O3
    (6S)-6-N-cycloheptyl-2-N-(3-fluorophenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cycloheptyl-2-N-[(3-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H30FN5O3
    (6S)-6-N-cycloheptyl-2-N-[(3-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclohexyl-5,6-dimethyl-4-oxo-2-N-[[(2R)-oxolan-2-yl]methyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H31N5O4
    (6S)-6-N-cyclohexyl-5,6-dimethyl-4-oxo-2-N-[[(2R)-oxolan-2-yl]methyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— 6-(2-hydroxy-3-methoxyphenyl)-8-(4-methylanilino)-2-(3-nitrophenyl)-6a-phenyl-4,6,9a,10,10a,10b-hexahydro-3aH-isoindolo[5,6-e]isoindole-1,3,7,9-tetrone —— C40H34N4O8
    6-(2-hydroxy-3-methoxyphenyl)-8-(4-methylanilino)-2-(3-nitrophenyl)-6a-phenyl-4,6,9a,10,10a,10b-hexahydro-3aH-isoindolo[5,6-e]isoindole-1,3,7,9-tetrone
    —— (6R)-6-N-cyclohexyl-5,6-dimethyl-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C22H34N6O4
    (6R)-6-N-cyclohexyl-5,6-dimethyl-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclohexyl-5,6-dimethyl-2-N-(3-methylsulfanylphenyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H29N5O3S
    (6S)-6-N-cyclohexyl-5,6-dimethyl-2-N-(3-methylsulfanylphenyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclohexyl-5,6-dimethyl-4-oxo-2-N-[[(2S)-oxolan-2-yl]methyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H31N5O4
    (6S)-6-N-cyclohexyl-5,6-dimethyl-4-oxo-2-N-[[(2S)-oxolan-2-yl]methyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclohexyl-2-N-[(2,5-dimethoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H33N5O5
    (6R)-6-N-cyclohexyl-2-N-[(2,5-dimethoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclohexyl-5,6-dimethyl-4-oxo-2-N-[(2S)-2-phenylpropyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H33N5O3
    (6R)-6-N-cyclohexyl-5,6-dimethyl-4-oxo-2-N-[(2S)-2-phenylpropyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclopentyl-5,6-dimethyl-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H32N6O4
    (6S)-6-N-cyclopentyl-5,6-dimethyl-2-N-(2-morpholin-4-ylethyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cycloheptyl-5,6-dimethyl-4-oxo-2-N-(pyridin-3-ylmethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H30N6O3
    (6R)-6-N-cycloheptyl-5,6-dimethyl-4-oxo-2-N-(pyridin-3-ylmethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclohexyl-2-N-[(3-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H28FN5O3
    (6R)-6-N-cyclohexyl-2-N-[(3-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclohexyl-2-N-[(3-methoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H31N5O4
    (6R)-6-N-cyclohexyl-2-N-[(3-methoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclohexyl-2-N-(4-ethylphenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H31N5O3
    (6S)-6-N-cyclohexyl-2-N-(4-ethylphenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cycloheptyl-2-N-[(3-methoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H33N5O4
    (6S)-6-N-cycloheptyl-2-N-[(3-methoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclohexyl-5,6-dimethyl-4-oxo-2-N-(3-propylsulfanylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C22H35N5O3S
    (6S)-6-N-cyclohexyl-5,6-dimethyl-4-oxo-2-N-(3-propylsulfanylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-2-N-[(2-bromophenyl)methyl]-6-N-cyclopentyl-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C22H26BrN5O3
    (6S)-2-N-[(2-bromophenyl)methyl]-6-N-cyclopentyl-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-2-(4-carbamoylpiperidine-1-carbonyl)-N-cycloheptyl-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C23H34N6O4
    (6R)-2-(4-carbamoylpiperidine-1-carbonyl)-N-cycloheptyl-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-6-N-cycloheptyl-2-N-(3-methoxyphenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H31N5O4
    (6R)-6-N-cycloheptyl-2-N-(3-methoxyphenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclopentyl-2-N-(3-methoxypropyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C19H29N5O4
    (6S)-6-N-cyclopentyl-2-N-(3-methoxypropyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— 6-[2-[5-(4-methoxyphenyl)-3-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]-2-oxoethyl]sulfanyl-1-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-one —— C30H26N6O3S
    6-[2-[5-(4-methoxyphenyl)-3-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]-2-oxoethyl]sulfanyl-1-phenyl-2H-pyrazolo[3,4-d]pyrimidin-4-one
    —— (6S)-6-N-cyclohexyl-5,6-dimethyl-4-oxo-2-N-[(2S)-2-phenylpropyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H33N5O3
    (6S)-6-N-cyclohexyl-5,6-dimethyl-4-oxo-2-N-[(2S)-2-phenylpropyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclohexyl-2-N-(3-fluorophenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C22H26FN5O3
    (6S)-6-N-cyclohexyl-2-N-(3-fluorophenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclohexyl-2-N-(3-ethylphenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H31N5O3
    (6S)-6-N-cyclohexyl-2-N-(3-ethylphenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclohexyl-2-N-[(2-methoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H31N5O4
    (6R)-6-N-cyclohexyl-2-N-[(2-methoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclopentyl-5,6-dimethyl-4-oxo-2-N-(3-propan-2-yloxypropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H33N5O4
    (6S)-6-N-cyclopentyl-5,6-dimethyl-4-oxo-2-N-(3-propan-2-yloxypropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclohexyl-2-N-(furan-2-ylmethyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H27N5O4
    (6R)-6-N-cyclohexyl-2-N-(furan-2-ylmethyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclohexyl-2-N-[2-(2,4-dimethoxyphenyl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H35N5O5
    (6S)-6-N-cyclohexyl-2-N-[2-(2,4-dimethoxyphenyl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclohexyl-2-N-[3-(4-ethylpiperazin-1-yl)propyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H41N7O3
    (6R)-6-N-cyclohexyl-2-N-[3-(4-ethylpiperazin-1-yl)propyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclohexyl-2-N-[2-(4-ethylpiperazin-1-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H39N7O3
    (6S)-6-N-cyclohexyl-2-N-[2-(4-ethylpiperazin-1-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclopentyl-5,6-dimethyl-2-N-(3-methylbutyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C20H31N5O3
    (6R)-6-N-cyclopentyl-5,6-dimethyl-2-N-(3-methylbutyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-2-N-cycloheptyl-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C22H35N5O3
    (6R)-2-N-cycloheptyl-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclohexyl-2-N-ethyl-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C18H27N5O3
    (6R)-6-N-cyclohexyl-2-N-ethyl-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cycloheptyl-5,6-dimethyl-4-oxo-2-N-[(2S)-2-phenylpropyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H35N5O3
    (6R)-6-N-cycloheptyl-5,6-dimethyl-4-oxo-2-N-[(2S)-2-phenylpropyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclohexyl-2-N-[(3,4-dimethoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H33N5O5
    (6R)-6-N-cyclohexyl-2-N-[(3,4-dimethoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclohexyl-5,6-dimethyl-4-oxo-2-N-(2-phenylethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H31N5O3
    (6S)-6-N-cyclohexyl-5,6-dimethyl-4-oxo-2-N-(2-phenylethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclohexyl-2-N-[(2-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H28FN5O3
    (6S)-6-N-cyclohexyl-2-N-[(2-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclohexyl-2-N-(2,4-dimethylphenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H31N5O3
    (6S)-6-N-cyclohexyl-2-N-(2,4-dimethylphenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclohexyl-2-N-(2,3-dimethylphenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H31N5O3
    (6R)-6-N-cyclohexyl-2-N-(2,3-dimethylphenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cycloheptyl-5,6-dimethyl-4-oxo-2-N-(pyridin-2-ylmethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H30N6O3
    (6R)-6-N-cycloheptyl-5,6-dimethyl-4-oxo-2-N-(pyridin-2-ylmethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclohexyl-2-N-(2,4-dimethylphenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H31N5O3
    (6R)-6-N-cyclohexyl-2-N-(2,4-dimethylphenyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclopentyl-2-N-[(4-methoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H29N5O4
    (6R)-6-N-cyclopentyl-2-N-[(4-methoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclohexyl-2-N-[2-(1H-indol-3-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H32N6O3
    (6S)-6-N-cyclohexyl-2-N-[2-(1H-indol-3-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclopentyl-2-N-(furan-2-ylmethyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C20H25N5O4
    (6R)-6-N-cyclopentyl-2-N-(furan-2-ylmethyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclohexyl-5,6-dimethyl-2-N-[(4-methylsulfanylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H31N5O3S
    (6R)-6-N-cyclohexyl-5,6-dimethyl-2-N-[(4-methylsulfanylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclohexyl-5,6-dimethyl-4-oxo-2-N-(thiophen-2-ylmethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H27N5O3S
    (6R)-6-N-cyclohexyl-5,6-dimethyl-4-oxo-2-N-(thiophen-2-ylmethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— 6-acetyl-2-[[4-(dipropylsulfamoyl)benzoyl]amino]-N-methyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide —— C24H32N4O5S2
    6-acetyl-2-[[4-(dipropylsulfamoyl)benzoyl]amino]-N-methyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide
    —— (6S)-6-N-cyclohexyl-2-N-[(1R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H33N5O5
    (6S)-6-N-cyclohexyl-2-N-[(1R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclopentyl-5,6-dimethyl-2-N-[3-(4-methylpiperazin-1-yl)propyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H37N7O3
    (6R)-6-N-cyclopentyl-5,6-dimethyl-2-N-[3-(4-methylpiperazin-1-yl)propyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cyclohexyl-2-N-[(2-ethoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H33N5O4
    (6S)-6-N-cyclohexyl-2-N-[(2-ethoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide