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    —— (6S)-2-N-[(2,5-dimethoxyphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H28FN5O5
    (6S)-2-N-[(2,5-dimethoxyphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-2-N-(3-ethoxypropyl)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C22H28FN5O4
    (6S)-2-N-(3-ethoxypropyl)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-2-N,6-N-dibenzyl-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H25N5O3
    (6S)-2-N,6-N-dibenzyl-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-benzyl-2-N-[2-(dimethylamino)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H28N6O3
    (6S)-6-N-benzyl-2-N-[2-(dimethylamino)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-2-(4-cyclohexylpiperazine-1-carbonyl)-5,6-dimethyl-N-(3-methylbutyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C25H40N6O3
    (6S)-2-(4-cyclohexylpiperazine-1-carbonyl)-5,6-dimethyl-N-(3-methylbutyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-2-N-(2-methoxyethyl)-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C18H29N5O4
    (6R)-2-N-(2-methoxyethyl)-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5,6-dimethyl-N-(3-methylbutyl)-4-oxo-2-(pyrrolidine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C19H29N5O3
    (6S)-5,6-dimethyl-N-(3-methylbutyl)-4-oxo-2-(pyrrolidine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-6-N-benzyl-2-N-[(4-ethoxy-3-methoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H31N5O5
    (6S)-6-N-benzyl-2-N-[(4-ethoxy-3-methoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-2-N-[(2,5-dimethoxyphenyl)methyl]-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H33N5O5
    (6S)-2-N-[(2,5-dimethoxyphenyl)methyl]-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-2-N-[(2-ethoxyphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H28FN5O4
    (6S)-2-N-[(2-ethoxyphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-N-benzyl-2-(4-ethylpiperazine-1-carbonyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C23H30N6O3
    (6S)-N-benzyl-2-(4-ethylpiperazine-1-carbonyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-2-N-[(3-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H26FN5O3
    (6S)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-2-N-[(3-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-2-N-[2-(diethylamino)ethyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H31FN6O3
    (6R)-2-N-[2-(diethylamino)ethyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-benzyl-2-N-[(4-ethylphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H29N5O3
    (6R)-6-N-benzyl-2-N-[(4-ethylphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5,6-dimethyl-6-N-(3-methylbutyl)-2-N-[(4-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H31N5O3
    (6R)-5,6-dimethyl-6-N-(3-methylbutyl)-2-N-[(4-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-2-N-[[4-(dimethylamino)phenyl]methyl]-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H34N6O3
    (6R)-2-N-[[4-(dimethylamino)phenyl]methyl]-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5,6-dimethyl-2-N,6-N-bis(3-methylbutyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C20H33N5O3
    (6S)-5,6-dimethyl-2-N,6-N-bis(3-methylbutyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-2-N-[(1R)-1-phenylethyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H31N5O3
    (6R)-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-2-N-[(1R)-1-phenylethyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-(piperidine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C22H26FN5O3
    (6R)-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-(piperidine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-2-N-(3-ethylphenyl)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H26FN5O3
    (6S)-2-N-(3-ethylphenyl)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-N-[(4-propan-2-yloxyphenyl)methyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H30FN5O4
    (6S)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-N-[(4-propan-2-yloxyphenyl)methyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-2-N-cyclohexyl-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H28FN5O3
    (6R)-2-N-cyclohexyl-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-benzyl-5,6-dimethyl-4-oxo-2-N-(pyridin-3-ylmethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H24N6O3
    (6R)-6-N-benzyl-5,6-dimethyl-4-oxo-2-N-(pyridin-3-ylmethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-N-benzyl-2-(4-benzylpiperidine-1-carbonyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C29H33N5O3
    (6S)-N-benzyl-2-(4-benzylpiperidine-1-carbonyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-2-N-[(2-ethoxyphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H28FN5O4
    (6R)-2-N-[(2-ethoxyphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-2-N-(2-phenylethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H31N5O3
    (6S)-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-2-N-(2-phenylethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5,6-dimethyl-6-N-[(4-methylphenyl)methyl]-4-oxo-2-N-(3-piperidin-1-ylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H36N6O3
    (6S)-5,6-dimethyl-6-N-[(4-methylphenyl)methyl]-4-oxo-2-N-(3-piperidin-1-ylpropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-[(4-fluorophenyl)methyl]-2-N-(3-methoxypropyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H26FN5O4
    (6R)-6-N-[(4-fluorophenyl)methyl]-2-N-(3-methoxypropyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-N-[(4-propan-2-yloxyphenyl)methyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H30FN5O4
    (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-N-[(4-propan-2-yloxyphenyl)methyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-[(4-fluorophenyl)methyl]-2-N-(3-methoxypropyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H26FN5O4
    (6S)-6-N-[(4-fluorophenyl)methyl]-2-N-(3-methoxypropyl)-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-N-[3-(2-oxopyrrolidin-1-yl)propyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H29FN6O4
    (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-N-[3-(2-oxopyrrolidin-1-yl)propyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-benzyl-2-N-[(3,4-dimethoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H29N5O5
    (6S)-6-N-benzyl-2-N-[(3,4-dimethoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-N-benzyl-5,6-dimethyl-2-(4-methylpiperidine-1-carbonyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C23H29N5O3
    (6S)-N-benzyl-5,6-dimethyl-2-(4-methylpiperidine-1-carbonyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-2-N-(2-pyrrolidin-1-ylethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H34N6O3
    (6S)-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-2-N-(2-pyrrolidin-1-ylethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-2-N-[(4-ethoxy-3-methoxyphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H30FN5O5
    (6R)-2-N-[(4-ethoxy-3-methoxyphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-2-N-[2-(dimethylamino)ethyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H27FN6O3
    (6R)-2-N-[2-(dimethylamino)ethyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-[(4-fluorophenyl)methyl]-2-N-[(2-methoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H26FN5O4
    (6S)-6-N-[(4-fluorophenyl)methyl]-2-N-[(2-methoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5,6-dimethyl-6-N-[(4-methylphenyl)methyl]-4-oxo-2-N-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H27N5O3
    (6R)-5,6-dimethyl-6-N-[(4-methylphenyl)methyl]-4-oxo-2-N-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-[(4-fluorophenyl)methyl]-2-N-[(3-methoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H26FN5O4
    (6S)-6-N-[(4-fluorophenyl)methyl]-2-N-[(3-methoxyphenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-2-N-[(2,3-dimethoxyphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H28FN5O5
    (6R)-2-N-[(2,3-dimethoxyphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5,6-dimethyl-N-(3-methylbutyl)-2-(morpholine-4-carbonyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C19H29N5O4
    (6S)-5,6-dimethyl-N-(3-methylbutyl)-2-(morpholine-4-carbonyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-6-N-benzyl-2-N-[2-(2,4-dimethoxyphenyl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H31N5O5
    (6R)-6-N-benzyl-2-N-[2-(2,4-dimethoxyphenyl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-cycloheptyl-2-N-[2-(cyclohexen-1-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H37N5O3
    (6S)-6-N-cycloheptyl-2-N-[2-(cyclohexen-1-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-2-N-[(2R)-2-phenylpropyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H33N5O3
    (6S)-5,6-dimethyl-6-N-(3-methylbutyl)-4-oxo-2-N-[(2R)-2-phenylpropyl]-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-benzyl-2-N-[(2-chlorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H24ClN5O3
    (6R)-6-N-benzyl-2-N-[(2-chlorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-2-N-[[4-(dimethylamino)phenyl]methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H29FN6O3
    (6S)-2-N-[[4-(dimethylamino)phenyl]methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-2-N-[(3,4-dimethoxyphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H28FN5O5
    (6S)-2-N-[(3,4-dimethoxyphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-2-N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)propyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C29H33FN6O3
    (6R)-2-N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)propyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-N-(3-propan-2-yloxypropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H30FN5O4
    (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-N-(3-propan-2-yloxypropyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-2-(4-methylpiperazine-1-carbonyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C22H27FN6O3
    (6S)-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-2-(4-methylpiperazine-1-carbonyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide