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    —— (6R)-5-butyl-6-N-cyclopentyl-6-methyl-2-N-(4-methylphenyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H33N5O3
    (6R)-5-butyl-6-N-cyclopentyl-6-methyl-2-N-(4-methylphenyl)-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5-butyl-6-N-cyclopentyl-6-methyl-4-oxo-2-N-(2-thiophen-2-ylethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H33N5O3S
    (6S)-5-butyl-6-N-cyclopentyl-6-methyl-4-oxo-2-N-(2-thiophen-2-ylethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5-butyl-6-N-cyclopentyl-2-N-(3-ethylphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H35N5O3
    (6S)-5-butyl-6-N-cyclopentyl-2-N-(3-ethylphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— 6-Amino-4-{3-[(2-methylbenzyl)oxy]phenyl}-3-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile —— C27H22N4O2
    6-Amino-4-{3-[(2-methylbenzyl)oxy]phenyl}-3-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
    —— 6-amino-3-propan-2-ylspiro[2H-pyrano[2,3-c]pyrazole-4,9'-fluorene]-5-carbonitrile —— C22H18N4O
    6-amino-3-propan-2-ylspiro[2H-pyrano[2,3-c]pyrazole-4,9'-fluorene]-5-carbonitrile
    —— (6S)-5-butyl-N-cyclopentyl-2-[4-(4-fluorophenyl)piperazine-1-carbonyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H37FN6O3
    (6S)-5-butyl-N-cyclopentyl-2-[4-(4-fluorophenyl)piperazine-1-carbonyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-2-N-[(2,5-dimethylphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H28FN5O3
    (6R)-2-N-[(2,5-dimethylphenyl)methyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5-butyl-N-cyclopentyl-6-methyl-4-oxo-2-(4-piperidin-1-ylpiperidine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H44N6O3
    (6R)-5-butyl-N-cyclopentyl-6-methyl-4-oxo-2-(4-piperidin-1-ylpiperidine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-5-butyl-N-cyclopentyl-6-methyl-4-oxo-2-(4-propylpiperazine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C25H40N6O3
    (6R)-5-butyl-N-cyclopentyl-6-methyl-4-oxo-2-(4-propylpiperazine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-5-butyl-6-N-cyclopentyl-2-N-[(3,4-dimethoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H37N5O5
    (6R)-5-butyl-6-N-cyclopentyl-2-N-[(3,4-dimethoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5-butyl-N-cyclopentyl-2-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C29H40N6O4
    (6R)-5-butyl-N-cyclopentyl-2-[4-(4-methoxyphenyl)piperazine-1-carbonyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-6-N-cyclopentyl-5-ethyl-6-methyl-2-N-[3-(4-methylpiperazin-1-yl)propyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H39N7O3
    (6R)-6-N-cyclopentyl-5-ethyl-6-methyl-2-N-[3-(4-methylpiperazin-1-yl)propyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-benzyl-2-N-[2-(1H-imidazol-5-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C22H25N7O3
    (6S)-6-N-benzyl-2-N-[2-(1H-imidazol-5-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5-butyl-6-N-cyclopentyl-2-N-[(3-methoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H35N5O4
    (6S)-5-butyl-6-N-cyclopentyl-2-N-[(3-methoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5-butyl-6-N-cyclopentyl-6-methyl-2-N-[(2-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H35N5O3
    (6S)-5-butyl-6-N-cyclopentyl-6-methyl-2-N-[(2-methylphenyl)methyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5-butyl-6-N-cyclopentyl-2-N-(2,5-dimethoxyphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H35N5O5
    (6S)-5-butyl-6-N-cyclopentyl-2-N-(2,5-dimethoxyphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-N-cyclopentyl-6-methyl-4-oxo-2-(4-phenylpiperazine-1-carbonyl)-5-propyl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C27H36N6O3
    (6S)-N-cyclopentyl-6-methyl-4-oxo-2-(4-phenylpiperazine-1-carbonyl)-5-propyl-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6S)-5-butyl-6-N-cyclopentyl-2-N-(2,5-difluorophenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H29F2N5O3
    (6S)-5-butyl-6-N-cyclopentyl-2-N-(2,5-difluorophenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5-butyl-6-N-cyclopentyl-2-N-(2,5-difluorophenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H29F2N5O3
    (6R)-5-butyl-6-N-cyclopentyl-2-N-(2,5-difluorophenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5-butyl-6-N-cyclopentyl-2-N-[(2,5-dimethoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H37N5O5
    (6S)-5-butyl-6-N-cyclopentyl-2-N-[(2,5-dimethoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5-butyl-6-N-cyclopentyl-2-N-[(4-ethoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H37N5O4
    (6S)-5-butyl-6-N-cyclopentyl-2-N-[(4-ethoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5-butyl-6-N-cyclopentyl-6-methyl-4-oxo-2-N-(thiophen-2-ylmethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C23H31N5O3S
    (6R)-5-butyl-6-N-cyclopentyl-6-methyl-4-oxo-2-N-(thiophen-2-ylmethyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5-butyl-6-N-cyclopentyl-2-N-(2-methoxyphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H33N5O4
    (6R)-5-butyl-6-N-cyclopentyl-2-N-(2-methoxyphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5-butyl-6-N-cyclopentyl-6-methyl-2-N-[2-(4-methylphenyl)ethyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H37N5O3
    (6S)-5-butyl-6-N-cyclopentyl-6-methyl-2-N-[2-(4-methylphenyl)ethyl]-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— [6-[[3-Hydroxy-1-[[1-hydroxy-5-[(2-methylpropan-2-yl)oxy]-5-oxopentan-2-yl]amino]-1-oxobutan-2-yl]carbamoyl]-3a,4,5,7a-tetrahydro-1,3-benzodioxol-4-yl] 4-[3-(4,4-dimethyl-2-oxooxolan-3-yl)oxy-3-oxoprop-1-enyl]benzoate —— C37H48N2O14
    [6-[[3-Hydroxy-1-[[1-hydroxy-5-[(2-methylpropan-2-yl)oxy]-5-oxopentan-2-yl]amino]-1-oxobutan-2-yl]carbamoyl]-3a,4,5,7a-tetrahydro-1,3-benzodioxol-4-yl] 4-[3-(4,4-dimethyl-2-oxooxolan-3-yl)oxy-3-oxoprop-1-enyl]benzoate
    —— (6S)-5-butyl-N-cyclopentyl-2-[4-(3-methoxyphenyl)piperazine-1-carbonyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C29H40N6O4
    (6S)-5-butyl-N-cyclopentyl-2-[4-(3-methoxyphenyl)piperazine-1-carbonyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-5-butyl-2-N-(2-chloro-4-methylphenyl)-6-N-cyclopentyl-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H32ClN5O3
    (6R)-5-butyl-2-N-(2-chloro-4-methylphenyl)-6-N-cyclopentyl-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5-butyl-6-N-cyclopentyl-2-N-(3-ethylphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H35N5O3
    (6R)-5-butyl-6-N-cyclopentyl-2-N-(3-ethylphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-2-N-[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H27FN6O4
    (6S)-2-N-[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-2-N-[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H27FN6O4
    (6R)-2-N-[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-6-N-benzyl-5,6-dimethyl-4-oxo-2-N-prop-2-enyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C20H23N5O3
    (6S)-6-N-benzyl-5,6-dimethyl-4-oxo-2-N-prop-2-enyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5-butyl-6-N-cyclopentyl-2-N-[2-(1H-indol-3-yl)ethyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C28H36N6O3
    (6R)-5-butyl-6-N-cyclopentyl-2-N-[2-(1H-indol-3-yl)ethyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-N-prop-2-enyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C20H22FN5O3
    (6R)-6-N-[(4-fluorophenyl)methyl]-5,6-dimethyl-4-oxo-2-N-prop-2-enyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5-butyl-6-N-cyclopentyl-6-methyl-4-oxo-2-N-(4-propan-2-ylphenyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H37N5O3
    (6R)-5-butyl-6-N-cyclopentyl-6-methyl-4-oxo-2-N-(4-propan-2-ylphenyl)-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5-butyl-6-N-cyclopentyl-2-N-[(2,4-dimethoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H37N5O5
    (6S)-5-butyl-6-N-cyclopentyl-2-N-[(2,4-dimethoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5-butyl-6-N-cyclopentyl-2-N-[(4-fluorophenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H32FN5O3
    (6S)-5-butyl-6-N-cyclopentyl-2-N-[(4-fluorophenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-benzyl-2-N-[2-(1H-imidazol-5-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C22H25N7O3
    (6R)-6-N-benzyl-2-N-[2-(1H-imidazol-5-yl)ethyl]-5,6-dimethyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5-butyl-6-N-cyclopentyl-2-N-(2-ethyl-6-methylphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H37N5O3
    (6R)-5-butyl-6-N-cyclopentyl-2-N-(2-ethyl-6-methylphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5-butyl-N-cyclopentyl-6-methyl-4-oxo-2-(4-piperidin-1-ylpiperidine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H44N6O3
    (6S)-5-butyl-N-cyclopentyl-6-methyl-4-oxo-2-(4-piperidin-1-ylpiperidine-1-carbonyl)-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide
    —— (6R)-5-butyl-6-N-cyclopentyl-2-N-[(4-ethylphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H37N5O3
    (6R)-5-butyl-6-N-cyclopentyl-2-N-[(4-ethylphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclopentyl-2-N-(3-methoxypropyl)-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C21H33N5O4
    (6R)-6-N-cyclopentyl-2-N-(3-methoxypropyl)-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5-butyl-6-N-cyclopentyl-2-N-[(2,5-dimethoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H37N5O5
    (6R)-5-butyl-6-N-cyclopentyl-2-N-[(2,5-dimethoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5-butyl-6-N-cyclopentyl-2-N-(2-methoxyphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C25H33N5O4
    (6S)-5-butyl-6-N-cyclopentyl-2-N-(2-methoxyphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclopentyl-6-methyl-4-oxo-2-N-(2-piperidin-1-ylethyl)-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C24H38N6O3
    (6R)-6-N-cyclopentyl-6-methyl-4-oxo-2-N-(2-piperidin-1-ylethyl)-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-benzyl-5,6-dimethyl-4-oxo-2-N-prop-2-enyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C20H23N5O3
    (6R)-6-N-benzyl-5,6-dimethyl-4-oxo-2-N-prop-2-enyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclopentyl-2-N-[(4-ethoxy-3-methoxyphenyl)methyl]-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H37N5O5
    (6R)-6-N-cyclopentyl-2-N-[(4-ethoxy-3-methoxyphenyl)methyl]-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6S)-5-butyl-6-N-cyclopentyl-2-N-(3,5-dimethoxyphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H35N5O5
    (6S)-5-butyl-6-N-cyclopentyl-2-N-(3,5-dimethoxyphenyl)-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-6-N-cyclopentyl-2-N-[(2,3-dimethoxyphenyl)methyl]-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C26H35N5O5
    (6R)-6-N-cyclopentyl-2-N-[(2,3-dimethoxyphenyl)methyl]-6-methyl-4-oxo-5-propyl-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5-butyl-6-N-cyclopentyl-2-N-[(2-ethoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide —— C27H37N5O4
    (6R)-5-butyl-6-N-cyclopentyl-2-N-[(2-ethoxyphenyl)methyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-2,6-dicarboxamide
    —— (6R)-5-butyl-N-cyclopentyl-2-[4-(4-fluorophenyl)piperazine-1-carbonyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide —— C28H37FN6O3
    (6R)-5-butyl-N-cyclopentyl-2-[4-(4-fluorophenyl)piperazine-1-carbonyl]-6-methyl-4-oxo-7H-pyrazolo[1,5-a]pyrazine-6-carboxamide