对照品
对照品
对照品是指用于药物研究和分析中作为标准参照物质的纯化化学物质或混合物。在有机化学、化学化工以及生物医药领域中，对照品具有重要的应用价值。它们常被用来确保实验的一致性和可靠性，特别是在定量分析、定性鉴定、药效评价及质量控制等方面。
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用途
- 药物开发：在新药研发过程中，对照品用于确定化合物的结构、纯度和活性。
- 质控检测：作为标准参照物，在药品生产过程中的各个阶段进行质量监控。
- 分析方法验证：确保分析方法的有效性和准确性。
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类型
- 天然产物：从生物来源提取的对照品，如植物、微生物等。
- 合成化合物：通过化学合成制备的标准物质。
- 标准溶液：用以配制特定浓度的对照品溶液，便于定量分析使用。
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获取方式
- 商业购买：市面上有许多供应商提供各种类型的对照品。
- 自制：科研机构或实验室可根据需要自行合成。
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重要性
- 确保实验数据的真实性和准确性是科学研究的基础。对照品的准确性和可靠性直接关系到研究结果的质量。
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注意事项
- 对照品应存储在适宜条件下，避免受潮、光照等外界因素影响其纯度和稳定性。
- 在使用过程中应注意核对批号与质量规格信息，确保使用的对照品符合实验需求。
| 中文名称 | 英文名称 | CAS号 | 化学式 |
|---|---|---|---|
| (3R,7AS)-四氢-3-苯基-3H,5H-吡咯并[1,2-C]噁唑-5-酮 | hydroxy-α-sanshool | 83883-10-7 | C16H25NO2 |
| (3R,4S,5S,6R,7R,9R,11R,12S,13R,14R)-4-[(2R,4R,5R,6S)-4,5-二羟基-4,6-二甲基四氢吡喃-2-基]氧基-6-[(2S,3R,4S,6R)-4-二甲基氨基-3-羟基-6-甲基四氢吡喃-2-基]氧基-14-乙基-7,12-二羟基-3,5,7,9,11,13-六甲基-1-氧杂环十四烷-2,10-二酮 | Erythromycin, 3''-O-demethyl-12-deoxy- | 33442-56-7 | C36H65NO12 |
| (2β,3α,5α,8xi,9xi,14xi,16β,17β)-3-(乙酰氧基)-17-羟基-16-(1-甲基哌啶正离子-1-基)-2-(哌啶-1-基)雄甾烷溴化 | 17-Deacetyl vecuronium bromide | 50587-95-6 | C32H55BrN2O3 |
| (2b,3a,5a,16b,17b)-17-乙酰氧基-3-羟基-2-(4-吗啉基)-16-(1-吡咯烷基)雄甾烷 | 2β-(4-morpholinyl)-16β-(1-pyrrolidinyl)-5α-androstan-3α-ol, 17β-acetate | 119302-24-8 | C29H48N2O4 |
| (2S,5R,6R)-6-{[(2S)-2-氨基-2-苯基乙酰基]氨基}-3,3-二甲基-7-氧代-4-硫杂-1-氮杂双环[3.2.0]庚烷-2-羧酸 | ampicillin | 19379-33-0 | C16H19N3O4S |
| (2S,5R)-5-[(苯基甲氧基)氨基]-2-哌啶羧酸乙酯草酸盐 | ethyl (2S,5R)-5-((benzyloxy)amino)piperidine-2-carboxylate oxalate | 1416134-48-9 | C2H2O4*C15H22N2O3 |
| (20S)-3beta-乙酰氧基孕甾-5-烯-20-甲醛 | (3beta,20S)-20-Formyl-3-hydroxy-5-pregnene 3-O-Acetate | 10211-88-8 | C24H36O3 |
| (1S,3S)-1-(1,3-苯并二氧戊环-5-基)-2,3,4,9-四氢-1H-吡啶并[3,4-b]吲哚-3-羧酸甲酯 | methyl (1S,3S)-1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate | 171596-43-3 | C20H18N2O4 |
| (1S,2S,3S,4R)-3-[(1S)-1-氨基-2-乙基丁基]-4-[叔丁氧羰基氨基]-2-羟基-环戊烷羧酸甲酯 | (1S,2S,3S,4R)-Methyl 3-((R)-1-amino-2-ethylbutyl)-4-((tert-butoxycarbonyl)amino)-2-hydroxycyclopentanecarboxylate | 316173-29-2 | C18H34N2O5 |
| (1E)-N-羟基-5-甲氧基-1-[4-(三氟甲基)苯基]-1-戊烷亚胺 | (1E)-N-hydroxy-5-methoxy-1-(4-trifluoromethyl phenyl)pentan-1-imine | 61747-22-6 | C13H16F3NO2 |
| (13alpha,14beta,17alpha,20S)-5alpha-羊毛甾-8,24-二烯-3beta-醇 | tirucallol | 514-46-5 | C30H50O |
| (10E)-10,11-二去氢-11-脱氧-6-O-甲基红霉素 | (10E)-10,11-ene-11-deoxy-clarithromycin | 144604-03-5 | C38H67NO12 |
| (-)-α-侧柏酮 | (-)-α-thujone | 546-80-5 | C10H16O |
| —— | 5-Amino-N1,N3-bis(2,3-dihydroxypropyl)-2,4-diiodoisophthalamide | 1215856-35-1 | C14H19I2N3O6 |
| —— | 12-epi-teucrin | 51918-98-0 | C19H20O5 |
| —— | Aztreonam Amide | 1219444-93-5 | C13H20N6O8S2 |
| —— | 3-(2-Methylpropyl)piperidine-2,6-dione | 916982-10-0 | C9H15NO2 |
| —— | Lysergol | 478-93-3 | C16H18N2O |
| —— | (20R,S)-3β-acetoxy-23,24-dinorchol-5-en-22-al | 10211-88-8 | C24H36O3 |
| —— | [10,13-dimethyl-17-(1-oxopropan-2-yl)-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate | 10211-88-8 | C24H36O3 |
| —— | ethyl 2-(3-aldoxime-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate | 1271738-74-9 | C18H22N2O4S |
| —— | 1-((2-(2-Methoxyphenoxy)ethyl)(methyl)amino)-3-((9-methyl-9H-carbazol-4-yl)oxy)propan-2-ol | 1479052-24-8 | C26H30N2O4 |
| —— | 9-chloro-6α-fluoro-11,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione | 1355648-15-5 | C22H28ClFO5 |
| —— | N-methyl-3-phenyl-(m-methylphenoxy)propylamine hydrochloride | 873310-28-2 | C17H21NO*ClH |
| —— | 6β-hydroxyprogesterone | 604-19-3 | C21H30O3 |
| —— | 1-{(2xi)-5-O-[Hydroxy({[2-(trimethylazaniumyl)ethoxy]phosphinato}oxy)phosphoryl]-beta-D-threo-pentofuranosyl}pyrimidine-2,4(1H,3H)-dione | 99492-83-8 | C14H25N3O12P2 |
| —— | 1-((2S,3S,5S,10S,13S,16S,17R)-3-Acetoxy-17-hydroxy-10,13-dimethyl-2-piperidin-1-yl-hexadecahydro-cyclopenta[a]phenanthren-16-yl)-1-methyl-piperidinium; bromide | 50587-95-6 | Br*C32H55N2O3 |
| —— | 21-Norrapamycin | 156223-31-3 | C50H77NO13 |
| —— | 16-(1-Methylpiperidin-1-ium-1-yl)-2-(piperidin-1-yl)androstane-3,17-diol bromide | 73319-30-9 | C30H53BrN2O2 |
| —— | amine | 366020-68-0 | C31H34N4O8S |
| —— | 21-dehydrobudesonide | 85234-63-5 | C25H32O6 |
| —— | N-(1-oxo-4-nitroisoindolin-2-yl)-L-glutamine | 874760-71-1 | C13H13N3O6 |
| —— | (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1S,2R)-1-hydroxy-2-methylhexyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone | 59865-15-5 | C62H113N11O12 |
| —— | Substance P, prolyl(2)-tryptophan(7,9)- | 80434-86-2 | C74H106N20O13S |
| —— | Benzamide, monohydrochloride, (+-)- | 911-77-3 | C19H22ClN6O4- |
| —— | [(2S,3R,4R,5S,6R)-2-{[(2R,3S,4R,5R,6R)-5-acetamido-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]carbamic acid | 577-76-4 | C15H26N2O12 |
| —— | (S)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)-benzonitrile Di-p-toluoyl-D-tartrate Salt (2:1) | 128173-53-5 | C60H64F2N4O12 |
| —— | (2R,4R,6S,11R,12S,15R,18S,20S,21R,23S,26S)-15-hydroxy-11,18,21-trimethyl-5,17,24,28,29-pentaoxanonacyclo[17.9.1.11,20.02,12.04,6.06,11.015,19.018,23.021,26]triacont-8-ene-10,16,25,30-tetrone | 57423-71-9 | C28H30O10 |
| —— | 9,10-Didehydro-6-methyl-8-hydroxymethylergoline | 602-85-7 | C16H18N2O |
| —— | Ergoline-8-beta-methanol, 1,6-dimethyl-10-methoxy- | 35155-28-3 | C18H24N2O2 |
| —— | tenuifoliside A | 139726-35-5 | C31H38O17 |
| —— | 7-(Thienyl-2-acetylamino)-3-methylcephamcarbonsaeure-4 | 34691-02-6 | C14H14N2O4S2 |
| —— | 4,4'-bis(dimethylsilyl)biphenyl | 17937-85-8 | C16H22Si2 |
| —— | O(3)-Kaffeoyl-shikimisaeure | 73263-62-4 | C16H16O8 |
| —— | d-tirucallol | 514-46-5 | C30H50O |
| —— | p-methoxybenzyl p-(p-methoxybenzyl)oxyphenylmalonic acid | 70175-90-5 | C25H24O7 |
| —— | physalin J | 57423-71-9 | C28H30O10 |
| —— | (10-methoxy-1,6-dimethyl-ergolin-8ξ-yl)-methanol | 35155-28-3 | C18H24N2O2 |
| —— | [2-[2-Chloro-1-[(1-methyl-4-propylpyrrolidine-2-carbonyl)amino]propyl]-3,5-dihydroxy-6-methylsulfanyloxan-4-yl] dihydrogen phosphate | 28708-34-1 | C18H34ClN2O8PS |
| —— | Desmethyltofacitinib | 1527525-58-1 | C15H18N6O |
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