2-hydroxybenzyl(α-N-butylamino)phosphonic acid | 61146-22-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-hydroxybenzyl(α-N-butylamino)phosphonic acid
• CAS: 61146-22-3
• 化学式: C₁₁H₁₈NO₄P
• 分子量: 259.242
• InChiKey: ZFDJYRNYHONVPM-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  2-hydroxybenzyl(α-N-butylamino)phosphonic acid 在 sodium hydroxide 作用下， 反应 5.0h， 以40%的产率得到3-Butylamino-2-oxo-2,3-dihydro-2λ⁵-benzo[d][1,2]oxaphosphol-2-ol
  参考文献：
  名称：

  A CLEAVAGE OF SOME HYDROXYBENZYL(α-AMINO)-PHOSPHONATES IN A BASIC MEDIUM

  摘要：

  alpha -Aminobenzylphosphonic acids possessing the hydroxy groups in ortho and para positions, underwent a C-P bond cleavage during heating with aqueous NaOH solution. In the case of o- and p-hydroxy diethyl esters 1 and 3 the products of the cleavage were the corresponding aldehydes and phosphorous acid (H3PO3). The m-hydroxy derivative was not affected by a base. It has been found, that displacement of the hydroxy group by the methoxy one in the p-hydroxybenzyl(alpha -amino)phosphonic acid leads to a stability of such a compound towards a base; no a C-P bond cleavage was observed in this case.

  DOI：

  10.1080/10426509808045493