| 1350289-99-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• CAS: 1350289-99-4
• 化学式: C₁₅H₁₆O₄
• 分子量: 260.29
• InChiKey: ATWFLKPYYSDFDQ-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  在 copper dichloride 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 2.0h， 生成 、 3-ethoxycarbonyl-2-(2,5-dimethoxyphenyl)-2,5-dihydrofuran
  参考文献：
  名称：

  Copper-Catalyzed Intramolecular Hydroalkoxylation of α-(1-Hydroxy-1-alkyl- and -aryl)methylallenoates by a 5-Endo Mode for Preparation of 2-Alkyl- and 2-Aryl-2,5-dihydrofurans

  摘要：

  Ethyl alpha-(1-hydroxy-1-alkyl)methylallenoates and alpha-(1-hydroxy-1-aryl)methylallenoates containing not only electron-donating groups but also an electron-withdrawing group on the aryl group at the alpha-position have been shown to undergo an efficient and selective copper-catalyzed intramolecular hydroalkoxylation to give functionalized 3-ethoxycarbony1-2-alkyl- and -aryl-2,5-dihydrofurans in good to excellent yields through a 5-endo mode.

  DOI：

  10.1021/jo2018125