(S)-HOC6H4CHNCH(Me)Ph | 1178971-29-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: (S)-HOC6H4CHNCH(Me)Ph
• CAS: 1178971-29-3
• 化学式: C₁₅H₁₅NO
• 分子量: 225.29
• InChiKey: AXTCKYFETKBZLF-LBPRGKRZSA-N

反应信息

• 作为反应物：
  描述：

  (S)-HOC6H4CHNCH(Me)Ph 、 二苯基氯化膦 、 palladium dichloride 在 (C₂H₅)3N 作用下， 以 甲苯 为溶剂， 以48%的产率得到[(2,6-(S)-(Ph2PO)C6H3(CHNCH(Me)Ph))PdCl]
  参考文献：
  名称：

  Facile synthesis of achiral and chiral PCN pincer palladium(II) complexes and their application in the Suzuki and copper-free Sonogashira cross-coupling reactions

  摘要：

  Five non-symmetrical PCN pincer palladium(II) complexes [PdCl{C6H3-2-(CH=NR)-6-(OPR'(2))}] (R = m-ClC6H4, R' = Ph (2a); R = Ph, R' = Ph (2b); R = i-Pr, R' = Ph (2c); R = m-ClC6H4, R' = i-Pr (2d); R = (S)-1-phenylethyl, R' = Ph (2e)) have been easily prepared in only two steps from readily available m-hydroxybenzaldehyde and characterized by HRMS, H-1 NMR, C-13 NMR, P-31 NMR and IR spectra. The molecular structures of 2a and 2b have been further determined by X-ray single-crystal diffraction. The obtained Pd complexes were found to be effective catalysts for the Suzuki and copper-free Sonogashira cross-coupling reactions which could be carried out in the undried solvent under air. (C) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2009.04.002
• 作为产物：
  描述：

  (S)-(-)- α-甲基苄胺 、 间羟基苯甲醛 在 aluminum oxide 作用下， 以 甲苯 为溶剂， 以82%的产率得到(S)-HOC6H4CHNCH(Me)Ph
  参考文献：
  名称：

  Facile synthesis of achiral and chiral PCN pincer palladium(II) complexes and their application in the Suzuki and copper-free Sonogashira cross-coupling reactions

  摘要：

  Five non-symmetrical PCN pincer palladium(II) complexes [PdCl{C6H3-2-(CH=NR)-6-(OPR'(2))}] (R = m-ClC6H4, R' = Ph (2a); R = Ph, R' = Ph (2b); R = i-Pr, R' = Ph (2c); R = m-ClC6H4, R' = i-Pr (2d); R = (S)-1-phenylethyl, R' = Ph (2e)) have been easily prepared in only two steps from readily available m-hydroxybenzaldehyde and characterized by HRMS, H-1 NMR, C-13 NMR, P-31 NMR and IR spectra. The molecular structures of 2a and 2b have been further determined by X-ray single-crystal diffraction. The obtained Pd complexes were found to be effective catalysts for the Suzuki and copper-free Sonogashira cross-coupling reactions which could be carried out in the undried solvent under air. (C) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2009.04.002