| 351514-63-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并二恶烷
• CAS: 351514-63-1
• 化学式: C₁₄H₁₂N₂O₄
• 分子量: 272.26
• InChiKey: PXCSAOKKRUBMQT-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  2-呋喃甲酰肼 、 1,4-苯并二恶烷-6-甲醛 在 甲酸 作用下， 以 二甲基亚砜 为溶剂， 生成
  参考文献：
  名称：

  Mechanistic differences between in vitro assays for hydrazone-based small molecule inhibitors of anthrax lethal factor

  摘要：

  A systematically generated series of hydrazones were analyzed as potential inhibitors of anthrax lethal factor. The hydrazones were screened using one UV-based and two fluorescence-based in vitro assays. The study identified several inhibitors with IC50 values in the micromolar range, and importantly, significant differences in the types of inhibition were observed with the different assays. (c) 2006 Elsevier Inc. All rights reserved.

  DOI：

  10.1016/j.bioorg.2006.07.004