胍苯克生 | 19889-45-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并二恶烷
• 中文名称: 胍苯克生
• 中文别名: 胍秉克沙
• 英文名称: Guabenxan
• 英文别名: 2-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)guanidine
• CAS: 19889-45-3
• 化学式: C₁₀H₁₃N₃O₂
• mdl: MFCD00865971
• 分子量: 207.23
• InChiKey: WTDYJDLUNYALPM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  82.9
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Pharmaceutical preparation comprising an active dispersed on a matrix
  申请人：——

  公开号：US20040058896A1

  公开（公告）日：2004-03-25

  The present invention relates to the field of pharmaceutical technology and describes a novel advantageous preparation for an active ingredient. The novel preparation is suitable for producing a large number of pharmaceutical dosage forms. In the new preparation an active ingredient is present essentially uniformly dispersed in an excipient matrix composed of one or more excipients selected from the group of fatty alcohol, triglyceride, partial glyceride and fatty acid ester.

  本发明涉及制药技术领域，描述了一种新的有利的活性成分制备方法。这种新的制备方法适用于生产大量的药物剂型。在这种新的制备方法中，活性成分基本上均匀地分散在由脂肪醇、甘油三酯、部分甘油酯和脂肪酸酯等多种赋形剂中选择的一种或多种赋形剂组成的赋形剂基质中。
• Diagnostic/therapeutic agents
  申请人：Klaveness Jo

  公开号：US20050002865A1

  公开（公告）日：2005-01-06

  Targetable diagnostic and/or therapeutically active agents, e.g. ultrasound contrast agents, comprising a suspension in an aqueous carrier liquid of a reporter comprising gas-containing or gas-generating material, said agent being capable of forming at least two types of binding pairs with a target.

  可定位的诊断和/或治疗活性剂，例如超声对比剂，包括悬浮在水载体液中的报告物，该报告物包含含气体或生成气体的材料，该剂能够与目标形成至少两种结合对。
• SUSPENSION FORMULATIONS
  申请人：Lewis David Andrew

  公开号：US20110182997A1

  公开（公告）日：2011-07-28

  The present invention relates to suspension formulations, especially those for delivering a pharmaceutically active agent in aerosol form using a spray or aerosol device, such as a pressurised metered dose inhaler (pMDI). The formulations may be for pulmonary, nasal, buccal or topical administration, but are preferably for pulmonary inhalation.

  本发明涉及悬浮液配方，特别是用于使用喷雾或气雾装置以气雾形式传递药物活性剂的配方，例如压力计量剂量吸入器（pMDI）。这些配方可以用于肺部、鼻部、颊部或局部给药，但最好用于肺部吸入。
• TAURINE COMPOSITIONS SUITABLE FOR INHALATION
  申请人：VECTURA LIMITED

  公开号：US20160051473A1

  公开（公告）日：2016-02-25

  The invention discloses spray-dried compositions for inhalation and methods for preparing such powder compositions. The compositions of the invention are produced by spray-drying taurine under conditions that (i) retain the physical and chemical stability of the composition during spray drying and upon storage, (ii) protect the powder composition from aggregation and (iii) provide particles suitable for aerosolisation.

  本发明公开了用于吸入的喷雾干燥组合物以及制备这种粉末组合物的方法。本发明的组合物是通过在保持组合物在喷雾干燥和储存期间的物理和化学稳定性，保护粉末组合物免受聚集，并为气溶胶化提供适当的颗粒的条件下，喷雾干燥牛磺酸而制成的。
• Inhaler
  申请人：Vectura Delivery Devices Limited

  公开号：EP2082767A1

  公开（公告）日：2009-07-29

  An inhaler (1) is disclosed. It comprises a housing (2) to receive a strip (3) having a surface (3a) and a plurality of blister pockets (5) depending from said surface. Each blister pocket contains a dose of medicament for inhalation by a user. The inhaler has a blister strip drive mechanism (7) including a blister strip drive member (27) shaped to contact the strip along a line defined by the crease (30) between a blister pocket and said surface, to drive said strip.

  本发明公开了一种吸入器（1）。它包括一个外壳（2），用于容纳一个具有表面（3a）的条状物（3）和多个与所述表面相连的水泡袋（5）。每个水泡袋中装有一定剂量的药物，供使用者吸入。吸入器有一个泡罩条驱动机构（7），包括一个泡罩条驱动部件（27），其形状是沿着泡罩袋和所述表面之间的折痕（30）所确定的线接触泡罩条，以驱动所述泡罩条。