5-hexyloxy-2-[4-hydroxyphenyl]pyrimidine | 105744-11-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 5-hexyloxy-2-[4-hydroxyphenyl]pyrimidine
• 英文别名: 5-Hexyloxy-2-(4-hydroxyphenyl)pyrimidine；4-(5-hexoxypyrimidin-2-yl)phenol
• CAS: 105744-11-4
• 化学式: C₁₆H₂₀N₂O₂
• 分子量: 272.347
• InChiKey: TUXVPVHPCFHANW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  20
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  55.2
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  5-hexyloxy-2-[4-hydroxyphenyl]pyrimidine 生成 5-Hexyloxy-2-[4-((R)-2-fluoro-3-(2-(2-(nonafluorobutoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)propoxy)phenyl]pyrimidine
  参考文献：
  名称：

  Liquid crystal compounds having a chiral fluorinated terminal portion

  摘要：

  含氟手性液晶化合物由以下组成：(a) 手性氟化学末端部分，包含至少一个亚甲基基团，并可选地包含至少一个链醚氧原子；(b) 饱和的手性或非手性烃末端部分；以及(c) 连接末端部分的中心核心。这些化合物具有液晶相或潜在液晶相，并可用于液晶显示器等领域。

  公开号：

  US05702637A1

文献信息

• Process for controlling cone tilt angle in mixtures of smectic liquid
  申请人：Minnesota Mining and Manufacturing Company

  公开号：US05928562A1

  公开（公告）日：1999-07-27

  A process for controlling the cone tilt angle of a tilted smectic liquid crystal composition comprises the step of combining (a) at least one liquid crystal composition comprising at least one smectic or latent smectic liquid crystal compound comprising (i) an aliphatic fluorocarbon terminal portion comprising a terminal fluoroalkyl or fluoroether group and an alkylene group having at least two carbon atoms and containing at least one catenary ether oxygen atom, (ii) an aliphatic hydrocarbon terminal portion, and (iii) a central core connecting the terminal portions; and (b) at least one liquid crystal composition comprising at least one smectic or latent smectic liquid crystal compound; with the provisos that at least one of the compositions (a) and (b) comprises at least one chiral liquid crystal compound and that the combining of compositions (a) and (b) provides an optically active, tilted chiral smectic liquid crystal composition. The process enables control of cone tilt angle and thereby control of the brightness characteristics of liquid crystal display devices.

  一种用于控制倾斜相液晶组合物锥倾角的方法包括以下步骤：将（a）至少一种包含至少一种含有至少一种脂肪氟碳末端部分的倾斜相或潜在倾斜相液晶化合物的液晶组合物与（i）末端氟烷基或氟醚基团和至少含有两个碳原子的烷基团并且含有至少一个链状醚氧原子的烷基团，（ii）脂肪烃末端部分和（iii）连接末端部分的中心核心；以及（b）至少一种包含至少一种倾斜相或潜在倾斜相液晶化合物的液晶组合物相结合的步骤；但要求至少其中一种组合物（a）和（b）包含至少一种手性液晶化合物，并且组合物（a）和（b）的结合提供了一种光学活性的、倾斜的手性相液晶组合物。该方法使得能够控制锥倾角，从而控制液晶显示设备的亮度特性。
• Compounds and process for controlling cone tilt angle in mixtures of
  申请人：Minnesota Mining and Manufacturing Company

  公开号：US05855812A1

  公开（公告）日：1999-01-05

  A process for controlling the cone tilt angle of a tilted smectic liquid crystal composition comprises the step of combining (a) at least one liquid crystal composition comprising at least one smectic or latent smectic liquid crystal compound comprising (i) an aliphatic fluorocarbon terminal portion comprising a terminal fluoroalkyl or fluoroether group and an alkylene group having at least two carbon atoms and containing at least one catenary ether oxygen atom, (ii) an aliphatic hydrocarbon terminal portion, and (iii) a central core connecting the terminal portions, wherein the alkylene group of the aliphatic fluorocarbon terminal portion is directly linked to the central core by a moiety selected from the group consisting of a covalent bond, --CH.dbd.CH--, and --C.tbd.C--; and (b) at least one liquid crystal composition comprising at least one smectic or latent smectic liquid crystal compound; with the provisos that at least one of the compositions (a) and (b) comprises at least one chiral liquid crystal compound and that the combining of compositions (a) and (b) provides an optically active, tilted chiral smectic liquid crystal composition. The process enables control of cone tilt angle and thereby control of the brightness characteristics of liquid crystal display devices.

  控制倾斜液晶体组合物的锥倾角的过程包括以下步骤：将（a）至少包括一种液晶组合物，该组合物包括至少一种含有（i）末端含有末端氟烷基或氟醚基团和至少两个碳原子的烷基团，并且含有至少一个链间醚氧原子的脂肪族氟碳末端部分，（ii）脂肪族烃末端部分和（iii）连接末端部分的中央核的液晶或潜在液晶化合物，其中烷基团直接通过从群组中选择的一个基团与中央核相连，该群组由共价键，-CH = CH-和-C.tbd.C-组成；以及（b）至少包括一种液晶组合物，该组合物包括至少一种液晶或潜在液晶化合物；但必须满足至少其中一种组合物（a）和（b）包括至少一种手性液晶化合物，并且（a）和（b）的组合提供了一种具有光学活性的倾斜手性液晶组合物。该过程使得锥倾角得以控制，从而控制液晶显示器件的亮度特性。
• LIQUID CRYSTAL COMPOUNDS HAVING A CHIRAL FLUORINATED TERMINAL PORTION
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0821719A1

  公开（公告）日：1998-02-04
• PROCESS FOR CONTROLLING CONE TILT ANGLE IN MIXTURES OF SMECTIC LIQUID CRYSTAL COMPOUNDS
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0868501B1

  公开（公告）日：2003-08-13
• COMPOUNDS AND PROCESS FOR CONTROLLING CONE TILT ANGLE IN MIXTURES OF SMECTIC LIQUID CRYSTAL COMPOUNDS
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0973844B1

  公开（公告）日：2003-06-04