3-吡啶甲腈,5-氨基-2-甲氧基-6-甲基- | 89079-38-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 单宁
• 中文名称: 3-吡啶甲腈,5-氨基-2-甲氧基-6-甲基-
• 英文名称: 2-O-(2,4,6-trihydroxyphenyl)-6,6'-bieckol
• 英文别名: 4-(3,5-dihydroxyphenoxy)-9-[6-(3,5-dihydroxyphenoxy)-2,4,9-trihydroxy-7-(2,4,6-trihydroxyphenoxy)dibenzo-p-dioxin-1-yl]dibenzo-p-dioxin-1,3,6,8-tetrol
• CAS: 89079-38-9
• 化学式: C₄₂H₂₆O₂₁
• 分子量: 866.656
• InChiKey: YHMKGQNHXHEHMW-UHFFFAOYSA-N

物化性质

• 密度：
  1.876±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  63
• 可旋转键数：
  7
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  348
• 氢给体数：
  14
• 氢受体数：
  21

反应信息

• 作为反应物：
  描述：

  3-吡啶甲腈,5-氨基-2-甲氧基-6-甲基- 、 乙酸酐 在 吡啶 作用下， 反应 20.0h， 以110 mg的产率得到2-O-(2,4,6-trihydroxyphenyl)-6,6'-bieckol tetradecaacetate
  参考文献：
  名称：

  Anti-plasmin inhibitor. V. Structures of novel dimeric eckols isolated from the brown alga Ecklonia kurome Okamura.

  摘要：

  6, 6'-Bieckol (1), 2-O-(2, 4, 6-trihydroxyphenyl)-6, 6'-bieckol (4), and 8, 8'-bieckol (2), bispolyphenols with a dibenzo-1, 4-dioxin skeleton, have been isolated as potent anti-plasmin inhibitors from the brown alga Ecklonia kurome OKAMURA. Their structures have been determined to be dimers of eckol linked at the C-6 or C-8 positions, through an aryl-aryl bond on the basis of spectral data. Their inhibitory actions on anti-plasmins (α2-macroglobulin and α2-plasmin inhibitor) and some proteases have been examined.

  DOI：

  10.1248/cpb.37.2438

文献信息

• FUKUYAMA, YOSHIYASU;KODAMA, MITSUAKI;MIURA, IWAO;KINZYO, ZIUNEI;MORI, HID+, CHEM. AND PHARM. BULL., 37,(1989) N, C. 2438-2440
  作者：FUKUYAMA, YOSHIYASU、KODAMA, MITSUAKI、MIURA, IWAO、KINZYO, ZIUNEI、MORI, HID+

  DOI：——

  日期：——
• METHOD FOR PREPARING INDUCED PLURIPOTENCY STEM CELLS FROM MESENCHYMAL STEM CELLS BY USING PHLOROTANNIN FRACTION
  申请人：BBHC

  公开号：US20170107481A1

  公开（公告）日：2017-04-20

  The present invention relates to a medium composition for the dedifferentiation of induced pluripotency stem cells, containing a phlorotannin fraction extracted and isolated from one type of brown algae selected from the group consisting of Ecklonia cava, Dictyopteris prolifera, Dictyota coriacea, Sargassum horneri, Ishige okamurai and the like. In addition, the present invention relates to a method for preparing induced pluripotency stem cells by using the medium composition. Induced pluripotency stem cells can be safely, easily and effectively prepared by using mesenchymal stem cells by using the medium composition of the present invention, and the prepared induced pluripotency stem cells can be differentiated into various cells, and thus can be useful as a cell therapeutic agent.
• BEVERAGE COMPOSITION COMPRISING PHLOROTANNIN, GINSENG EXTRACT AND CAFFEINE
  申请人：BOTAMEDI INC.

  公开号：US20170119772A1

  公开（公告）日：2017-05-04

  A beverage composition comprising phlorotannin, a ginseng extract and caffeine, and being effective in improving work performance, such as improving concentration and fatigue, preventing sleepiness, relieving hangovers, reducing headaches and improving physical abilities.
• COMPOSITION FOR IMPROVING FLAVOR OF FOOD, CONTAINING PHLOROTANNIN AS ACTIVE INGREDIENT
  申请人：BOTAMEDI INC.

  公开号：US20220015403A1

  公开（公告）日：2022-01-20

  The present invention relates to a composition and a product which are used when cooking food containing carbohydrates and proteins as main ingredients, when cooling processed food such as ramen, when preparing vegetable protein food such as tofu, or when administering alcoholic beverages, coffee, tea, beverages and the like, so as to increase the elasticity, texture or taste of prepared or cooked food, thereby improving the flavor thereof.
• Anti-plasmin inhibitor. V. Structures of novel dimeric eckols isolated from the brown alga Ecklonia kurome Okamura.
  作者：Yoshiyasu FUKUYAMA、Mitsuaki KODAMA、Iwao MIURA、Ziunei KINZYO、Hideo MORI、Yasuo NAKAYAMA、Masayuki TAKAHASHI

  DOI：10.1248/cpb.37.2438

  日期：——

  6, 6'-Bieckol (1), 2-O-(2, 4, 6-trihydroxyphenyl)-6, 6'-bieckol (4), and 8, 8'-bieckol (2), bispolyphenols with a dibenzo-1, 4-dioxin skeleton, have been isolated as potent anti-plasmin inhibitors from the brown alga Ecklonia kurome OKAMURA. Their structures have been determined to be dimers of eckol linked at the C-6 or C-8 positions, through an aryl-aryl bond on the basis of spectral data. Their inhibitory actions on anti-plasmins (α2-macroglobulin and α2-plasmin inhibitor) and some proteases have been examined.