radulanin I | 132839-41-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: radulanin I
• 英文别名: 1a-methyl-5-(2-phenylethyl)-2,7b-dihydro-1H-cyclopropa[c]chromen-7-ol
• CAS: 132839-41-9
• 化学式: C₁₉H₂₀O₂
• 分子量: 280.367
• InChiKey: WDDPYCJVJMDZKP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  radulanin I 、 碘甲烷 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 反应 2.0h， 生成 radulanin J
  参考文献：
  名称：

  Cyclopropanochroman derivatives from the liverwort Radula javanica

  摘要：

  Three new cyclopropanochromans, radulanins I, J and K were isolated from the liverwort Radula javanica, along with the previously known three prenyl bibenzyls, radulanins A and H, and 2-geranyl-3,5-dihydroxybibenzyl and a new cuparene-type sesquiterpenoid, (-)-2-(1,2,2-trimethyl)-cyclopentyl-6-methyl-1,4-quinone. The structures of the new compounds were 3-methyl-6-hydroxy-8-(2-phenylethyl)-3,5-cyclopropanochroman, 3-methyl-6-methoxy-8-(2-phenylethyl)-3,5-cyclopropanochroman and 3-methyl-6-hydroxy-7-carboxy-8-(2-phenylethyl)-3,5-cyclopropanochroman from their H-1 and C-13 NMR spectral data.

  DOI：

  10.1016/0031-9422(91)84147-k

文献信息

• Cyclopropanochroman derivatives from the liverwort Radula javanica
  作者：Yoshinori Asakawa、Keiko Kondo、Motoo Tori

  DOI：10.1016/0031-9422(91)84147-k

  日期：1991.1

  Three new cyclopropanochromans, radulanins I, J and K were isolated from the liverwort Radula javanica, along with the previously known three prenyl bibenzyls, radulanins A and H, and 2-geranyl-3,5-dihydroxybibenzyl and a new cuparene-type sesquiterpenoid, (-)-2-(1,2,2-trimethyl)-cyclopentyl-6-methyl-1,4-quinone. The structures of the new compounds were 3-methyl-6-hydroxy-8-(2-phenylethyl)-3,5-cyclopropanochroman, 3-methyl-6-methoxy-8-(2-phenylethyl)-3,5-cyclopropanochroman and 3-methyl-6-hydroxy-7-carboxy-8-(2-phenylethyl)-3,5-cyclopropanochroman from their H-1 and C-13 NMR spectral data.