2-bromo-1-pentafluorosulfanylcyclohexane | 950769-07-0

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代烷
• 英文名称: 2-bromo-1-pentafluorosulfanylcyclohexane
• 英文别名: 1-pentafluorosulfanyl-2-bromocyclohexane；(2-Bromocyclohexyl)-pentafluoro-lambda6-sulfane；(2-bromocyclohexyl)-pentafluoro-λ6-sulfane
• CAS: 950769-07-0
• 化学式: C₆H₁₀BrF₅S
• 分子量: 289.107
• InChiKey: BDVKDEMRZFOGBT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  1
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  环己烯 在 potassium fluoride 、 pentafluorosulfanyl bromide 作用下， 以 正戊烷 为溶剂， 反应 1.5h， 生成 2-bromo-1-pentafluorosulfanylcyclohexane
  参考文献：
  名称：

  Synthesis of pentafluorosulfuranyl substituted alkanes

  摘要：

  将SF5基团加到有机化合物，如烷基取代末端烯烃、内烯烃和环烯烃，通过与SF5Br反应在液相条件下进行，通常在自由基引发剂的存在下进行，最好使用三乙基硼。

  公开号：

  US06870068B1

文献信息

• Synthesis of pentafluorosulfuranyl substituted alkanes
  申请人：Lal Gauri Sankar

  公开号：US06870068B1

  公开（公告）日：2005-03-22

  Addition of an SF 5 group to organic compounds such as alkyl-substituted terminal alkenes, internal alkenes and cycloalkenes via the reaction with SF 5 Br is effected under liquid phase conditions and generally in the presence of a free radical initiator, preferably triethyl borane.

  将SF5基团加到有机化合物，如烷基取代末端烯烃、内烯烃和环烯烃，通过与SF5Br反应在液相条件下进行，通常在自由基引发剂的存在下进行，最好使用三乙基硼。
• Improved and facile addition reactions of pentafluorosulfanyl bromide
  作者：Dong Sung Lim、Silvana C. Ngo、Sankar G. Lal、Kristen E. Minnich、John T. Welch

  DOI：10.1016/j.tetlet.2008.07.080

  日期：2008.9

  A solution of SF(5)Br in CCl(3)F (0.5-1 M) Was utilized to effect the addition of pentafluorosulfanyl bromide (SF(5)Br) to olefins. The reaction of the SF5Br solution in the presence of triethylborane (0.1 equiv) With an olefin over 20 min at 0 degrees C gave pentafluorosulfanylated compound 2(a-f) in high yield (Table 2). An efficient route for the preparation of synthetically useful SF5-containing esters is also described. (C) 2008 Elsevier Ltd. All rights reserved.
• US6870068B1
  申请人：——

  公开号：US6870068B1

  公开（公告）日：2005-03-22
• A convenient and efficient method for incorporation of pentafluorosulfanyl (SF5) substituents into aliphatic compounds
  作者：William R. Dolbier、Samia Aït-Mohand、Tyler D. Schertz、Tatiana A. Sergeeva、Joseph A. Cradlebaugh、Akira Mitani、Gary L. Gard、Rolf W. Winter、Joseph S. Thrasher

  DOI：10.1016/j.jfluchem.2006.05.003

  日期：2006.10

  Both SF5Cl and SF5Br undergo smooth, high yield addition to alkenes and alkynes under the mild free radical chain reaction conditions of triethylborane initiation at low temperature, although the SF5Br chemistry is somewhat limited by its competing high electrophilic reactivity with electron rich alkenes. The SF5Cl addition reaction is relatively insensitive to a wide variety of non-allylic functionalities. (c) 2006 Elsevier B.V. All rights reserved.