cyclopent-2-ene-1,2-dicarbonitrile | 1427471-85-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: cyclopent-2-ene-1,2-dicarbonitrile
• 英文别名: Cyclopent-2-ene-1,2-dicarbonitrile
• CAS: 1427471-85-9
• 化学式: C₇H₆N₂
• 分子量: 118.138
• InChiKey: OXQZZZGSFIPVIT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  47.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  (2-氰基环戊-2-烯-1-基)乙酸酯 以 水 为溶剂， 生成 cyclopent-2-ene-1,2-dicarbonitrile
  参考文献：
  名称：

  Elegant Synthesis of Highly Functionalized 1,2,3-Trisubstituted Cyclopentanes

  摘要：

  The conversion of cyclic Baylis-Hillman acetates 1 into the corresponding cyano derivatives 2 was achieved using potassium cyanide in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) in aqueous medium. The obtained Michael acceptors 2 easily add primary amines in absolute ethanol to produce a new family of 1,2,3-trisubstituted cyclpentanes 3 in good yields.

  DOI：

  10.1080/00397911.2011.654371

文献信息

• [EN] METHOD FOR PREPARATION OF OCTAHYDROCYCLOPENTA[C]PYRROLE<br/>[FR] PROCÉDÉ DE PRÉPARATION DE OCTAHYDROCYCLOPENTA[C]PYRROLE
  申请人：LONZA AG

  公开号：WO2013102634A1

  公开（公告）日：2013-07-11

  The invention discloses a method for the preparation of octahydrocyclopenta[c]pyrrole, also called 3-azabicyclo[3.3.0]octane, by hydrogenation of 1,2-dicyanocyclo-1-pentene.

  本发明公开了一种制备八氢环戊[c]吡咯（也称为3-氮杂双环[3.3.0]辛烷）的方法，通过对1,2-二氰基环-1-戊烯进行氢化。
• METHOD FOR PREPARATION OF OCTAHYDROCYCLOPENTA[C]PYRROLE
  申请人：Lonza Ltd

  公开号：EP2800739B1

  公开（公告）日：2015-12-23
• Method For Preparation of Octahydrocyclopenta[c]pyrrole
  申请人：Lonza Ltd

  公开号：US20150183740A1

  公开（公告）日：2015-07-02

  The invention discloses a method for the preparation of octahydrocyclopenta[c]pyrrole, also called 3-azabicyclo[3.3.0]octane, by hydrogenation of 1,2-dicyanocyclo-1-pentene.
• US9126930B2
  申请人：——

  公开号：US9126930B2

  公开（公告）日：2015-09-08
• Elegant Synthesis of Highly Functionalized 1,2,3-Trisubstituted Cyclopentanes
  作者：Fatma Saâdi、Aïcha Arfaoui、Hassen Amri

  DOI：10.1080/00397911.2011.654371

  日期：2013.6.3

  The conversion of cyclic Baylis-Hillman acetates 1 into the corresponding cyano derivatives 2 was achieved using potassium cyanide in the presence of 1,4-diazabicyclo[2.2.2]octane (DABCO) in aqueous medium. The obtained Michael acceptors 2 easily add primary amines in absolute ethanol to produce a new family of 1,2,3-trisubstituted cyclpentanes 3 in good yields.