alternethanoxin A | 1177424-32-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: alternethanoxin A
• 英文别名: 1-[(6R)-1,4,6-trihydroxy-7-methoxy-6H-benzo[c]chromen-2-yl]ethanone
• CAS: 1177424-32-6
• 化学式: C₁₆H₁₄O₆
• 分子量: 302.284
• InChiKey: VCSBQDYZRLMMNP-MRXNPFEDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  96.2
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  alternethanoxin A 、 乙酸酐 在 吡啶 作用下， 以8 mg的产率得到triacetylalternethanoxin B
  参考文献：
  名称：

  Alternethanoxins A and B, Polycyclic Ethanones Produced by Alternaria sonchi, Potential Mycoherbicides for Sonchus arvensis Biocontrol

  摘要：

  Alternaria sonchi is a fungal pathogen isolated from Sonchus arvensis and proposed as a biocontrol agent of this noxious perennial weed. Different phytotoxic metabolites were isolated from solid culture of the fungus. Two new polycyclic ethanones, named alternethanoxins A and B, were characterized using essentially spectroscopic and chemical methods. Tested by leaf disk-puncture assay on the fungal host plant and a number of nonhost plants, alternethanoxins A and B were shown to be phytotoxic, whereas they did not possess antimicrobial activity tested at 100 mu g/disk. Hence, alternethanoxins A and B have potential as nonselective natural herbicides. Some structure-activity relationship observations were also made.

  DOI：

  10.1021/jf9014944