1-N-ethylbutane-1,3-diamine | 1249101-77-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-N-ethylbutane-1,3-diamine
• CAS: 1249101-77-6
• 化学式: C₆H₁₆N₂
• 分子量: 116.206
• InChiKey: ZVSKBEICYCVPKS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  8
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  38
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-N-ethylbutane-1,3-diamine 、 5-(2-amino-phenyl)-[1,3,4]oxadiazole-2-carboxylic acid ethyl ester hydrochloride 在 N,N-二异丙基乙胺 作用下， 以 乙醇 为溶剂， 生成 5-(2-aminophenyl)-[1,3,4]oxadiazole-2-carboxylic acid piperidin-4-ylamide
  参考文献：
  名称：

  Divergent Modes of Enzyme Inhibition in a Homologous Structure−Activity Series

  摘要：

  A (locking screen identified reversible, noncovalent inhibitors (e.g., I) of the parasite cysteine protease cruzain. Chemical optimization of I led to a series of oxadiazoles possessing interpretable SAR and potencies as much as 500-fold greater than 1. Detailed investigation of the SAR series subsequently revealed that many members of the oxadiazole class (and surprisingly also 1) act via divergent modes of inhibition (competitive or via colloidal aggregation) depending oil the assay conditions employed.

  DOI：

  10.1021/jm9009229

文献信息

• AROMATIC COPOLYMER AND COMPOSITION CONTAINING THE SAME
  申请人：Asahi Kasei Kogyo Kabushiki Kaisha

  公开号：EP0940419A1

  公开（公告）日：1999-09-08

  Disclosed is an aromatic copolymer comprising a plurality of aromatic copolymer chains, each comprising (A) recurring 2,6-diphenylphenol units and (B) phenolic comonomer units, each comonomer unit being independently selected from the group consisting of (i) an oxyphenylene monomer unit which is monosubstituted with a monovalent aromatic group or a halogen atom, (ii) an α-oxynaphthylene monomer unit, (iii) a β- oxynaphthylene monomer unit, and (iv) an oxyphenylene monomer unit which is substituted with at least one aliphatic group, wherein the amounts of (A) and (B) are from 50 to 98 % by weight and from 2 to 50 % by weight, based on the weight of the aromatic copolymer, provided that, when (iv) is present as the comonomer unit, the amount of (iv) is 20 % by weight or less, based on the weight of (B), and wherein the aromatic copolymer has a weight average molecular weight of from 1,000 to 3,000,000. A method for producing the aromatic copolymer is also disclosed. The aromatic copolymer of the present invention has excellent electrical characteristics (such as a low dielectric constant), an excellent heat resistance, excellent film-forming properties, low water absorption properties and an excellent adhesion to other materials, and can be advantageously used as a material for various electronic parts.

  本发明公开了一种芳香族共聚物，该共聚物由多条芳香族共聚物链组成，每条芳 香族共聚物链包括(A)重复的 2,6-二苯酚单元和(B)酚类共聚单体单元，每个共聚单体单元 独立选自以下组：(i)被一价芳香族基团或卤原子单取代的氧亚苯基单体单元；(ii)α-氧杂萘 乙烯单体单元；(iii)β-氧杂萘 乙烯单体单元；以及(iv)被至少一个脂肪族基团取代的氧亚苯基单体单元、和(iv)被至少一个脂肪族基团取代的氧亚苯基单体单元，其中(A)和(B)的量按芳香族共聚物的重量计分别为 50%至 98%和 2%至 50%，条件是当(iv)作为共聚单体单元存在时，(iv)的量按(B)的重量计为 20%或更少，其中芳香族共聚物的重量平均分子量为 1,000 至 3,000,000 。本发明还公开了一种生产芳香族共聚物的方法。本发明的芳香族共聚物具有优异的电气特性（如低介电常数）、优异的耐热性、优异的成膜性、低吸水性和与其他材料优异的粘合性，可作为各种电子零件的材料使用。
• GRAFT COPOLYMERS PREPARED FROM SOLVENT-FREE REACTIONS AND DISPERSANT DERIVATIVES THEREOF
  申请人：The Lubrizol Corporation

  公开号：EP0285609A1

  公开（公告）日：1988-10-12
• PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT
  申请人：Gilead Sciences, Inc.

  公开号：US20170362244A1

  公开（公告）日：2017-12-21

  The invention provides compounds of Formula I or Formula II: or a pharmaceutically acceptable salt or ester, thereof, as described herein. The compounds and compositions thereof are useful for treating Pneumovirinae virus infections. The compounds, compositions, and methods provided are particularly useful for the treatment of Human respiratory syncytial virus infections.
• US6323300B1
  申请人：——

  公开号：US6323300B1

  公开（公告）日：2001-11-27
• [EN] GRAFT COPOLYMERS PREPARED FROM SOLVENT-FREE REACTIONS AND DISPERSANT DERIVATIVES THEREOF
  申请人：THE LUBRIZOL CORPORATION

  公开号：WO1987003890A1

  公开（公告）日：1987-07-02

  (EN) Compositions useful as oil additives are prepared in a solvent or a solvent free system by reacting (B) an unsaturated carboxylic acid reagent with (A) a hydrogenated block copolymer in the presence of (C) free radical initiators. The formed reaction product (D) can be further reacted with a (E) primary amine-containing compound in a solvent or a solvent free system.(FR) On prépare des compositions utiles comme additifs d'huiles dans un système à solvant ou dépourvu de solvant en faisant réagir (B), un réactif d'acide carboxylique insaturé, avec (A), un copolymère bloc hydrogéné, en présence de (C), des initiateurs à radicaux libres. On peut en outre faire réagir le produit de réaction (D) ainsi obtenu avec (E), un composé primaire contenant de l'amine dans un système à solvant ou dépourvu de solvant.