N-(5-tert-butyl-1,2-oxazol-3-yl)propanamide

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-(5-tert-butyl-1,2-oxazol-3-yl)propanamide
• 化学式: C₁₀H₁₆N₂O₂
• mdl: MFCD00466642
• 分子量: 196.25
• InChiKey: BDLVSEWUCZQDTD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  55.1
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-(5-tert-butyl-1,2-oxazol-3-yl)propanamide 、 磺酰氯 生成 N-(5-tert-butyl-4-chloro-1,2-oxazol-3-yl)propanamide
  参考文献：
  名称：

  摘要：

  DOI：
• 作为产物：
  描述：

  3-氨基-5-叔丁基异唑 、 丙酸酐 生成 N-(5-tert-butyl-1,2-oxazol-3-yl)propanamide
  参考文献：
  名称：

  YUKINAGA, HISAJIRO;SUMIMOTO, SHINZABURO;ISHIZUKA, ICHIRO;SUGITA, JITSUO

  摘要：

  DOI：

文献信息

• N-(5-t-Butyl-3-isoxazolyl)alkanamide derivatives and herbicidal
  申请人：Shionogi & Co., Ltd.

  公开号：US04293328A1

  公开（公告）日：1981-10-06

  Herbicidal compounds represented by the formula: ##STR1## wherein R is t-butyl; R.sup.1 is hydrogen or methyl; R.sup.2 is alkyl (C.sub.2 to C.sub.6), alkenyl (C.sub.3 to C.sub.4) or cyclopropyl; and X is hydrogen or halogen; and herbicidal compositions containing them.

  式为：##STR1##的除草剂化合物，其中R为叔丁基；R.sup.1为氢或甲基；R.sup.2为烷基（C.sub.2 to C.sub.6），烯基（C.sub.3 to C.sub.4）或环丙基；X为氢或卤素；以及含有它们的除草剂组合物。
• Heterocyclic Compounds Which Modulate The CB2 Receptor
  申请人：Bartolozzi Alessandra

  公开号：US20110312944A1

  公开（公告）日：2011-12-22

  Compounds which modulate the CB2 receptor are disclosed. Compounds according to the invention bind to and are agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.

  本发明揭示了调节CB2受体的化合物。根据本发明，这些化合物与CB2受体结合并作为激动剂，用于治疗炎症。那些作为激动剂的化合物还可用于治疗疼痛。
• Azetidine 2-Carboxamide Derivatives Which Modulate The CB2 Receptor
  申请人：Hickey Eugene Richard

  公开号：US20120142666A1

  公开（公告）日：2012-06-07

  Compounds of the formula (I), (II) and (III) which modulate the CB2 receptor are disclosed. Compounds according to the invention bind to and are agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.

  公式（I），（II）和（III）的化合物被揭示，这些化合物可以调节CB2受体。本发明的化合物结合并是CB2受体的激动剂，可用于治疗炎症。那些是激动剂的化合物还可用于治疗疼痛。
• AGENT FOR IMPROVEMENT IN BOUNCE/BODY OF HAIR, AND HAIR COSMETIC
  申请人：Shiseido Company, Limited

  公开号：EP1911750A1

  公开（公告）日：2008-04-16

  A hair resiliency and body improver comprising as the active ingredient thereof one or more types of compounds selected from the group consisting of 2-aminothiazole derivatives represented by the following general formula (1) or 3-aminoisoxazole derivatives represented by the following general formula (2), and pharmaceutically acceptable salts thereof: (wherein, R1, R2, R3, R4, n and m are as defined in the description).

  一种头发弹性和发质改善剂，其活性成分包括一种或多种选自由下通式 (1) 所代表的 2-氨基噻唑衍生物或自由下通式 (2) 所代表的 3-氨基异恶唑衍生物组成的组的化合物及其药学上可接受的盐类： (其中，R1、R2、R3、R4、n 和 m 如说明中所定义）。
• Hair resiliency / body improver and hair cosmetic
  申请人：Shiseido Company, Limited

  公开号：EP2484342A1

  公开（公告）日：2012-08-08

  A hair resiliency and body improver comprising as the active ingredient thereof one or more types of compounds selected from the group consisting of 2-aminothiazole derivatives represented by the following general formula (1) or 3-aminoisoxazole derivatives represented by the following general formula (2), and pharmaceutically acceptable salts thereof: (wherein, R1, R2, R3, R4, n and m are as defined in the description).

  一种头发弹性和发质改善剂，其活性成分包括一种或多种选自由下通式 (1) 所代表的 2-氨基噻唑衍生物或自由下通式 (2) 所代表的 3-氨基异恶唑衍生物组成的组的化合物及其药学上可接受的盐类： (其中，R1、R2、R3、R4、n 和 m 如说明中所定义）。