碘二噻宁 | 713075-08-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 中文名称: 碘二噻宁
• 英文名称: 1,1'-Diethyl-pentamethinbenzthiazolcyanin
• 英文别名: 3,3'-Diethylthiacarbocyanin；3,3'-Diethyl-thiadicarbocyanin-iodid；<2-Bis-(3-aethyl-benzothiazolyl)>-pentamethincyanin；1,5-bis-(3-ethyl-benzothiazol-2-yl)-pentamethinium；3-ethyl-2-[5-(3-ethyl-3H-benzothiazol-2-ylidene)-penta-1,3-dienyl]-benzothiazolium；(2E)-3-ethyl-2-[(2E)-5-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-1,3-benzothiazole
• CAS: 713075-08-2
• 化学式: C₂₃H₂₃N₂S₂
• mdl: MFCD00242881
• 分子量: 391.581
• InChiKey: FYXWDSGGZAMYFZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  60.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1,1,5,5-Tetracyanopentadien 、 碘二噻宁 以 乙醇 为溶剂， 以75%的产率得到
  参考文献：
  名称：

  Novel polymethine dyes derived from aminals and aminal-acetals of conjugated ?-dimethylaminoaldehydes

  摘要：

  DOI：

  10.1007/bf00953705

文献信息

• Multi-functional ionic liquid compositions for overcoming polymorphism and imparting improved properties for active pharmaceutical, biological, nutritional, and energetic ingredients
  申请人：Rogers D. Robin

  公开号：US20070093462A1

  公开（公告）日：2007-04-26

  Disclosed are ionic liquids and methods of preparing ionic liquid compositions of active pharmaceutical, biological, nutritional, and energetic ingredients. Also disclosed are methods of using the compositions described herein to overcome polymorphism, overcome solubility and delivery problems, to control release rates, add functionality, enhance efficacy (synergy), and improve ease of use and manufacture.

  揭示了离子液体及制备活性药物、生物、营养和能量成分的离子液体组合物的方法。还揭示了利用本文描述的组合物的方法，以克服多型性、克服溶解度和输送问题、控制释放速率、增加功能性、增强功效（协同作用）以及改善易用性和制造工艺。
• PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES
  申请人：Lukhtanov Eugeny

  公开号：US20080207887A1

  公开（公告）日：2008-08-28

  Reagents are provided for the introduction of phosphonate groups into fluorescent dyes. Methods are also provided for preparing dye conjugates.

  试剂提供了将膦酸酯基团引入荧光染料中的方法。同时还提供了制备染料偶联物的方法。
• Phosphonate fluorescent dyes and conjugates
  申请人：Lukhtanov Eugeny

  公开号：US20070172832A1

  公开（公告）日：2007-07-26

  Reagents are provided for the introduction of phosphonate groups into fluorescent dyes. Methods are also provided for preparing dye conjugates.

  提供试剂用于将膦酸基团引入荧光染料中。同时还提供了制备染料共轭物的方法。
• Surface Grafted Conjugated Polymers
  申请人：Whitten David G.

  公开号：US20110159605A1

  公开（公告）日：2011-06-30

  A surface grafted conjugated polyelectrolyte (CPE) is formed by coupling a CPE by a coupling moiety to the surface of a substrate. The substrate can be of any shape and size, and for many uses of the surface grafted CPE, it is advantageous that the substrate is a nanoparticle or microparticle. Surface grafted CPEs are presented that use silica particles as the substrate, where a modified silane coupling agent connects the surface to the CPE by a series of covalent bonds. Two methods of preparing the surface grafted CPEs are presented. One method involves the inclusion of the surface being modified by the coupling agent and condensed with monomers that form the CPE in a grafted state to the substrate. A second method involves the formation of a CPE with terminal groups that are complimentary to functionality that has been placed on the surface of the substrate by reaction with a coupling agent. The surface grafted CPEs are also described for use as biosensors and biocides.

  一种表面接枝的共轭聚电解质（CPE）是通过将CPE与偶联基耦合到基底表面上形成的。基底可以是任何形状和大小，对于许多使用表面接枝CPE的应用来说，基底是纳米颗粒或微粒是有优势的。介绍了使用硅颗粒作为基底的表面接枝CPE，其中经过改性的硅烷偶联剂通过一系列共价键将表面连接到CPE。介绍了两种制备表面接枝CPE的方法。一种方法涉及将表面包括在偶联剂中进行修饰，并与形成接枝状态的单体缩合形成CPE。第二种方法涉及形成具有末端基团的CPE，这些基团与通过与偶联剂反应放置在基底表面上的功能互补。还描述了将表面接枝CPE用作生物传感器和生物杀菌剂的用途。
• Multi-Functional Ionic Liquid Compositions for Overcoming Polymorphism and Imparting Improved Properties for Active Pharmaceutical, Biological, Nutritional, and Energetic Ingredients
  申请人：Rogers Robin D.

  公开号：US20120264605A1

  公开（公告）日：2012-10-18

  Disclosed are ionic liquids and methods of preparing ionic liquid compositions of active pharmaceutical, biological, nutritional, and energetic ingredients. Also disclosed are methods of using the compositions described herein to overcome polymorphism, overcome solubility and delivery problems, to control release rates, add functionality, enhance efficacy (synergy), and improve ease of use and manufacture.

  本发明涉及离子液体和制备含有活性制药、生物、营养和能量成分的离子液体组合物的方法。同时，本发明还涉及使用所述组合物的方法，以克服多晶性、克服溶解度和输送问题、控制释放速率、增加功能、增强功效（协同作用）和改善使用和制造的便利性。