Benzofuran-2-yl-p-tolyl-methanone oxime | 478686-06-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 英文名称: Benzofuran-2-yl-p-tolyl-methanone oxime
• 英文别名: N-[1-benzofuran-2-yl-(4-methylphenyl)methylidene]hydroxylamine
• CAS: 478686-06-5
• 化学式: C₁₆H₁₃NO₂
• 分子量: 251.285
• InChiKey: FAICWYAOUJSPDF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  45.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 Benzofuran-2-yl-p-tolyl-methanone oxime 反应 1.0h， 以40%的产率得到[[1-benzofuran-2-yl-(4-methylphenyl)methylidene]amino] acetate
  参考文献：
  名称：

  Synthesis and antifungal activities of some aryl(benzofuran-2-yl)ketoximes

  摘要：

  In this study, some aryl(benzofuran-2-yl)ketoximes and their ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, H-1 NMR and mass spectroscopic data and elemental analyses results. Antifungal activities of the compounds were examined and notable activity was obtained. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

  DOI：

  10.1016/s0014-827x(02)01257-0
• 作为产物：
  描述：

  benzofuran-2-yl(p-tolyl)methanone 在 盐酸羟胺 、 sodium acetate 作用下， 以 乙醇 为溶剂， 反应 3.0h， 以80%的产率得到Benzofuran-2-yl-p-tolyl-methanone oxime
  参考文献：
  名称：

  Synthesis and antifungal activities of some aryl(benzofuran-2-yl)ketoximes

  摘要：

  In this study, some aryl(benzofuran-2-yl)ketoximes and their ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, H-1 NMR and mass spectroscopic data and elemental analyses results. Antifungal activities of the compounds were examined and notable activity was obtained. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

  DOI：

  10.1016/s0014-827x(02)01257-0

文献信息

• Synthesis and antifungal activities of some aryl(benzofuran-2-yl)ketoximes
  作者：Şeref Demirayak、Ümit Uçucu、Kadriye Benkli、Nalan Gündoğdu-Karaburun、Ahmet Çağrı Karaburun、Derya Akar、Muhammed Karabacak、Nuri Kiraz

  DOI：10.1016/s0014-827x(02)01257-0

  日期：2002.7

  In this study, some aryl(benzofuran-2-yl)ketoximes and their ethers and esters were synthesised. The structure elucidation of the compounds was performed by IR, H-1 NMR and mass spectroscopic data and elemental analyses results. Antifungal activities of the compounds were examined and notable activity was obtained. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.