5-Amino-2-(2-carboxyethyl)-benzoesaeure | 94237-93-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: 5-Amino-2-(2-carboxyethyl)-benzoesaeure
• 英文别名: 5-Amino-2-(2-carboxyethyl)benzoic acid；5-amino-2-(2-carboxyethyl)benzoic acid
• CAS: 94237-93-1
• 化学式: C₁₀H₁₁NO₄
• 分子量: 209.202
• InChiKey: ZGRKIEYHZYLYKH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  101
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  5-Amino-2-(2-carboxyethyl)-benzoesaeure 在 三氯化铝 、 三乙胺 、 sodium chloride 作用下， 以 乙醚 为溶剂， 反应 3.5h， 生成 6-acetylamino-1-oxo-indan-4-carboxylic acid
  参考文献：
  名称：

  Synthesis of 6-azido-1-oxo-indan-4-oyl isoleucine; a photoaffinity approach to plant signaling

  摘要：

  The synthesis of the photoreactive 6-azido-1-oxo-indanoyl isoleucine (3), as a molecular probe for the identification of putative receptors and binding proteins involved in stress signaling of plants, is described. The biological activity of the photolabile azide 3 comes close to that of the bacterial phytotoxin coronatine (1). Photodecomposition of 3 in the presence of myoglobin is assumed to proceed via an didehydroazepine intermediate and results in significant binding of the probe to the model protein. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(99)00097-6
• 作为产物：
  描述：

  5-nitro-2-(2-carboxy-ethyl)-benzoic acid 在 palladium on activated charcoal sodium hydroxide 、 氢气 作用下， 反应 18.0h， 生成 5-Amino-2-(2-carboxyethyl)-benzoesaeure
  参考文献：
  名称：

  Synthesis of 6-azido-1-oxo-indan-4-oyl isoleucine; a photoaffinity approach to plant signaling

  摘要：

  The synthesis of the photoreactive 6-azido-1-oxo-indanoyl isoleucine (3), as a molecular probe for the identification of putative receptors and binding proteins involved in stress signaling of plants, is described. The biological activity of the photolabile azide 3 comes close to that of the bacterial phytotoxin coronatine (1). Photodecomposition of 3 in the presence of myoglobin is assumed to proceed via an didehydroazepine intermediate and results in significant binding of the probe to the model protein. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(99)00097-6

文献信息

• Synthesis of 6-azido-1-oxo-indan-4-oyl isoleucine; a photoaffinity approach to plant signaling
  作者：Göde Schüler、Claus Wasternack、Wilhelm Boland

  DOI：10.1016/s0040-4020(99)00097-6

  日期：1999.3

  The synthesis of the photoreactive 6-azido-1-oxo-indanoyl isoleucine (3), as a molecular probe for the identification of putative receptors and binding proteins involved in stress signaling of plants, is described. The biological activity of the photolabile azide 3 comes close to that of the bacterial phytotoxin coronatine (1). Photodecomposition of 3 in the presence of myoglobin is assumed to proceed via an didehydroazepine intermediate and results in significant binding of the probe to the model protein. (C) 1999 Elsevier Science Ltd. All rights reserved.