N-Isobutyl-noradrenalin | 739301-51-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: N-Isobutyl-noradrenalin
• 英文别名: 1-(3,4-dihydroxy-phenyl)-2-isobutylamino-ethanol；1-(3,4-Dihydroxy-phenyl)-2-isobutylamino-aethanol；3,4-Dihydroxy-alpha-((isobutylamino)methyl)benzyl alcohol；4-[1-hydroxy-2-(2-methylpropylamino)ethyl]benzene-1,2-diol
• CAS: 739301-51-0
• 化学式: C₁₂H₁₉NO₃
• 分子量: 225.288
• InChiKey: TXLFMUAEFKUGBZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  72.7
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 水 、 钯 作用下， 生成 N-Isobutyl-noradrenalin
  参考文献：
  名称：

  Preparation of N-Substituted 1-(3′,4′-Dihydroxyphenyl)-2-aminoethanols

  摘要：

  DOI：

  10.1021/ja01170a044

文献信息

• Engineered rice having alcoholism relief and liver protection function, and preparation method thereof
  申请人：CHINA NATIONAL RESEARCH INSTITUTE OF FOOD AND FERMENTATION INDUSTRIES CO., LTD.

  公开号：US10010573B2

  公开（公告）日：2018-07-03

  The present invention relates to a functional engineered rice having alcoholism relief and liver protection functions for those drinking alcohol over an extended period of time or drinking alcohol excessively, and preparation method thereof. The engineered rice comprises six starting materials: coarse rice powder, isolated soy protein, kudzu root extract, corn oligopeptide, purple sweet potato powder, and hawthorn extract, and is prepared by: premixing the starting materials; employing a double screw extruder to conduct texturized processing and forming under high temperature and high pressure; and then drying, dedusting and packaging.

  本发明涉及一种对长期饮酒或过量饮酒者具有解酒护肝功能的功能性工程米及其制备方法。该工程米由粗米粉、分离大豆蛋白、葛根提取物、玉米低聚肽、紫甘薯粉、山楂提取物六种起始原料组成，其制备方法为：将起始原料进行预混合；采用双螺杆挤压机在高温高压下进行膨化加工成型；然后进行干燥、除尘和包装。
• Composition of natural herb extract for treating cardiovascular disease and its method of preparation thereof
  申请人：Young Jeffrey

  公开号：US20060083798A1

  公开（公告）日：2006-04-20

  A composition of natural herb extract for treating cardiovascular disease or vascular disorder and its method of preparation and separation, and particularly to a composition prepared from natural herb extract comprising constituents of Danshensu, Tanshinone IIA, matrine, oxymatrine and puerarin for lowering the risk factors of heart disease or treating the heart disease that side effects are minimized. The working ranges of Danshensu, Tanshinone IIA, matrine, oxymatrine and puerarin are between 5 and 40 mg/kg per day and a ratio of Danshensu, Tanshinone IIA, matrine, oxymatrine, and puerarin is 1:1:1:1:1. The extraction and separation method of the five active ingredients are also illustrated. The composition can be exhibit in different forms for administration.

  一种治疗心血管疾病或血管疾病的天然草本植物提取物组合物及其制备和分离方法，特别是由丹参素、丹参酮ⅡA、马钱子碱、氧化苦参碱和葛根素等成分组成的天然草本植物提取物制备的组合物，用于降低心脏病的危险因素或治疗心脏病，使副作用最小化。丹参素、丹参酮 IIA、马钱子碱、氧化苦参碱和葛根素的作用范围为每天 5 至 40 毫克/千克，丹参素、丹参酮 IIA、马钱子碱、氧化苦参碱和葛根素的配比为 1:1:1:1:1:1。此外，还说明了五种有效成分的提取和分离方法。该组合物可以不同的形式展出，以供服用。
• ENGINEERED RICE HAVING ALCOHOLISM RELIEF AND LIVER PROTECTION FUNCTION, AND PREPARATION METHOD THEREOF
  申请人：CHINA NATIONAL RESEARCH INSTITUTE OF FOOD AND FERMENTATION INDUSTRIES

  公开号：US20150118336A1

  公开（公告）日：2015-04-30

  The present invention relates to a functional engineered rice having alcoholism relief and liver protection functions for those drinking alcohol over an extended period of time or drinking alcohol excessively, and preparation method thereof. The engineered rice comprises six starting materials: coarse rice powder, isolated soy protein, kudzu root extract, corn oligopeptide, purple sweet potato powder, and hawthorn extract, and is prepared by: premixing the starting materials; employing a double screw extruder to conduct texturized processing and forming under high temperature and high pressure; and then drying, dedusting and packaging. The coarse cereal components of the engineered rice have the effects of balancing the diet and ensuring nutrition ingestion for those consuming the rice; and the functional factors such as the corn oligopeptide, the kudzu root extract and the like have the functions of enhancing ethanol metabolism inside the body, reducing liver damage, relieving alcoholism and protecting the liver.
• US7384657B2
  申请人：——

  公开号：US7384657B2

  公开（公告）日：2008-06-10
• Preparation of N-Substituted 1-(3′,4′-Dihydroxyphenyl)-2-aminoethanols
  作者：John R. Corrigan、Marie-Jo. Langermann、Maurice L. Moore

  DOI：10.1021/ja01170a044

  日期：1949.2