N-2-异丙基-2-甲基-异丙基-1,2二胺 | 16256-44-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: N-2-异丙基-2-甲基-异丙基-1,2二胺
• 英文名称: N¹-Isopropyl-1,1-dimethyl-ethylendiamin
• 英文别名: N2-Isopropyl-2-methyl-propane-1,2-diamine；2-methyl-2-N-propan-2-ylpropane-1,2-diamine
• CAS: 16256-44-3
• 化学式: C₇H₁₈N₂
• 分子量: 130.233
• InChiKey: ULZVZRVDMKHKAL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  38
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-(异丙基氨基)-2-甲基丙腈 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 生成 N-2-异丙基-2-甲基-异丙基-1,2二胺
  参考文献：
  名称：

  Zum Reaktionsverhalten der Imidazolidin-thione-(4)

  摘要：

  DOI：

  10.1007/bf01167141

文献信息

• [EN] C-4" POSITION SUBSTITUTED MACROLIDE DERIVATIVE<br/>[FR] DÉRIVÉ DE MACROLIDE SUBSTITUÉ EN POSITION C-4"
  申请人：TAISHO PHARMA CO LTD

  公开号：WO2012115256A1

  公开（公告）日：2012-08-30

  A macrolide compound represented by the formula (I) effective against erythromycin resistant bacteria (for example, resistant pneumococci, streptococci and mycoplasmas).

  一种由化学式（I）表示的大环内酯化合物，对红霉素耐药细菌有效（例如，耐药的肺炎球菌、链球菌和支原体）。
• Synthesis of 2-keto-1,4-diazacycloalkanes
  申请人：The B.F. GOODRICH Company

  公开号：EP0001559A2

  公开（公告）日：1979-05-02

  Several novel syntheses have been discovered for preparation of 2-keto-1,4- diazacycloalkanes and their derivatives. Trans isomers of polysubstituted quinoxalin-2- ones may now be prepared.

  我们发现了几种制备 2-酮基-1,4-重氮环烷及其衍生物的新合成方法。 现在可以制备多取代喹喔啉-2-的反式异构体。
• Improved synthesis of 1,4-diaza-2-cycloalkanone and substituted derivatives thereof
  申请人：The B.F. GOODRICH Company

  公开号：EP0004460A1

  公开（公告）日：1979-10-03

  The present invention provides a process for the synthesis of a 1,4-diaza-2-cycloalkanone characterized in that a diamine of the formula wherein R1 and R2 are independently selected from hydrogen, halogen, alkyl of 1 to 12 carbon atoms, hydroxyalkyl, haloalkyl, cyanoalkyl, aminoalkyl, iminoalkyl, ether, nitrosyl, hydroxyalkyl ethers, cyano alkyl ethers, alkenyl, alkaline and carboalkoxy; R3 to R6 being independently selected from alkyl of 1 to 12 carbon atoms, cycloalkyl, hydroxycycloalkyl, aminoalkyl, iminoalkyl, alkenyl, aralkyl and alkylene, provided further that any two of the above hydrocarbon substituents pendant from the same carbon atoms can collectively form a cyclic or alicyclic hydrocarbon and n is 0 to 3 is contacted. in the presence of a phase transfer catalyst, with a stoichiometric excess of an a-trihaloalkyl- alcohol of the formula wherein R7 and R8 are selected from the same group of substituents as R3 to R6 X is halogen; and m is a number from 0 to 5.

  本发明提供了一种合成 1,4-二氮杂-2-环烷酮的工艺，其特征在于式中的二胺 其中 R1 和 R2 独立选自氢、卤素、1 至 12 个碳原子的烷基、羟基烷基、卤代烷基、氰基烷基、氨基烷基、亚氨基烷基、醚、亚硝基、羟基烷基醚、氰基烷基醚、烯基、烷基和羧基烷氧基；R3 至 R6 分别独立地选自 1 至 12 个碳原子的烷基、环烷基、羟基环烷基、氨基烷基、亚氨基烷基、烯基、芳基和亚烷基，条件是上述烃类取代基中任意两个由相同碳原子悬垂的取代基可共同形成环烃或脂环烃，且 n 为 0 至 3。在相转移催化剂的存在下，与按化学计量过量的式如下的 a-三卤代烷基醇接触 其中 R7 和 R8 选自与 R3 至 R6 相同的取代基组 X 为卤素；以及 m 为 0 至 5 的数字。
• Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them
  申请人：The Boots Company PLC

  公开号：EP0385038A1

  公开（公告）日：1990-09-05

  Compounds of formula I and their salts in which n = 0 or 1, R1 and R2 are each aliphatic or cycloalkyl or NR1 R2 is an optionally substituted heterocyclic ring, R3 is alkyl, cycloalkyl or optionally substituted amino, R5 is an aliphatic group, R6 is H, an optionally substituted aliphatic group or a cycloalkyl group, or R3 and R5 together with the nitrogen and carbon atoms to which they are attached form an optionally substituted heterocyclic ring or R5 and R6 together with the nitrogen to which they are attached form a heterocyclic ring optionally substituted by alkyl and R7 is optionally substituted alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, alkoxycarbonyl, trifluoromethyl or cyano have utility as hypoglycaemic agents.

  式 I 的化合物及其盐类 及其盐类，其中 n = 0 或 1，R1 和 R2 各为脂肪族或环烷基或 NR1 R2 为任选取代的杂环，R3 为烷基、环烷基或任选取代的氨基，R5 为脂肪族基团，R6 为 H、任选取代的脂肪族基团或环烷基基团、或 R3 和 R5 与它们所连接的氮原子和碳原子一起形成一个任选取代的杂环，或 R5 和 R6 与它们所连接的氮原子一起形成一个任选被烷基取代的杂环，R7 是任选取代的烷基、烷氧基、烷硫基、烷基亚砜基、烷基磺酰基、烷氧基羰基、三氟甲基或氰基。
• Process for aqueous coating
  申请人：A-LINE PRODUCTS CORPORATION

  公开号：EP1151854A1

  公开（公告）日：2001-11-07

  A method of making a multilayered article, comprising the steps: (1) providing a substrate; (2) applying to said substrate a composition including: (a) up to 40 percent of a polyol having a molecular weight of at least 62 to 500; (b) 0.5 percent to 40 percent of a resin selected from halogenated polyolefinic resin materials, halogenated vinyl resins, epihydrin resins, halogenated epoxy resins, and mixtures thereof, said resin having a molecular weight of 10,000 to 40,000, or a softening point of 150° to 350° F (65 to 177°C); (c) 0.05 to 15 percent of a surfactant; (d) an amine selected from primary, secondary and tertiary aliphatic amines having an amine functionality of 1 to 3, and mixtures thereof; and (e) 30 to 95% water, wherein the total volatile organic content in said composition is less than 5% by weight, and wherein said composition is substantially free of aromatic organic solvents; and (3) applying a layer of material on said composition of step (2).

  一种制作多层物品的方法，包括以下步骤 (1) 提供基底； (2) 在所述基底上涂敷一种组合物，该组合物包括 (a) 高达 40%的多元醇，其分子量至少为 62 至 500； (b) 0.5%至 40%的树脂，选自卤化聚烯烃树脂材料、卤化乙烯基树脂、环氧树脂、卤化环氧树脂及其混合物，所述树脂的分子量为 10,000 至 40,000 或软化点为华氏 150 度至 350 度（摄氏 65 度至 177 度）； (c) 0.05%至 15%的表面活性剂； (d) 选自胺官能度为 1 至 3 的伯胺、仲胺和叔胺的脂肪族胺及其混合物；以及 (e) 30%至 95%的水，其中所述组合物中的总挥发性有机物含量小于 5%（按 重量计），且所述组合物基本上不含芳香族有机溶剂；以及 (3) 在步骤（2）的所述组合物上涂上一层材料。