N-(tert-butyl)-2-bromo-3,3,3-triphenylpropanamide | 431946-28-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: N-(tert-butyl)-2-bromo-3,3,3-triphenylpropanamide
• 英文别名: 2-bromo-N-tert-butyl-3,3,3-triphenylpropanamide
• CAS: 431946-28-0
• 化学式: C₂₅H₂₆BrNO
• 分子量: 436.392
• InChiKey: AIMRMQLPQQWWNU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-(tert-butyl)-2-bromo-3,3,3-triphenylpropanamide 在 sodium t-butanolate 作用下， 以 四氢呋喃 为溶剂， 反应 1.75h， 生成 2,2,2-三苯基乙醛
  参考文献：
  名称：

  About Four New Trityl-substituted a-Lactams

  摘要：

  This investigation comprises the synthesis, a description of the physical and spectroscopic properties, determination of the limits of thermal stability, and reactions with protic and aprotic nucleophiles of four new trityl-substituted alpha-lactams. With the exception of 3,3-dimethyl-1-tritylaziridin-2-one (4a), which is unstable at room temperature, all new compounds have been fully characterized.

  DOI：

  10.3987/com-01-9365
• 作为产物：
  描述：

  叔丁胺 、 2-bromo-3,3,3-triphenylpropanoyl chloride 以 二氯甲烷 为溶剂， 反应 3.0h， 以82.6%的产率得到N-(tert-butyl)-2-bromo-3,3,3-triphenylpropanamide
  参考文献：
  名称：

  About Four New Trityl-substituted a-Lactams

  摘要：

  This investigation comprises the synthesis, a description of the physical and spectroscopic properties, determination of the limits of thermal stability, and reactions with protic and aprotic nucleophiles of four new trityl-substituted alpha-lactams. With the exception of 3,3-dimethyl-1-tritylaziridin-2-one (4a), which is unstable at room temperature, all new compounds have been fully characterized.

  DOI：

  10.3987/com-01-9365

文献信息

• About Four New Trityl-substituted a-Lactams
  作者：István Lengyel、Istvan Lengyel、Victor Cesare、Ian Adam、Tony Taldone

  DOI：10.3987/com-01-9365

  日期：——

  This investigation comprises the synthesis, a description of the physical and spectroscopic properties, determination of the limits of thermal stability, and reactions with protic and aprotic nucleophiles of four new trityl-substituted alpha-lactams. With the exception of 3,3-dimethyl-1-tritylaziridin-2-one (4a), which is unstable at room temperature, all new compounds have been fully characterized.