perfluorophthalide | 170574-02-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 英文名称: perfluorophthalide
• 英文别名: 3,3,4,5,6,7-hexafluoro-1-[3H]-isobenzofuranone；Perfluoro-phthalide；3,3,4,5,6,7-hexafluoro-2-benzofuran-1-one
• CAS: 170574-02-4
• 化学式: C₈F₆O₂
• 分子量: 242.077
• InChiKey: CZTVTLCOWCLOSM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  perfluorophthalide 在 溶剂黄146 作用下， 以87.5%的产率得到3,4,5,6-四氟苯酐
  参考文献：
  名称：

  Processes for producing tetrafluorophthalic anhydride and fluorobenzoic

  摘要：

  一种生产四氟邻苯二酐的方法，包括氯化四氯邻苯二酐以得到3,3,4,5,6,7-六氯-1-[3H]-异苯并呋喃酮，然后氟化它以得到3,4,5,6-四氟邻苯二酰二氟化物和/或3,3,4,5,6,7-六氟-1-[3H]-异苯并呋喃酮，然后进一步将四氟邻苯二酰二氟化物和/或六氟-1-[3H]-异苯并呋喃酮与无机碱或有机酸反应以得到四氟邻苯二酐。

  公开号：

  US05523476A1
• 作为产物：
  描述：

  hexachloro-phthalide 以 环丁砜 为溶剂， 生成 perfluorophthalide
  参考文献：
  名称：

  Processes for producing tetrafluorophthalic anhydride and fluorobenzoic

  摘要：

  一种生产四氟邻苯二酐的方法，包括氯化四氯邻苯二酐以得到3,3,4,5,6,7-六氯-1-[3H]-异苯并呋喃酮，然后氟化它以得到3,4,5,6-四氟邻苯二酰二氟化物和/或3,3,4,5,6,7-六氟-1-[3H]-异苯并呋喃酮，然后进一步将四氟邻苯二酰二氟化物和/或六氟-1-[3H]-异苯并呋喃酮与无机碱或有机酸反应以得到四氟邻苯二酐。

  公开号：

  US05523476A1

文献信息

• Process for producing tetrafluorophthalic anhydride
  申请人：Asahi Glass Company Ltd.

  公开号：US05648504A1

  公开（公告）日：1997-07-15

  A process for producing tetrafluorophthalic anhydride, which comprises chlorinating tetrachlorophthalic anhydride to obtain 3,3,4,5,6,7-hexachloro-1-[3H]-isobenzofuranone, then fluorinating it to obtain 3,4,5,6-tetrafluorophthaloyldifluoride and/or 3,3,4,5,6,7-hexafluoro-1-[3]-isobenzofuranone, and further reacting the tetrafluorophthalolyldifluoride and/or the hexafluoro-1-[3H]-isobenzofuranone with an inorganic base or an organic acid to obtain tetrafluorophthalic anhydride.

  一种生产四氟邻苯二甲酸酐的方法，包括将四氯邻苯二甲酸酐氯化以得到3,3,4,5,6,7-六氯-1-[3H]-异苯并呋喃酮，然后氟化它以得到3,4,5,6-四氟邻苯二甲酰二氟化物和/或3,3,4,5,6,7-六氟-1-[3]-异苯并呋喃酮，然后进一步将四氟邻苯二甲酰二氟化物和/或六氟-1-[3H]-异苯并呋喃酮与无机碱或有机酸反应以得到四氟邻苯二甲酸酐。
• Processes for producing tetrafluorophtahlic anhydride and fluorobenzoic acids
  申请人：ASAHI GLASS COMPANY LTD.

  公开号：EP0669310A1

  公开（公告）日：1995-08-30

  A process for producing tetrafluorophthalic anhydride, which comprises chlorinating tetrachlorophthalic anhydride to obtain 3,3,4,5,6,7-hexachloro-1-[3H]-isobenzofuranone, then fluorinating it to obtain 3,4,5,6-tetrafluorophthaloyldifluoride and/or 3,3,4,5,6,7-hexafluoro-1-[3H]-isobenzofuranone, and further reacting the tetrafluorophthalolyldifluoride and/or the hexafluoro-1-[3H]-isobenzofuranone with an inorganic base or an organic acid to obtain tetrafluorophthalic anhydride.

  一种生产四氟邻苯二甲酸酐的工艺，包括将四氯邻苯二甲酸酐氯化以获得 3,3,4,5,6,7-六氯-1-[3H]-异苯并呋喃酮，然后将其氟化以获得 3,4,5,6-四氟邻苯二甲酸二氟化物和/或 3、3,4,5,6,7-六氟-1-[3H]-异苯并呋喃酮，再将四氟邻苯二氟化物和/或六氟-1-[3H]-异苯并呋喃酮与无机碱或有机酸反应，得到四氟邻苯二甲酸酐。
• Processes for producing tetra-fluorophthalic anhydride and fluorobenzioc acids
  申请人：ASAHI GLASS COMPANY LTD.

  公开号：EP0866050A1

  公开（公告）日：1998-09-23

  A process for producing tetrafluorophthalic anhydride, which comprises chlorinating tetrachlorophthalic anhydride to obtain 3,3,4,5,6,7-hexachloro-1-[3H]-isobenzofuranone, then fluorinating it to obtain 3,4,5,6-tetrafluorophthaloyldifluoride and/or 3,3,4,5,6,7-hexafluoro-1-[3H]-isobenzofuranone, and further reacting the tetrafluorophthalolyldifluoride and/or the hexafluoro-1-[3H]-isobenzofuranone with an inorganic base or an organic acid to obtain tetrafluorophthalic anhydride.

  一种生产四氟邻苯二甲酸酐的工艺，包括将四氯邻苯二甲酸酐氯化以获得 3,3,4,5,6,7-六氯-1-[3H]-异苯并呋喃酮，然后将其氟化以获得 3,4,5,6-四氟邻苯二甲酸二氟化物和/或 3、3,4,5,6,7-六氟-1-[3H]-异苯并呋喃酮，再将四氟邻苯二氟化物和/或六氟-1-[3H]-异苯并呋喃酮与无机碱或有机酸反应，得到四氟邻苯二甲酸酐。
• Processes for producing tetra-fluorophthalic anhydride and fluorobenzoic acids
  申请人：ASAHI GLASS COMPANY LTD.

  公开号：EP0877011A1

  公开（公告）日：1998-11-11

  A process for producing tetrafluorophthalic anhydride, which comprises chlorinating tetrachlorophthalic anhydride to obtain 3,3,4,5,6,7-hexachloro-1-[3H]-isobenzofuranone, then fluorinating it to obtain 3,4,5,6-tetrafluorophthaloyldifluoride and/or 3,3,4,5,6,7-hexafluoro-1-[3H]-isobenzofuranone, and further reacting the tetrafluorophthalolyldifluoride and/or the hexafluoro-1-[3H]-isobenzofuranone with an inorganic base or an organic acid to obtain tetrafluorophthalic anhydride.

  一种生产四氟邻苯二甲酸酐的工艺，包括将四氯邻苯二甲酸酐氯化以获得 3,3,4,5,6,7-六氯-1-[3H]-异苯并呋喃酮，然后将其氟化以获得 3,4,5,6-四氟邻苯二甲酸二氟化物和/或 3、3,4,5,6,7-六氟-1-[3H]-异苯并呋喃酮，再将四氟邻苯二氟化物和/或六氟-1-[3H]-异苯并呋喃酮与无机碱或有机酸反应，得到四氟邻苯二甲酸酐。
• Oxygen replacement by fluorine in carbonyl derivatives of perfluoroaromatic compounds and isomerization of perfluoroindan-1,3-dione to perfluoro-3-methylenephthalide under the action of HF/SbF5
  作者：Yaroslav V. Zonov、Victor M. Karpov、Vyacheslav E. Platonov、Tatjana V. Rybalova、Yuri V. Gatilov

  DOI：10.1016/j.jfluchem.2006.08.006

  日期：2006.12

  When acted upon by HF/SbF5 at 95 degrees C, carbonyl groups of perfluorinated acetophenone (10), 3,4-dihydronaphthalen-1(2H)-one (8), 2,3-dihydronaphthalene-1,4-dione (9), benzocyclobutenone (6), benzocyclobutenedione (7) and indan-l-one (1) are converted into difluoromethylene groups to give the corresponding perfluoroaromatic products. Perfluoroindan-2-one (5), under the same conditions, is transformed to bis(perfluoroindan-2-yl) ether (21). On heating with HF/SbF5, perfluoroindan-1,3-dione (2) isomerizes into perfluoro-3-methylenephthalide (4) at 95 degrees C, and gives 4,5,6,7-tetrafluoro-3-trifluoromethyl-phthalide (14) at 130 degrees C. Compound 4 in the absence of a solvent dimerizes giving perfluorodispiro[phthalide-3,1 '-cyclobutane-2 ',3 ''-phthalide] (18), and when heated with SbF5 at 130 degrees C, it is converted into perfluoro-3-methylphthalide (3). When acted upon by HF/SbF5 at 95 degrees C, perfluorinated benzoic acid (12) and phthalic anhydride (13) give the corresponding products with trifluoromethyl groups. (c) 2006 Elsevier B.V. All rights reserved.