2,5-bis(4-(bis(pyridin-2-ylmethyl)amino)styryl)terephthalonitrile | 1555883-05-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 2,5-bis(4-(bis(pyridin-2-ylmethyl)amino)styryl)terephthalonitrile
• CAS: 1555883-05-0
• 化学式: C₄₈H₃₈N₈
• 分子量: 726.883
• InChiKey: OHFOWJUYOWQZJG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.76
• 重原子数：
  56.0
• 可旋转键数：
  14.0
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  105.62
• 氢给体数：
  0.0
• 氢受体数：
  8.0

反应信息

• 作为产物：
  描述：

  苯胺 在 十六烷基三甲基氯化铵 、 sodium hydride 、 sodium hydroxide 、 三氯氧磷 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 41.33h， 生成 2,5-bis(4-(bis(pyridin-2-ylmethyl)amino)styryl)terephthalonitrile
  参考文献：
  名称：

  Ratiometric and selective two-photon fluorescent probe based on PET-ICT for imaging Zn2+ in living cells and tissues

  摘要：

  A two-photon fluorescent probe TPZn was developed for specific ratiometric imaging Zn2+ in living cells and tissues. Significant ratiometric fluorescence change was based on photoinduced electron transfer and intramolecular charge transfer. The synthetic method of TPZn was simple. It was successfully used to selectively image Zn2+ based on the higher binding affinity for Zn2+ than for Cd2+. TPZn was easily loaded into the living cell and tissues with high membrane permeability in a complex biological environment. TPZn could clearly visualize endogenous Zn2+ by TP ratiometric imaging in hippocampal slices at a depth of 120 mu m. Thus, TPZn is a useful tool to image of Zn2+ in living cells and tissues without interference from Cd2+. (C) 2013 Shang Wu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  DOI：

  10.1016/j.cclet.2013.10.005