4-chloro-[2]naphthoic acid | 1013-81-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4-chloro-[2]naphthoic acid
• 英文别名: 4-Chlor-[2]naphthoesaeure；2-Naphthalenecarboxylic acid, 4-chloro-；4-chloronaphthalene-2-carboxylic acid
• CAS: 1013-81-6
• 化学式: C₁₁H₇ClO₂
• 分子量: 206.628
• InChiKey: UFRIHZIEDMPEQT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2916399090

反应信息

• 作为产物：
  描述：

  3-amino-4-nitro-[2]naphthoic acid 在 硫酸 、 溶剂黄146 、 sodium nitrite 作用下， 生成 4-chloro-[2]naphthoic acid
  参考文献：
  名称：

  Adcock,W.; Wells,P.R., Australian Journal of Chemistry, 1965, vol. 18, p. 1351 - 1364

  摘要：

  DOI：

文献信息

• Preparation of esters of mono- or dicarboxylic non-aromatic and aromatic acids
  申请人：Lonza Ltd

  公开号：EP2465841A1

  公开（公告）日：2012-06-20

  The present invention relates to a method for preparing a carboxylic acid ester, wherein a carboxylic acid and/or a salt thereof is reacted with an alcohol in the presence of hydrogen chloride (HCl) and water to form the carboxylic acid ester, wherein the reaction is carried out using a starting reaction system wherein the molar ratio of HCl to carboxylic acid is at least 0.075 : 1 and the molar ratio of water to carboxylic acid is at least 0.25 : 1.

  本发明涉及一种制备羧酸酯的方法，其中在氯化氢（HCl）和水的存在下，羧酸和/或其盐与醇反应，形成羧酸酯，其中该反应是在使用起始反应体系的情况下进行的，其中氯化氢与羧酸的摩尔比至少为0.075：1，水与羧酸的摩尔比至少为0.25：1。
• Preparation of benzylthiazolidine derivatives
  申请人：Sankyo Company Limited

  公开号：EP0839812A1

  公开（公告）日：1998-05-06

  A process for preparing a compound of formula (Ia): [in which R1, R2 and R5 are each hydrogen or alkyl; R3 and R4 are each hydrogen, alkyl, formyl, alkylcarbonyl, arylcarbonyl, carboxy, alkoxycarbonyl, aryloxycarbonyl, hydroxy, alkylcarbonyloxy, formyloxy, arylcarbonyloxy, optionally substituted alkoxy or halogen; W is methylene, carbonyl or a group of formula >C=N-OV, in which V is hydrogen, alkylcarbonyl, arylcarbonyl or optionally substituted alkyl; and n is an integer of from 1 to 3] or a salt thereof by reduction of a compound of formula (I): or a salt thereof, in which R1 to R5, W and n are as defined above.

  一种制备式 (Ia) 化合物的工艺： [其中 R1、R2 和 R5 分别为氢或烷基；R3 和 R4 分别为氢、烷基、甲酰基、烷基羰基、芳基羰基、羧基、烷氧基羰基、芳氧基羰基、羟基、烷基羰氧基、甲酰基氧基、芳基羰氧基、任选取代的烷氧基或卤素；W 是亚甲基、羰基或式 >C=N-OV 的基团，其中 V 是氢、烷基羰基、芳基羰基或任选取代的烷基；以及 n 是 1 至 3 的整数]或通过还原式（I）化合物而得到的盐： 或其盐，其中 R1 至 R5、W 和 n 如上文所定义。
• Egg Production, Fertility, and Hatchability of Breeder Hens Receiving Dietary Phytase
  作者：W.D. Berry、J.B. Hess、R.J. Lien、D.A. Roland

  DOI：10.1093/japr/12.3.264

  日期：2003.10

  An experiment was conducted to determine whether supplemental dietary phytase could support egg production, egg shell quality, fertility, and hatchability in broiler breeder hens on a diet with marginal available phosphorus. During the production period, 27 to 60 wk of age, individually caged broiler breeder hens; were fed four diets with two available phosphorus (AP) concentrations (0.1 and 0.3%) and two phytase levels [0 and 300 phytase units (FTU)/kg]. Phytase increased overall hen-day egg production by 9.8%, as compared with hens consuming a low phosphorus diet without added phytase. Addition of phytase significantly reduced hen mortality regardless of AP levels. Phytase improved bone mineral content and bone density of hens at both AP levels. Supplemental phytase had no significant effect on egg weight or egg specific gravity. The results suggest the possibility of a detrimental interaction of phytase with the 0.1 AP level on hatchability.
• KOZYREVA N. P.; BEXLI A. F., XIMIYA GETEROTSIKL. SOEDIN. <KGSS-AQ>, 1975, HO 4, 520-522
  作者：KOZYREVA N. P.、 BEXLI A. F.

  DOI：——

  日期：——
• 17 a?$g(b)-HYDROXY-7$g(a)-METHYL-D-HOMO-19-NORANDROST-4,16-DIENE-3-ONE AND THE 17-ESTERS THEREOF: METHODS OF PREPARATION AND USES
  申请人：SRI INTERNATIONAL

  公开号：EP0182808A1

  公开（公告）日：1986-06-04