diisopentyl-methyl-amine | 10471-21-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: diisopentyl-methyl-amine
• 英文别名: N,N-Diisopentylmethylamine；N,3-dimethyl-N-(3-methylbutyl)butan-1-amine
• CAS: 10471-21-3
• 化学式: C₁₁H₂₅N
• 分子量: 171.326
• InChiKey: MBROYQPTQBQIPC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  溴乙烷 、 diisopentyl-methyl-amine 在 丁酮 作用下， 生成 ethyl-diisopentyl-methyl-ammonium; bromide
  参考文献：
  名称：

  Autonomic Blocking Agents. I. Branched Aliphatic Quaternary Ammonium and Analogous Cyclic Ammonium Salts

  摘要：

  DOI：

  10.1021/jo50006a014
• 作为产物：
  描述：

  聚合甲醛 、 甲酸 、 二异戊胺 生成 diisopentyl-methyl-amine
  参考文献：
  名称：

  Autonomic Blocking Agents. I. Branched Aliphatic Quaternary Ammonium and Analogous Cyclic Ammonium Salts

  摘要：

  DOI：

  10.1021/jo50006a014

文献信息

• DERIVATIVES OF 2-PYRIDIN-2-YL-PYRAZOL-3(2H)-ONE, PREPARATION AND THERAPEUTIC USE THEREOF AS HIF ACTIVATORS
  申请人：ALTENBURGER Jean-Michel

  公开号：US20110294788A1

  公开（公告）日：2011-12-01

  The present invention relates to novel substituted dihydropyrazolone derivatives, to their preparation and to their therapeutic use as activators of the transcription factor HIF.

  本发明涉及新型取代二氢吡唑酮衍生物，其制备以及作为转录因子HIF激活剂的治疗用途。
• THERAPEUTIC COMPOUNDS AND COMPOSITIONS
  申请人：eXIthera Pharmaceuticals Inc.

  公开号：US20150225389A1

  公开（公告）日：2015-08-13

  The present invention provides compounds and compositions that inhibit Factor XIa or kallikrein and methods of using these compounds and composition.

  本发明提供了抑制XIa因子或激肽酶的化合物和组合物，以及使用这些化合物和组合物的方法。
• [EN] SOLVENTS<br/>[FR] SOLVANTS
  申请人：BIONIQS LTD

  公开号：WO2009034329A1

  公开（公告）日：2009-03-19

  There is described the use of a protic ionic liquid comprising a trialkylammonium salt as a solvent.

  这里描述了一种包含三烷基铵盐的质子离子液体作为溶剂的使用。
• BIS(6-METHYL-3-SULPHOPHENYL)PHENYLPHOSPHINE, AMMONIUM SALT THEREOF, AND METHOD FOR PRODUCING SAME
  申请人：HOKKO CHEMICAL INDUSTRY CO., LTD.

  公开号：US20160052947A1

  公开（公告）日：2016-02-25

  Provided are a water-soluble triarylphosphine for a palladium catalyst, which has high selectivity in a telomerization reaction and can be recovered with efficiency, an ammonium salt thereof, and a method for efficiently producing the same. Specifically, provided are bis(6-methyl-3-sulphophenyl)phenylphosphine; a bis(6-methyl-3-sulphonatophenyl)phenylphosphine diammonium salt obtained by reacting the phosphine with a tertiary amine having a total of 3 to 27 carbon atoms in groups bonded to one nitrogen atom; and a method for producing the same.

  提供了一种水溶性三芳基膦钯催化剂，其在缩聚反应中具有高选择性，并且可以高效回收，以及其铵盐，以及一种高效生产该化合物的方法。具体提供了双(6-甲基-3-磺酸苯基)苯基膦；通过将膦与含有3至27个碳原子的基团与一个氮原子键合的三级胺反应而得到的双(6-甲基-3-磺酸苯基)苯基膦二铵盐；以及一种生产该化合物的方法。
• METHOD FOR PRODUCING 2,7-OCTADIEN-1-OL
  申请人：KURARAY CO., LTD.

  公开号：US20160046549A1

  公开（公告）日：2016-02-18

  Provided is a simple and industrially advantageous method for producing 2,7-octadien-1-ol, in which an expensive palladium catalyst is recovered in high efficiency and the reaction rate per atom of palladium is enhanced. Specifically, provided is a method for producing 2,7-octadien-1-ol by subjecting butadiene and water to a telomerization in the presence of a palladium catalyst containing a water-soluble triarylphosphine having two or more sulfonate groups in the molecule and a palladium compound, a tertiary amine, and carbon dioxide, including a step of mixing the telomerization solution obtained by the telomerization with an organic solvent having a dielectric constant at 25° C. of 2 to 18, followed by carrying out phase separation in the presence of carbon dioxide, thereby obtaining 2,7-octadien-1-ol from an organic phase while recovering an aqueous phase including the palladium catalyst. By this production method, the selectivity for 2,7-octadien-1-ol is enhanced.

  提供了一种简单且在工业上具有优势的生产2,7-辛二烯-1-醇的方法，其中昂贵的钯催化剂以高效率回收，并且增强了每个钯原子的反应速率。具体而言，提供了一种通过在存在包含具有两个或更多磺酸基团的水溶性三芳基膦和钯化合物、三级胺和二氧化碳的钯催化剂的情况下，使丁二烯和水经过缩聚反应来生产2,7-辛二烯-1-醇的方法，包括将通过缩聚反应获得的缩聚溶液与在25°C时具有介电常数为2到18的有机溶剂混合的步骤，然后在二氧化碳的存在下进行相分离，从而从有机相中获得2,7-辛二烯-1-醇，同时回收包括钯催化剂的水相。通过这种生产方法，对2,7-辛二烯-1-醇的选择性得到增强。