There are disclosed benzothiadiazinyl and quinazolinyl substituted carboxylalkyl dipeptides, wherein the benzothiodiazinyl or quinazolinyl portions are joined to the dipeptide portions by an aminocarbonyl group. Compounds of this invention are useful as antihypertensive agents, in the treatment of congestive heart failure and in the treatment of glaucoma. In addition, compounds of this invention have diuretic activity.
本发明公开了苯并噻二嗪基和
喹唑啉基取代的羧基烷基二肽,其中苯并噻二嗪基或
喹唑啉基部分通过
氨基羰基团连接到二肽部分。本发明的化合物可用作降压剂,在治疗充血性心力衰竭和青光眼方面有用。此外,本发明的化合物具有利尿作用。