Neopentylphosphonsaeuredimethylester | 54552-76-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: Neopentylphosphonsaeuredimethylester
• 英文别名: 1-Dimethoxyphosphoryl-2,2-dimethylpropane
• CAS: 54552-76-0
• 化学式: C₇H₁₇O₃P
• 分子量: 180.184
• InChiKey: RKPGPOKUWQMRSL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  Neopentylphosphonsaeuredichlorid 在 三乙胺 作用下， 生成 Neopentylphosphonsaeuredimethylester
  参考文献：
  名称：

  Hilbert,C. et al., Journal fur praktische Chemie (Leipzig 1954), 1974, vol. 316, p. 790 - 794

  摘要：

  DOI：

文献信息

• NONAQUEOUS ELECTROLYTE SOLUTION CONTAINING SILYL ESTER GROUP-CONTAINING PHOSPHONIC ACID DERIVATIVE, AND LITHIUM SECONDARY BATTERY
  申请人：Kobayashi Takeshi

  公开号：US20130071732A1

  公开（公告）日：2013-03-21

  The present invention provides a non-aqueous electrolyte solution which contains a silyl ester group-containing phosphonic acid derivative.

  本发明提供了一种含有硅酯基磷酸衍生物的非水电解质溶液。
• PHOSPHONATE COMPOUNDS HAVING IMMUNO-MODULATORY ACTIVITY
  申请人：Cannizzaro Carina

  公开号：US20090227543A1

  公开（公告）日：2009-09-10

  The invention is related to phosphonate substituted compounds having immuno-modulatory activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

  本发明涉及磷酸酯取代化合物，具有免疫调节活性，含有这种化合物的组合物，以及包括这种化合物的给药的治疗方法，还涉及用于制备这种化合物的有用过程和中间体。
• Antiviral Compounds
  申请人：Boojamra Constantine G.

  公开号：US20090012037A1

  公开（公告）日：2009-01-08

  The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

  本发明涉及磷取代的抗病毒抑制化合物、含有这些化合物的组合物以及包括这些化合物的治疗方法，还涉及用于制备这些化合物的过程和中间体。
• Pre-organized tricyclic integrase inhibitor compounds
  申请人：Chen James M.

  公开号：US20090029939A1

  公开（公告）日：2009-01-29

  Tricyclic compounds according to the structure below, protected intermediates thereof, and methods for inhibition of HIV-integrase are disclosed. A 1 and A 2 are moieties forming a five, six, or seven membered ring. L is a bond or a linker connecting a ring atom of Ar to N. X is O, S, or substituted nitrogen. Ar is aryl or heteroaryl, Q is N, + NR, or CR 4 . The aryl carbons may be independently substituted with substituents other than hydrogen. The compounds may include prodrug moieties covalently attached at any site.

  本发明揭示了以下结构的三环化合物、其保护中间体以及抑制HIV整合酶的方法。其中，A1和A2是形成五、六或七元环的基团。L是连接Ar环原子和N的键或连接剂。X是O、S或取代的氮。Ar是芳基或杂环芳基，Q是N、+NR或CR4。芳基碳可以独立地被取代为除氢以外的取代基。这些化合物可以包括共价连接在任何位置的前药基团。
• Antiviral compounds
  申请人：Cai Zhenhong R.

  公开号：US20080076740A1

  公开（公告）日：2008-03-27

  The invention is related to phosphorus substituted anti-viral inhibitory compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

  该发明涉及磷取代的抗病毒抑制化合物、含有该化合物的组合物、包括给予该化合物的治疗方法，以及用于制备该化合物的有用过程和中间体。