4-((S)-2-Methyl-butoxy)-3,5-dioxa-4-phospha-cyclohepta[2,1-a;3,4-a']dinaphthalene | 208923-93-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4-((S)-2-Methyl-butoxy)-3,5-dioxa-4-phospha-cyclohepta[2,1-a;3,4-a']dinaphthalene
• CAS: 208923-93-7
• 化学式: C₂₅H₂₃O₃P
• 分子量: 402.43
• InChiKey: HTUAOAHNPYOTKH-KRWDZBQOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.07
• 重原子数：
  29.0
• 可旋转键数：
  4.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  35.51
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  4-((S)-2-Methyl-butoxy)-3,5-dioxa-4-phospha-cyclohepta[2,1-a;3,4-a']dinaphthalene 在 1,2,3,4,5,6,7,8-八硫杂环辛烷 作用下， 生成
  参考文献：
  名称：

  On the use of seven-membered phosphorous heterocycles based on 2,2′-dihydroxy-1,1′-binaphthalene and 1,4∶3,6-dianhydro-d-mannitol in the31P NMR analysis of the enantiomeric composition of chiral alcohols

  摘要：

  Some aspects of phosphorylation of 2,2'-dihydroxy-1,1'-binaphthalene (BINOL) and 1,4:3,6-dianhydro-D-mannitol (isomannide) were investigated. The possibility of using the corresponding cyclic chloro-and amidophosphites for the analysis of enantiomeric compositions of chiral primary and secondary alcohols by P-31 NMR was examined.

  DOI：

  10.1007/bf02495644
• 作为产物：
  描述：

  S-1,1'-联-2-萘酚 、 alkaline earth salt of/the/ methylsulfuric acid 在 三乙胺 、 三氯化磷 作用下， 以 甲苯 为溶剂， 反应 12.17h， 生成 4-((S)-2-Methyl-butoxy)-3,5-dioxa-4-phospha-cyclohepta[2,1-a;3,4-a']dinaphthalene
  参考文献：
  名称：

  On the use of seven-membered phosphorous heterocycles based on 2,2′-dihydroxy-1,1′-binaphthalene and 1,4∶3,6-dianhydro-d-mannitol in the31P NMR analysis of the enantiomeric composition of chiral alcohols

  摘要：

  Some aspects of phosphorylation of 2,2'-dihydroxy-1,1'-binaphthalene (BINOL) and 1,4:3,6-dianhydro-D-mannitol (isomannide) were investigated. The possibility of using the corresponding cyclic chloro-and amidophosphites for the analysis of enantiomeric compositions of chiral primary and secondary alcohols by P-31 NMR was examined.

  DOI：

  10.1007/bf02495644

文献信息

• ——
  作者：Z. A. Bredikhina、V. G. Novikova、N. M. Azancheev、A. A. Bredikhin

  DOI：10.1023/a:1020815410142

  日期：——

  The regioisomeric composition of the adducts of unsymmetrical oxiranes with achiral and chiral phosphorochloridites was studied. Factors allowing enantiomeric assessment of chiral oxiranes with the aid of chiral derivatizing organophosphorus reagents were revealed.