2-vinylbenzopyrazole | 22499-45-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡唑类
• 英文名称: 2-vinylbenzopyrazole
• 英文别名: 2-Vinylindazole；2-vinyl-2H-indazole；2-Vinyl-2H-indazol；2-Venylwidazol；2-ethenylindazole
• CAS: 22499-45-2
• 化学式: C₉H₈N₂
• 分子量: 144.176
• InChiKey: IJGBQZWGRCCKFB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  17.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-vinylbenzopyrazole 在 溴 作用下， 以 四氯化碳 为溶剂， 以92%的产率得到2-(1',2'-dibromoethyl)indazole
  参考文献：
  名称：

  Bromination of vinylindazoles

  摘要：

  DOI：

  10.1007/bf00954437
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 sodium hydroxide 作用下， 生成 2-vinylbenzopyrazole
  参考文献：
  名称：

  v. Auwers; Kleiner, Journal fur praktische Chemie (Leipzig 1954), 1928, vol. <2> 118, p. 74,90

  摘要：

  DOI：

文献信息

• NMR investigation of chlorophosphorylation products of <i>N</i> -vinylazoles
  作者：Lyudmila I. Larina、Vladimir G. Rozinov、Mikhail Yu. Dmitrichenko、Lyudmila A. Es'kova

  DOI：10.1002/mrc.2367

  日期：2009.2

  phosphorus‐containing N‐vinylazoles prepared by action of phosphorus pentachloride has been studied by multinuclear 1H, 13C, 15N, 31P and two‐dimensional (2D) NMR spectroscopy. N‐vinyl‐substituted 1,2‐diazoles and 1,2,3‐triazoles have undergone phosphorylation, exclusively, on double bond. N‐vinylazoles‐based hexa‐coordinated phosphorus compounds have been synthesized for the first time. 31P NMR spectroscopy

  通过多核 1H、13C、15N、31P 和二维 (2D) NMR 光谱研究了通过五氯化磷作用制备的新型含磷 N-乙烯基唑的结构。N-乙烯基取代的 1,2-二唑和 1,2,3-三唑仅在双键上发生磷酸化。首次合成了基于 N-乙烯基唑的六配位磷化合物。31P NMR 光谱为研究磷酸化烯胺的 E-Z-异构结构提供了最方便和明确的方法。版权所有 © 2008 John Wiley & Sons, Ltd.
• Synthesis of Annulated 2<i>H</i>-Indazoles and 1,2,3- and 1,2,4-Triazoles via a One-Pot Palladium-Catalyzed Alkylation/Direct Arylation Reaction
  作者：Benoît Laleu、Mark Lautens

  DOI：10.1021/jo8017236

  日期：2008.11.21

  A variety of six-membered-ring annulated 2H-indazoles and 1,2,3- and 1,2,4-triazoles were synthesized in good to excellent yields from the corresponding bromoethyl azoles and aryl iodides. The annulation process involves a one-pot norbornene-mediated palladium-catalyzed sequence whereby an alkyl-aryl bond and an aryl-heteroaryl bond are successively formed through two C-H bond activations. Subsequent

  从相应的溴乙基唑和芳基碘化物以良好至优异的收率合成了多种六元环环状的2H-吲唑以及1,2,3-和1,2,4-三唑。环合过程涉及一锅降冰片烯介导的钯催化的序列，其中烷基-芳基键和芳基-杂芳基键通过两次CH键激活连续形成。还介绍了通过交叉偶联反应对所得多环化合物的后续官能化作用。
• MANUFACTURING METHOD FOR TIRE CORD AND ADHESIVE MATERIAL FOR TIRE CORD
  申请人：Bridgestone Corporation

  公开号：EP1657354A1

  公开（公告）日：2006-05-17

  There is provided a novel production method for a tire cord capable of suppressing the use of a diluent accompanying the fuming of harmful substances and energy consumption. The production of a tire cord 7 comprising a twisted cord 6 and an adhesive layer for rubber on the surface of the twisted cord 6 is characterized by comprising a step of spraying an adhesive material onto the twisted cord 6 for coating. A coating apparatus 1 can be used. The coating apparatus 1 comprises a plurality of coaters 2 for spraying an adhesive onto the surface of the twisted cord 6. The coater 2 comprises a coating nozzle and a coating guide. The coating apparatus 1 further comprises an interlacer 3, a low speed pump 4 and an adhesive tank 5 filled with the adhesive.

  本发明提供了一种新颖的轮胎帘线生产方法，该方法能够减少稀释剂的使用以及有害物质的发烟和能源消耗。轮胎帘子线 7 的生产包括加捻帘子线 6 和加捻帘子线 6 表面的橡胶粘合剂层，其特征在于包括在加捻帘子线 6 上喷涂粘合剂材料的步骤。可以使用涂布装置 1。涂覆装置 1 包括多个涂覆器 2，用于将粘合剂喷涂到加捻帘线 6 的表面。涂布器 2 包括一个涂布喷嘴和一个涂布导向器。涂布装置 1 还包括一个夹层器 3、一个低速泵 4 和一个装满粘合剂的粘合剂罐 5。
• Adhesive composition and process for adhesion using the adhesive composition
  申请人：Bridgestone Corporation

  公开号：EP1757667A2

  公开（公告）日：2007-02-28

  The present invention provides an adhesive composition exhibiting a great adhesive strength between an adherend and an adhesive composition and providing remarkably improved workability in attaching a sheet of an unvulcanized rubber composition by forming a hardened surface of an adhesive layer comprising the adhesive composition and a process for adhesion using the adhesive. The adhesive composition comprises a conjugated diene-based polymer (A) having at least one functional group having a photo-curable unsaturated hydrocarbon group at a chain end, a polymerizable compound (B), a photopolymerization initiator (C) and at least one of an active energy ray-shielding agent (D1) and a metal and/or metal compound (D2).

  本发明提供了一种粘合剂组合物，通过形成包含该粘合剂组合物的粘合剂层的硬化表面和使用该粘合剂的粘合工艺，在被粘物和粘合剂组合物之间显示出很高的粘合强度，并在粘合未硫化橡胶组合物薄片时提供显著改善的可操作性。粘合剂组合物包括共轭二烯基聚合物 (A)，其至少一个官能团的链端具有光固化不饱和烃基；可聚合化合物 (B)；光聚合引发剂 (C)；以及活性能量射线屏蔽剂 (D1) 和金属和/或金属化合物 (D2) 中的至少一种。
• Responsive microgel and methods related thereto
  申请人：——

  公开号：US20030152623A1

  公开（公告）日：2003-08-14

  A responsive microgel is provided which responds volumetrically and reversibly to a change in one or more aqueous conditions selected from the group consisting of (temperature, pH, and ionic conditions) comprised of an ionizable network of covalently cross-linked homopolymeric ionizable monomers wherein the ionizable network is covalently attached to an amphiphilic copolymer to form a plurality of ‘dangling chains’ and wherein the ‘dangling chains’ of amphiphilic copolymer form immobile micelle-like aggregates in aqueous solution. A responsive microgel is further provided that comprises at least one therapeutic entity and delivers a substantially linear and sustained release of the therapeutic entity under physiological conditions.

  本发明提供了一种响应型微凝胶，该微凝胶可对选自由温度、pH 值和离子条件组成的组中的一种或多种水性条件的变化作出体积上和可逆的响应、和离子条件）组成的共价交联均聚可离子化单体的可离子化网络，其中可离子化网络与两性共聚物共价连接，形成多条 "悬链"，两性共聚物的 "悬链 "在水溶液中形成不动的胶束状聚集体。还提供了一种响应性微凝胶，它包含至少一种治疗实体，并能在生理条件下提供治疗实体的线性和持续释放。

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