methyl 1,8-dihydroxy-6-(ethoxycarbonyl)-2-(methoxycarbonyl)-3-naphthylacetate | 107182-07-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: methyl 1,8-dihydroxy-6-(ethoxycarbonyl)-2-(methoxycarbonyl)-3-naphthylacetate
• 英文别名: 6-O-ethyl 2-O-methyl 1,8-dihydroxy-3-(2-methoxy-2-oxoethyl)naphthalene-2,6-dicarboxylate
• CAS: 107182-07-0
• 化学式: C₁₈H₁₈O₈
• 分子量: 362.336
• InChiKey: QSMBIRQVNKDCMF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  26
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  119
• 氢给体数：
  2
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  柠檬酸三乙酯 、 乙酰乙酸甲酯 在 正丁基锂 、 calcium acetate 、 sodium hydride 作用下， 生成 methyl 1,8-dihydroxy-6-(ethoxycarbonyl)-2-(methoxycarbonyl)-3-naphthylacetate
  参考文献：
  名称：

  A synthesis of polycyclic aromatic compounds by the calcium acetate-induced aromatization of polyoxoalkanedioates generated from diesters and acetoacetate dianion

  摘要：

  DOI：

  10.1021/jo00292a041

文献信息

• A biomimetic synthesis of polycyclic polyoxygenated aromatic compounds via polyketides
  作者：Masahiko Yamaguchi、Koichi Hasebe、Toru Minami

  DOI：10.1016/s0040-4039(00)84540-2

  日期：——

  Polyoxygenated naphthalenes, anthracenes and a naphthacene are synthesized from glutarates and acetoacetate dianion via polyketides.

  由戊二酸酯和乙酰乙酸二酯经聚酮化合物合成多氧化萘，蒽和并四苯。
• YAMAGUCHI MASAHIKO; HASEBE KOICHI; MINAMI TORU, TETRAHEDRON LETT., 27,(1986) N 21, 2401-2404
  作者：YAMAGUCHI MASAHIKO、 HASEBE KOICHI、 MINAMI TORU

  DOI：——

  日期：——
• COMPOSITION COMPRISING AT LEAST ONE 1,8-DIHYDROXYNAPHTHALENE DERIVATIVE AND AT LEAST ONE BASIFYING AGENT DIFFERENT FROM AQUEOUS AMMONIA, PROCESS FOR DYEING KERATIN FIBRES USING THE COMPOSITION
  申请人：L'Oréal

  公开号：EP2488152B1

  公开（公告）日：2018-04-04
• US8551189B2
  申请人：——

  公开号：US8551189B2

  公开（公告）日：2013-10-08
• [EN] COMPOSITION COMPRISING AT LEAST ONE 1,8-DIHYDROXYNAPHTHALENE DERIVATIVE AND AT LEAST ONE BASIFYING AGENT DIFFERENT FROM AQUEOUS AMMONIA, PROCESS FOR DYEING KERATIN FIBRES USING THE COMPOSITION<br/>[FR] COMPOSITION COMPRENANT AU MOINS UN DÉRIVÉ 1,8-DIHYDROXYNAPHTHALÈNE ET AU MOINS UN AGENT DE BASIFICATION DIFFÉRENT D'AMMONIAQUE AQUEUX, PROCÉDÉ DESTINÉ À COLORER DES FIBRES DE KÉRATINE AU MOYEN DE LA COMPOSITION
  申请人：OREAL

  公开号：WO2011045403A2

  公开（公告）日：2011-04-21

  The subject of the invention is a composition for dyeing keratin fibres, comprising at least one 1,8-dihydroxynaphthalene derivative and at least one basifying agent other than aqueous ammonia; the use of the composition for hair dyeing and also the use of the composition in a dyeing process for keratin fibres. The composition according to the invention makes it possible to dye keratin fibres under mild oxidizing conditions even without using an oxidation base and an aromatic amine, while at the same time covering a broad colour range with 1,8-dihydroxynaphthalene derivatives. The observed dyeing under oxidizing conditions operates under mild conditions of oxidation and/or basifying agent, in particular in the air, and does not produce any unpleasant odour.