3-(4-methoxyphenyl)-3-trichlorogermylpropionic acid | 136025-99-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: 3-(4-methoxyphenyl)-3-trichlorogermylpropionic acid
• 英文别名: 3-(4-methoxyphenyl)-3-trichlorogermylpropanoic acid
• CAS: 136025-99-5
• 化学式: C₁₀H₁₁Cl₃GeO₃
• 分子量: 358.145
• InChiKey: PJPZJMMVJSVWJM-UHFFFAOYSA-N

物化性质

• 熔点：
  109-111 °C
• 沸点：
  407.0±55.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.45
• 重原子数：
  17.0
• 可旋转键数：
  5.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  46.53
• 氢给体数：
  1.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  3-(4-methoxyphenyl)-3-trichlorogermylpropionic acid 、 苯基溴化镁 以 四氢呋喃 为溶剂， 生成 Ph3GeCH(p-CH3C6H4)CH2COOH
  参考文献：
  名称：

  Synthesis, Spectral (FT‐IR, ¹H, ¹³C, ¹¹⁹Sn) and Biological Studies of Bimetallic Trimethyltin(IV) Germapropionates: X‐Ray Structure of (CH₃)₃Sn(C₂₂H₂₁O₂Ge)

  摘要：

  New compounds of bimetallic trimethyltin(IV) germapropionates have been synthesized and characterized by elemental analyses, FT-IR, and multinuclear nmr (H-1,C-13,Sn-119) spectroscopies. These compounds show four-coordinated structure in solution and penta-coordinated structure in solid state. The crystal structure of representative compound, (CH3)(3)Sn(C-22 H-21 O-2 Ge), shows one dimensional polymeric penta-coordinated structure in its solid state. The synthesized compounds were subjected for a bioassay screening and show promising antibacterial and antifungal activities.

  DOI：

  10.1080/15533170701301470
• 作为产物：
  描述：

  反式-4-甲氧基肉桂酸 、 盐酸 生成 3-(4-methoxyphenyl)-3-trichlorogermylpropionic acid
  参考文献：
  名称：

  SUN, LI-JUAN;WU, YU-SHENG;BAI, MING-ZHANG, YUTSZI XU SYUEH, 11,(1991) N, S. 303-306

  摘要：

  DOI：

文献信息

• SYNTHESIS AND CHARACTERIZATION OF DIORGANOTIN COMPOUNDS CONTAINING SILICON AND GERMANIUM AND CRYSTAL STRUCTURE OF PRECURSOR CARBOXY-ETHYLTRICHLOROGERMANIUM
  作者：M. Aziz Choudhary、M. Mazhar、U. Salma、S. Ali、X. Qinglan、K. C. Molloy

  DOI：10.1081/sim-100002047

  日期：2001.2.28

  Eight compounds of general formula [R-1(CH3)(2)SiCH2](2)Sn-[O2CCH2(R-2)CHGeR33](2) [R-1 = CH3, C2H5; R-2 = C6H5, C6H4OMe-3/4, R-3 = CH3, N(CH2CH2O)(3)] have been synthesised from [R-1 (CH3)(2)SiCH2](2)SnCl2 and R-3(3) GeCH(R-2)CH2CO2H in the presence of triethylamine. (Me-3 CCH2)(3)SnO2CCH2(R-1)CHGe(R-2)(3) [R-1 = C6H5, C6H4OMe-3; R-2 = N(CH2CH2O)(3)] have been synthesised similarly from (Me3CCH2)(3)SnCl. The compounds have been characterised by H-1, C-13, Si-29 and Sn-119 NMR. The structure of a precursor, Cl3GeCH(Ph)CH2CO2H, has been re-determined and shown to be a hydrogen-bonded dimer rather than a monomer as previously described.