1,4-bis-(4-bromo-phenyl)-piperazine | 65018-25-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 1,4-bis-(4-bromo-phenyl)-piperazine
• 英文别名: 1,4-Bis-(4-brom-phenyl)-piperazin；1,4-Bis(4-bromophenyl)piperazine
• CAS: 65018-25-9
• 化学式: C₁₆H₁₆Br₂N₂
• 分子量: 396.124
• InChiKey: RZBGWXXKTYPCQX-UHFFFAOYSA-N

物化性质

• 沸点：
  497.6±45.0 °C(Predicted)
• 密度：
  1.588±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,4-bis-(4-bromo-phenyl)-piperazine 在 bis-triphenylphosphine-palladium(II) chloride 、 copper(l) iodide 、 potassium carbonate 作用下， 生成 1,4-bis(4-ethynylphenyl)piperazine
  参考文献：
  名称：

  Photoinduced Electron Transfer as a Probe for the Folding Behavior of Dimethylsilylene-Spaced Alternating Donor–Acceptor Oligomers and Polymers

  摘要：

  A series of oligomers and polymers having dimethylsilylene-spaced alternating 4-aminostyrene donor and stilbene acceptor chromophores (two to one) are regioselectively synthesized, and the two donor chromophores are separated by different bridges between two donors. Photophysical tools have been used to examine the folding behavior of these copolymers. Both steady-state and time-resolved fluorescence spectroscopic measurements were examined. The relative intensities (I-CT/I-LE) between emission from charge-separated state (CT emission) and local excited emission of acceptor chromophore (LE emission) increase with increasing number of repeating units, and reach a plateau, when the linkers between the two aminostyrene chromophores are trimethylene bridges. Replacements of these by dimethylene or tetramethylene linker reduce the relative intensities of CT emission of the polymers, owing to the different folding behavior of these polymers. The CT emission intensity of the polymer with rigid piperazine linkers is much lower than that with trimethylene-bridged copolymer of the same degree of polymerization. Slight conformational change of these polymers would lead to slight variation of the distance between donor and acceptor chromophores so that the nonadiabatic interactions in the excited state between donor-acceptor pairs in these oligomers and polymers would be perturbed by such change of conformations.

  DOI：

  10.1021/ma302381y
• 作为产物：
  描述：

  苯胺 在 N-溴代丁二酰亚胺(NBS) 、 sodium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 18.0h， 生成 1,4-bis-(4-bromo-phenyl)-piperazine
  参考文献：
  名称：

  哌嗪：聚集诱导发射材料的一种有前景的构建模块

  摘要：

  我们报告哌嗪利用其供电子能力和椅式构象，成为构建聚集诱导发射（AIE）材料的有前景的构建块。哌嗪衍生物可以实现聚集过程中扭曲分子内电荷转移和非辐射衰变的抑制，从而表现出AIE特性。PA-Py +被成功设计为用于光动力治疗的新型AIE材料。

  DOI：

  10.1039/d3tc02573j

文献信息

• Schouten, Recueil des Travaux Chimiques des Pays-Bas, 1937, vol. 56, p. 541,554, 863, 871
  作者：Schouten

  DOI：——

  日期：——
• Schouten, Recueil des Travaux Chimiques des Pays-Bas, 1937, vol. 56, p. 863,870
  作者：Schouten

  DOI：——

  日期：——
• Schouten, Recueil des Travaux Chimiques des Pays-Bas, 1937, vol. 56, p. 557,872
  作者：Schouten

  DOI：——

  日期：——