N-(2-anilino-1,4-naphthoquinone-3-sulphonyl)-N'-(3'-phenyl-4'-thiazolidinon-2'-ylidene)-hydrazine | 845730-33-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N-(2-anilino-1,4-naphthoquinone-3-sulphonyl)-N'-(3'-phenyl-4'-thiazolidinon-2'-ylidene)-hydrazine
• CAS: 845730-33-8
• 化学式: C₂₅H₁₈N₄O₅S₂
• 分子量: 518.574
• InChiKey: WKINHRPPAPDIET-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.36
• 重原子数：
  36.0
• 可旋转键数：
  6.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  125.01
• 氢给体数：
  2.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  邻甲氧基苯甲醛 、 N-(2-anilino-1,4-naphthoquinone-3-sulphonyl)-N'-(3'-phenyl-4'-thiazolidinon-2'-ylidene)-hydrazine 在 三乙胺 作用下， 以 甲醇 为溶剂， 反应 10.0h， 以81%的产率得到N-(2-anilino-1,4-naphthoquinone-3-sulphonyl)-N'-[3'-phenyl-5'-(2-methoxybenzylidene)-4'-thiazolidinon-2'-ylidene]-hydrazine
  参考文献：
  名称：

  CHLOROSULPHONATION OF 2-ANILINO-1,4-NAPHTHOQUINONE AND SYNTHESIS OF NEWER SULPHONYL DERIVATIVES

  摘要：

  Synthesis of 2-anilino-1,4-napthoquinone-3-sulphonyl chloride (2) was achieved from the reaction of the title compound with chlorosulphonic acid. The interesting derivative 2 was used as a building block for synthesis of the sulphonyl derivatives 3-24. All these sulphonyl derivatives were characterized by the physical and spectral data (IR, Mass, H-1- and C-13 NMR spectra).

  DOI：

  10.1080/10426500490466869
• 作为产物：
  描述：

  2-anilino-1,4-naphthoquinone-3-sulphonyl chloride 在 吡啶 、 sodium acetate 、 一水合肼 作用下， 以 乙醇 为溶剂， 反应 13.0h， 生成 N-(2-anilino-1,4-naphthoquinone-3-sulphonyl)-N'-(3'-phenyl-4'-thiazolidinon-2'-ylidene)-hydrazine
  参考文献：
  名称：

  CHLOROSULPHONATION OF 2-ANILINO-1,4-NAPHTHOQUINONE AND SYNTHESIS OF NEWER SULPHONYL DERIVATIVES

  摘要：

  Synthesis of 2-anilino-1,4-napthoquinone-3-sulphonyl chloride (2) was achieved from the reaction of the title compound with chlorosulphonic acid. The interesting derivative 2 was used as a building block for synthesis of the sulphonyl derivatives 3-24. All these sulphonyl derivatives were characterized by the physical and spectral data (IR, Mass, H-1- and C-13 NMR spectra).

  DOI：

  10.1080/10426500490466869