2,2-dimethyl-1,2-dihydronaphthalen-1-ol | 16020-36-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2,2-dimethyl-1,2-dihydronaphthalen-1-ol
• 英文别名: 2,2-Dimethyl-1,2-dihydro-1-naphthol；Dihydrodimethylnaphthol；2,2-dimethyl-1H-naphthalen-1-ol
• CAS: 16020-36-3
• 化学式: C₁₂H₁₄O
• 分子量: 174.243
• InChiKey: UPHGWWJFHMNOGV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-oxo-2,2-dimethyl-1,2-dihydronaphthalene 在 sodium tetrahydroborate 作用下， 生成 2,2-dimethyl-1,2-dihydronaphthalen-1-ol
  参考文献：
  名称：

  Alumina-catalyzed reactions of hydroxyarenes and hydroaromatic ketones. II. Reactions of 1-oxo-2,2-dimethyl-1,2-dihydronaphthalene, 1-oxo-4,4-dimethyl-1,4-dihydronaphthalene, and 1-methoxynaphthalene with methanol

  摘要：

  DOI：

  10.1021/jo01268a037

文献信息

• Novel nucleophilic rearrangement of 1-substituted isoquinolines using an alcoholic sodium hydroxide solution
  作者：V. I. Terenin、A. A. Volkov、A. S. Ivanov、E. V. Kabanova

  DOI：10.1007/s10593-011-0722-3

  日期：2011.4

  The reactions of 1-substituted isoquinolinium salts have been studied in the cases of the 1-isopropyl-2-methyl- and 2-methyl-1-cyclohexylisoquinolinium iodides using an alcoholic solution of sodium hydroxide. The possibility of preparing a wide range of spirocyclic ketones, alcohols, amino alcohols, and isochroman-3-ones has been demonstrated.

  在碘化1-异丙基-2-甲基和2-甲基-1-环己基异喹啉鎓的情况下，使用氢氧化钠的醇溶液研究了1-取代异喹啉鎓盐的反应。已经证明制备多种螺环酮，醇，氨基醇和异色满-3-酮的可能性。
• Influence of Electron-Donor Sensitizers on SET-Promoted Photochemical Reactions of β,γ-Unsaturated Aldehydes
  作者：Diego Armesto、Maria J. Ortiz、Antonia R. Agarrabeitia、Mar Martin-Fontecha

  DOI：10.1021/ol049263e

  日期：2004.6.1

  beta,gamma-Unsaturated aldehydes undergo photochemical oxa-di-pi-methane and decarbonylation reactions using DMN as an electron-donor sensitizer, whereas, using DMA, other photoproducts resulting from proton abstraction by ketyl- and alkene-centered radical-anions are also obtained.

  使用DMN作为电子给体敏化剂时，β，γ-不饱和醛会经历光化学的oxa-di-pi-甲烷和脱羰反应，而使用DMA时，酮基和烯烃中心的自由基阴离子质子提取所产生的其他光产物也是获得。
• Alumina-catalyzed reactions of hydroxyarenes and hydroaromatic ketones. II. Reactions of 1-oxo-2,2-dimethyl-1,2-dihydronaphthalene, 1-oxo-4,4-dimethyl-1,4-dihydronaphthalene, and 1-methoxynaphthalene with methanol
  作者：Joseph Shabtai、LeRoy H. Klemm、Dennis Riley Taylor

  DOI：10.1021/jo01268a037

  日期：1968.4