4-hydroxy-1-(1-heptyloxy)-2,2,6,6-tetramethylpiperidine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 4-hydroxy-1-(1-heptyloxy)-2,2,6,6-tetramethylpiperidine
• 英文别名: 1-Heptoxy-2,2,6,6-tetramethylpiperidin-4-ol
• 化学式: C₁₆H₃₃NO₂
• 分子量: 271.444
• InChiKey: ACDWMGHXZXEWPZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  32.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-hydroxy-1-(1-heptyloxy)-2,2,6,6-tetramethylpiperidine 、 甲基丙烯酸酐 在 吡啶 、 4-二甲氨基吡啶 作用下， 反应 22.0h， 以22%的产率得到4-methacryloyloxy-1-(1-heptoxy)-2,2,6,6-tetramethylpiperidine
  参考文献：
  名称：

  Strategies for the Generation of Molecularly Imprinted Polymeric Nitroxide Catalysts

  摘要：

  [GRAPHICS]Two strategies for preparing catalytically active molecularly imprinted nitroxide-containing polymers are outlined. Both strategies rely upon the thermal rearrangement chemistry of tertiary amine N-oxides. To this end, several polymers were prepared and the polymeric nitroxides were revealed by oxidation with m-CPBA. All of the resulting polymeric catalysts proved to be competent mediators of the oxidation of alcohols.

  DOI：

  10.1021/ol051749n
• 作为产物：
  描述：

  阻聚剂701 、 1-碘庚烷 在 三正丁基氢锡 作用下， 以 苯 为溶剂， 反应 5.0h， 以48%的产率得到4-hydroxy-1-(1-heptyloxy)-2,2,6,6-tetramethylpiperidine
  参考文献：
  名称：

  Strategies for the Generation of Molecularly Imprinted Polymeric Nitroxide Catalysts

  摘要：

  [GRAPHICS]Two strategies for preparing catalytically active molecularly imprinted nitroxide-containing polymers are outlined. Both strategies rely upon the thermal rearrangement chemistry of tertiary amine N-oxides. To this end, several polymers were prepared and the polymeric nitroxides were revealed by oxidation with m-CPBA. All of the resulting polymeric catalysts proved to be competent mediators of the oxidation of alcohols.

  DOI：

  10.1021/ol051749n

文献信息

• PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS
  申请人：BASF SE

  公开号：EP2035381B1

  公开（公告）日：2010-12-29
• US5204473A
  申请人：——

  公开号：US5204473A

  公开（公告）日：1993-04-20
• Strategies for the Generation of Molecularly Imprinted Polymeric Nitroxide Catalysts
  作者：Christopher D. Anderson、Kenneth J. Shea、Scott D. Rychnovsky

  DOI：10.1021/ol051749n

  日期：2005.10.1

  [GRAPHICS]Two strategies for preparing catalytically active molecularly imprinted nitroxide-containing polymers are outlined. Both strategies rely upon the thermal rearrangement chemistry of tertiary amine N-oxides. To this end, several polymers were prepared and the polymeric nitroxides were revealed by oxidation with m-CPBA. All of the resulting polymeric catalysts proved to be competent mediators of the oxidation of alcohols.