Tris(2-aminoethyl)azanium | 439293-14-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Tris(2-aminoethyl)azanium
• 英文别名: tris(2-aminoethyl)azanium
• CAS: 439293-14-8
• 化学式: C₆H₂₁N₄
• 分子量: 149.26
• InChiKey: MBYLVOKEDDQJDY-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  10
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  82.9
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  镉 、 Tris(2-aminoethyl)azanium 生成 cadmium(trn) ion
  参考文献：
  名称：

  Stability of Chelate Complexes

  摘要：

  最近人们的注意力集中在二价金属离子与不同配体形成的络合物的稳定常数顺序上的平行性1,2。我们研究了金属离子与β,β',β"-三氨基三乙胺, N(CH2CH2NH2)3, (tren) 形成的络合物的稳定常数，它可以为给定离子提供四个配体原子，如 Mann 先前所示Pope3 制备了这种四胺与几种二价离子的络合物。通过将酸 (trenH3)3+ 的酸度常数与反应的平衡常数相结合来评估稳定性常数：

  DOI：

  10.1038/163723b0
• 作为产物：
  描述：

  [Co(tris(2-aminoethyl)amine)(H2O)2](2+) 以 高氯酸 为溶剂， 生成 钴 、 Tris(2-aminoethyl)azanium
  参考文献：
  名称：

  Kinetics of the acid dissociation of cyclic and open-chain tetramine complexes of cobalt(II): general acid catalysis with co-ordinating phosphate—citric acid buffers

  摘要：

  The kinetics of dissociation of the cobalt(II) complexes of the quadridentate ligands 1,4,8,11-tetra-azacyclotetradecane (cyclam). triethylenetetramine (trien) and 2,2',2'-triaminotriethylamine (tren) was followed spectrophotometrically in the ranges 10 < T < 50-degrees-C and 0.8 < pH < 4.0 in perchloric acid and McIlvaine phosphate-citrate buffer system, an an ionic strength / = 1.0 mol dm-3, NaClO4. The complexes were prepared in situ in preaerated solutions under a nitrogen atmosphere, by the addition of a 10% excess of the ligand in the form of the free base to a solution of CoCl2.6H2O. The ligand dissociation reaction was then initiated by the addition of perchloric acid or McIlvaine phosphate-citrate buffer. No dissociation was observed for the cyclam complex in perchloric acid media. It was, however, observed in the buffer and obeyed biphasic kinetics comprising two consecutive first-order steps. The action of the phosphate and/or citrate is attributed to their complexing ability and to their association through hydrogen bonding to the axial aqua ligand. thus bringing the proton closer to the dissociating nitrogen and hence catalysing the dissociation. The dissociation kinetics of the open-chain unbranched trien and the tripod tren was observed in perchloric acid as well as the McIlvaine buffer system. Except when too fast to follow by conventional spectrophotometry, the reaction obeyed biphasic kinetics comprising two consecutive first-order steps. The tren complex dissociates at a rate 5-10 times faster than that of trien, the first step being too fast to follow except at 10-degrees-C in the buffer system. The observed rate dependence is explained on the basis of mechanisms involving solvation, specific acid catalysis and general acid catalysis. The cyclam complex dissociates at a rate 5-30 times slower than those of the two open-chain complexes. This is attributed to the stabilization due to the hindered rotation of the dissociating nitrogen (entropic effect) and to the higher ligand-field stabilization of the macrocycle (enthalpic effect). Mechanisms covering the entire range of pH studied and conforming to the observed rate laws are given.

  DOI：

  10.1039/dt9930002313

文献信息

• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Cd: SVol., 17.3, page 753 - 754
  作者：

  DOI：——

  日期：——
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Ag: MVol.B6, 1.4.5, page 65 - 66
  作者：

  DOI：——

  日期：——
• Prue, J. E.; Schwarzenbach, G., Helvetica Chimica Acta, 1950, vol. 33, p. 963 - 974
  作者：Prue, J. E.、Schwarzenbach, G.

  DOI：——

  日期：——
• Schwarzenbach, G., Helvetica Chimica Acta, 1953, vol. 36, p. 23 - 36
  作者：Schwarzenbach, G.

  DOI：——

  日期：——
• Zinc(II) and cobalt(II) induced amide deprotonation in bis(N-2-acetamido)iminodiacetato) chelates
  作者：Edward A. Lance、Robert Nakon

  DOI：10.1016/s0020-1693(00)90752-7

  日期：1981.1