2-chloro-cyclohexylamine | 55005-83-9

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代烷
• 英文名称: 2-chloro-cyclohexylamine
• 英文别名: 2-Chlor-1-amino-cyclohexan；2-Chlor-cyclohexylamin；1-Amino-2-chlor-cyclohexan；2-Chlorocyclohexan-1-amine
• CAS: 55005-83-9
• 化学式: C₆H₁₂ClN
• 分子量: 133.621
• InChiKey: RTZWBJIYBWNJMR-UHFFFAOYSA-N

物化性质

• 沸点：
  85 °C(Press: 15 Torr)
• 密度：
  1.082 g/cm3(Temp: 25 °C)

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  光气 、 2-chloro-cyclohexylamine 生成 6-Chlorocyclohexyl isocyanate
  参考文献：
  名称：

  Ivanov, M. G.; Zhuravlev, E. Z.; Dergunov, Yu. I., Journal of general chemistry of the USSR, 1990, vol. 60, # 6, p. 1078 - 1081

  摘要：

  DOI：
• 作为产物：
  描述：

  2-Chlor-1-azido-cyclohexan 在 platinum(IV) oxide 氢气 作用下， 以 甲醇 为溶剂， 生成 2-chloro-cyclohexylamine
  参考文献：
  名称：

  Minisci,F. et al., Gazzetta Chimica Italiana, 1964, vol. 94, p. 67 - 90

  摘要：

  DOI：

文献信息

• PROCESS FOR PREPARING AMINE COMPOUND
  申请人：Watanabe Masahito

  公开号：US20120065426A1

  公开（公告）日：2012-03-15

  The present invention aims to provide a practical process for preparing amine compounds through a generalized highly-diastereoselective reductive amination reaction. The present invention relates to a process for diastereoselectively preparing an amine compound using a catalyst employed in a reductive amination reaction, comprising a specific organometallic compound represented by the following general formula (1):

  本发明旨在通过一种广义高对映选择性还原胺化反应的实用过程来制备胺化合物。本发明涉及一种在还原胺化反应中使用的催化剂来对映选择性地制备胺化合物的过程，包括由以下一般式（1）表示的特定有机金属化合物。
• CATALYSTS AND METHODS FOR POLYMER SYNTHESIS
  申请人：NOVOMER, INC.

  公开号：US20130144032A1

  公开（公告）日：2013-06-06

  The present invention provides unimolecular metal complexes having increased activity in the copolymerization of carbon dioxide and epoxides. Also provided are methods of using such metal complexes in the synthesis of polymers. According to one aspect, the present invention provides metal complexes comprising an activating species with co-catalytic activity tethered to a multidentate ligand that is coordinated to the active metal center of the complex.

  本发明提供了在二氧化碳和环氧化物的共聚合中具有增强活性的单分子金属配合物。还提供了使用这种金属配合物在合成聚合物中的方法。根据一个方面，本发明提供了包括与具有共催化活性的活化物种相耦合的多齿配体的金属配合物，该多齿配体与复合物的活性金属中心配位。
• Benzenesulfonyl ureas
  申请人：Hoechst Aktiengesellschaft

  公开号：US03932503A1

  公开（公告）日：1976-01-13

  Benzenesulfonyl-ureas having hypoglycemic activity and corresponding to the formula ##SPC1## Wherein R.sup.1 is A. cyclopentyl, lower alkyl-cyclopentyl, dimethyl-cyclopentyl, tri-methyl-cyclopentyl, tetramethyl-cyclopentyl, chloro-cyclopentyl; B. di-lower-alkyl-cyclohexyl, lower alkoxymethyl-cyclohexyl; chloro-cyclohexyl; C. cycloalkenyl with 5-8 ring carbon atoms; methyl-cyclopentenyl, methyl-cyclohexenyl; di-methyl-cyclohexenyl, tri-methyl-cyclopentenyl; ##SPC2## In which A stands for hydrogen, halogen, lower alkyl, lower alkoxy, lower alkenoxy, methoxy-loweralkoxy, lower acyl, nitrophenyl or trifluoromethyl, A.sup.1 stands for hydrogen, lower alkoxy, lower alkyl or halogen and B stands for hydrogen, lower alkyl, lower alkoxy, halogen, benzyloxy or methoxy-methoxy; Y is a hydrocarbon chain of 1-3 carbon atoms, or a physiologically tolerable salt thereof.

  苯磺酰脲具有降血糖活性，其对应于以下式子：##SPC1## 其中，R.sup.1为A. 环戊基，较低烷基-环戊基，二甲基-环戊基，三甲基-环戊基，四甲基-环戊基，氯-环戊基；B. 二较低烷基-环己基，较低烷氧甲基-环己基；氯-环己基；C. 碳原子数为5-8的环烷基；甲基-环戊烯基，甲基-环己烯基；二甲基-环己烯基，三甲基-环戊烯基；##SPC2## 其中，A代表氢，卤素，较低烷基，较低烷氧基，较低烯氧基，甲氧基-较低烷氧基，较低酰基，硝基苯基或三氟甲基，A.sup.1代表氢，较低烷氧基，较低烷基或卤素，B代表氢，较低烷基，较低烷氧基，卤素，苄氧基或甲氧基-甲氧基；Y为1-3个碳原子的碳氢链，或其生理耐受盐。
• AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE
  申请人：Kobayashi Yumi

  公开号：US20110201687A1

  公开（公告）日：2011-08-18

  An amide derivative represented by the following Formula (1) is provided as an amide derivative showing a significantly excellent effect for a pest control action. In the following Formula (1), A represents a carbon atom, a nitrogen atom, or the like, and K represents a non-metal atomic group necessary for forming a cyclic linking group derived from benzene or a heterocyclie. X represents a halogen atom or the like; n represents an integer of from 0 to 4 . R 1 and R 2 represent hydrogen atoms, alkyl groups, or the like. T represents —C(=G 1 )-Q 1 or —C(=G 1 )-G 2 Q 2 , and G 1 to G 3 each represent oxygen atoms or the like. Q 1 and Q 2 each represent a hydrogen atom, an alkyl group, an aryl group, or the like. Y 1 and Y 5 each represent a halogen atom or the like, Y 2 and Y 4 each represent a hydrogen atom or the like, and Y 3 represents a C2-C5 haloalkyl group.

  提供以下式子（1）表示的酰胺衍生物，作为一种表现出显著杀虫作用的酰胺衍生物。在下面的式子（1）中，A代表碳原子、氮原子或类似物，K代表必要的非金属原子团，用于形成从苯或杂环中得到的环链连接基。X代表卤素原子或类似物；n代表0至4的整数。R1和R2代表氢原子、烷基或类似物。T代表- C（= G1）- Q1或- C（= G1）- G2Q2，G1到G3每个代表氧原子或类似物。Q1和Q2每个代表氢原子、烷基、芳基或类似物。Y1和Y5每个代表卤素原子或类似物，Y2和Y4每个代表氢原子或类似物，Y3代表C2-C5卤代烷基。
• POLYMERIZATION CATALYST COMPOSITION AND PROCESS FOR PRODUCTION OF POLYMER
  申请人：Mitsui Chemicals, Inc.

  公开号：EP1857471A1

  公开（公告）日：2007-11-21

  A polymerization catalyst composition for a radically polymerizable monomer of the present invention comprises a transition metal-containing phosphazenium composition which is produced by mixing a phosphazenium compound with a compound of a transition metal belonging to Groups 4 to 12 in the periodic table and an organic halogen compound.

  用于本发明可辐射聚合单体的聚合催化剂组合物包括一种含过渡金属的磷铵组合物，该组合物是通过将磷铵化合物与一种属于元素周期表中第 4 至 12 族的过渡金属化合物和一种有机卤素化合物混合而制得的。