1,2-bis-(2,3t-diphenyl-acryloyloxy)-ethane | 103398-50-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 1,2-bis-(2,3t-diphenyl-acryloyloxy)-ethane
• 英文别名: 1,2-bis-(2,3t-diphenyl-acryloyloxy)-ethane；1,2-Bis-(2,3t-diphenyl-acryloyloxy)-aethan
• CAS: 103398-50-1
• 化学式: C₃₂H₂₆O₄
• 分子量: 474.556
• InChiKey: WPLSONPEAGAKMZ-HCTXVGCHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.55
• 重原子数：
  36.0
• 可旋转键数：
  9.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  52.6
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  苯可丁酸乙酸酯 在 吡啶 、 氯化亚砜 、 苯 作用下， 生成 1,2-bis-(2,3t-diphenyl-acryloyloxy)-ethane
  参考文献：
  名称：

  Carbon isotope fluctuations through the neoproterozoic-lower Cambrian Birmania basin, Rajasthan, India

  摘要：

  The results of a carbon isotope study from a hitherto unexplored marine sediments from the Birmania basin, Northwestern India are reported, which documents significant isotope variation across the Precambrian-Cambrian boundary (Pc/C). An attempt has been made to identify carbon isotope chronostratigraphic marker for the Precambrian-Cambrian boundary in the sedimentay succession. The transition is marked by a negative excursion during phosphoritic activity at the base of the Birmania succession which is followed by a positive excursion close to the boundary and a swing back to less positive values in the Early Cambrian. The characteristics of the paleoenvironment during the transition interval is also discussed.

  DOI：

  10.1007/bf03175656

文献信息

• Phosphine-Catalyzed Stereoselective Ring-Opening Addition of Cyclopropenones with Nucleophiles
  作者：LuLu Yang、Xin He、Jiao Jiao、Yuhai Tang、Jing Li、Yang Li、Ruixia Gao、Yong Wu、Silong Xu

  DOI：10.1021/acs.joc.3c00603

  日期：2023.7.7

  A phosphine-catalyzed ring-opening addition reaction of cyclopropenones with a variety of nucleophiles (NuH), including oxygen-, nitrogen-, sulfur-, and carbon-based ones, has been investigated, which produces potentially useful α,β-unsaturated carbonyl derivatives in high yields (up to 99%), high regioselectivity, and exclusive E-selectivity. The reaction proceeds in high efficiency under very mild

  已经研究了环丙烯酮与各种亲核试剂 (NuH)（包括氧基、氮基、硫基和碳基试剂）的膦催化开环加成反应，该反应产生潜在有用的 α,β-不饱和羰基衍生物具有高产率（高达 99%）、高区​​域选择性和独特的E选择性。该反应在非常温和的条件下仅使用 1 mol% PPh 3即可高效进行在室温下作为催化剂。当使用氘代亲核试剂 (NuD) 时，该方法还适用于合成氘代烯烃。通过实验和DFT计算对该机制进行了研究，表明α-烯酮基磷叶立德是催化循环中的关键中间体，能够以立体选择性方式捕获亲核试剂。