<4-(Dimethylamino)phenyl>phosphan | 53772-56-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: <4-(Dimethylamino)phenyl>phosphan
• 英文别名: N,N-dimethyl-4-phosphanyl-aniline；4-Dimethylaminophenylphosphin；4-(Dimethylamino)phenylphosphine；N,N-dimethyl-4-phosphanylaniline
• CAS: 53772-56-8
• 化学式: C₈H₁₂NP
• 分子量: 153.164
• InChiKey: FMYPJTRYAPFMCM-UHFFFAOYSA-N

物化性质

• 沸点：
  243.3±23.0 °C(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  tert-butyldiethinylphosphane 、 <4-(Dimethylamino)phenyl>phosphan 在 氢氧化钾 、 18-冠醚-6 作用下， 以 苯 为溶剂， 生成 4-(4-tert-butyl-4H-[1,4]diphosphinin-1-yl)-N,N-dimethyl-aniline
  参考文献：
  名称：

  Maerkl,G. et al., Synthesis, 1977, p. 842 - 845

  摘要：

  DOI：

文献信息

• [EN] 3-SUBSTITUTED 2-AMINO-INDOLE DERIVATIVES<br/>[FR] DÉRIVÉS DE 2-AMINO-INDOLE 3-SUBSTITUÉS
  申请人：TAKEDA PHARMACEUTICAL

  公开号：WO2015198045A1

  公开（公告）日：2015-12-30

  The present invention provides compounds of formula (I) (Formula (I)) and pharmaceutically acceptable salts thereof, wherein Q, X% X4,X5 X6, X7,R1, R2, R3 and R8 are as defined in the specification, processes for the preparation of such compounds, pharmaceutical compositions containing them and the use of such compounds in therapy.

  本发明提供了公式(I)（公式(I)）的化合物及其药用可接受的盐，其中Q，X，X4，X5，X6，X7，R1，R2，R3和R8如说明书中所定义，这些化合物的制备方法，包含它们的药物组合物以及这些化合物在治疗中的用途。
• Metal Complex Compound, Hydrogen Production Catalyst and Hydrogenation Reaction Catalyst Each Comprising the Metal Complex Compound, and Hydrogen Production Method and Hydrogenation Method Each Using the Catalyst
  申请人：Muranaka Makoto

  公开号：US20130244865A1

  公开（公告）日：2013-09-19

  Provided is a catalyst for producing hydrogen, which catalyst has higher performance than conventional catalysts since, for example, it exhibits a certain high level of activity in an aqueous formic acid solution at high concentration even without addition of a solvent, amine and/or the like. The metal phosphine complex is a metal phosphine complex represented by General Formula (1): MH m (CO)L n , wherein M represents an iridium, iron, rhodium or ruthenium atom; in cases where M is an iridium or rhodium atom, m=3 and n=2, and in cases where M is an iron or ruthenium atom, m=2 and n=3; and the number n of Ls each independently represent a tri-substituted phosphine represented by General Formula (2): PR 1 R 2 R 3 . The catalyst for producing hydrogen comprises the metal phosphine complex as a constituent component.

  提供的是一种用于产生氢气的催化剂，该催化剂具有比传统催化剂更高性能的特点，例如，在高浓度的水甲酸溶液中即使没有溶剂、胺或类似物的添加，也表现出一定水平的活性。金属膦配合物是由通用公式（1）表示的金属膦配合物：MHm(CO)Ln，其中M代表铱、铁、铑或钌原子；在M为铱或铑原子的情况下，m=3且n=2，在M为铁或钌原子的情况下，m=2且n=3；L的数量n分别代表由通用公式（2）表示的三取代膦：PR1R2R3。用于产生氢气的催化剂包括金属膦配合物作为组成部分。
• [EN] METHODS AND INTERMEDIATES FOR PREPARING A THERAPEUTIC COMPOUND USEFUL IN THE TREATMENT OF RETROVIRIDAE VIRAL INFECTION<br/>[FR] PROCÉDÉS ET INTERMÉDIAIRES POUR PRÉPARER UN COMPOSÉ THÉRAPEUTIQUE UTILE DANS LE TRAITEMENT D'UNE INFECTION VIRALE PAR RETROVIRIDAE
  申请人：GILEAD SCIENCES INC

  公开号：WO2019161280A1

  公开（公告）日：2019-08-22

  The present disclosure relates to methods and intermediates useful for preparing a compound of formula (I): (I) or a co-crystal, solvate, salt or combination thereof.

  本公开涉及用于制备化合物(I)的方法和中间体，该化合物的结构如下：(I)，或其共晶体、溶剂合物、盐或其组合物。
• RECOVERY AND/OR REUSE OF PALLADIUM CATALYST AFTER A SUZUKI COUPLING
  申请人：Dow AgroSciences LLC

  公开号：US20160340311A1

  公开（公告）日：2016-11-24

  Methods for the recovery and/or reuse of palladium catalyst after a Suzuki coupling reaction in which two molecules are coupled are described.

  本文介绍了在Suzuki偶联反应中，两种分子被耦合后回收和/或再利用钯催化剂的方法。
• Bathochromic mono-and bis-acylphosphine oxides and sulfides and their use as photoinitiators
  申请人：——

  公开号：US20040204613A1

  公开（公告）日：2004-10-14

  Compounds of formula (I), wherein A is S or O; x is 0 or 1; a is SR 10 or N(R 11 )(R 12 ); R 1 and R 2 are C 1 -C 24 alkyl, OR 10 , CF 3 or halogen; R 3 , R 4 and R 5 are hydrogen, C 1 -C 24 alkyl, OR 10 or halogen; or two of the radicals R 11 R 21 R 31 R 4 and/or R 9 together form C 1 -C 2 oalkylene uninterrupted or interrupted by O, S or NR 13 ; R 6 , R 11 R 8 and R 9 are hydrogen, C 1 -C 24 alkyl; C 2 -C 24 alkyl which is interrupted one or more times by non-consecutive O atoms and unsubstituted or substituted by OH and/or SH, or R 6 , R 7 , R 8 and Rg are OR 10 ; halogen; or phenyl unsubstituted or substituted one or more times by C-Calkyl; R 10 , R 11 and R 12 are e.g. hydrogen; X is e.g. (II), and R 2 ; have one of the meanings given for R 1 and R 2 ; and R 3 ′, R 4 ′ and Rs′ have one of the meanings given for R 3 , R 4 and R 5 ; are suitable as photoinitiators, especially for irradiation with light of relatively long wavelengths. 1

  式(I)的化合物，其中A为S或O；x为0或1；a为SR10或N（R11）（R12）；R1和R2为C1-C24烷基，OR10，CF3或卤素；R3，R4和R5为氢，C1-C24烷基，OR10或卤素；或者R11R21R31R4和/或R9中的两个基团通过O，S或NR13中断或不中断地形成C1-C2烷基；R6，R11R8和R9为氢，C1-C24烷基；由非连续的O原子中断一次或多次并由OH和/或SH未取代或取代的C2-C24烷基，或者R6，R7，R8和Rg为OR10；卤素；或苯基未取代或取代一次或多次的C-C烷基；R10，R11和R12例如为氢；X例如为（II），并且R2具有R1和R2给出的含义之一；R3'，R4'和Rs'具有R3，R4和R5给出的含义之一；适用于光引发剂，特别是对于相对较长波长的光辐射。